Self-ligating brackets exhibit accumulation of high levels of periodontopathogens in gingival crevicular fluid

Bergamo, Ana Zilda Nazar; Casarin, Renato Corrêa Viana; Nascimento, Cássio do; Matsumoto, Mírian Aiko Nakane; Carvalho, Fabrício Kitazono de; Silva, Léa Assed Bezerra da; Nelson‐Filho, Paulo

doi:10.1007/s10266-021-00677-2

Cited by 4 publications

(2 citation statements)

References 27 publications

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“…37 While P. gingivalis was not specifically identified, F. nucleatum and P. intermedia, two members of the orange complex (along with Parvimonas micra, Campylobacter rectus, and Eubacterium nodatum), were studied. 38 The results indicated a significant presence of F. nucleatum in CLA as previously reported, 39 and also a higher load in SLA. The findings agreed with those of Bergamo et al in which the species related to the red and orange complexes, including F. nucleatum, showed the highest in situ levels on selfligating appliances 30 and 60 days after placement.…”

Section: Discussionsupporting

confidence: 64%

Dysbiotic changes of periodontal pathogens in patients wearing conventional and self-ligating orthodontic appliances

Cota-Quintero

Bermúdez

Ramos‐Payán

et al. 2023

Australasian Orthodontic Journal

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Objective: This study aimed to analyse dysbiotic changes of periodontal pathogenic bacteria and their relationship with different types of fixed orthodontic appliances in a population located in Northwestern Mexico. Methods: Three groups of patients were identified: a control group without orthodontic appliances (C), a conventional-ligating appliance group (CLA), and a self-ligating appliance group (SLA). Periodontal biofilm samples were collected for DNA extraction to identify the presence and load of Treponema denticola, Prevotella intermedia, and Fusobacterium nucleatum, using a quantitative real-time PCR technique. Results: A total of 92 patients were included. The results showed that F. nucleatum was present in all groups including the control patients (C 96%, CLA 100%, and SLA 67%, respectively). Female participants displayed a higher frequency of periodontal pathogens than males, but males were more affected by F. nucleatum. In addition, the presence of T. denticola and P. intermedia was time-dependent, being more frequent in patients in treatment for longer than 12 months whereas CLA showed 74% and 78% of positive samples and SLA showed 78% and 89%, respectively. F. nucleatum was present in 100% of CLA samples before and after 12 months of treatment and its load was higher in the SLA group after 12 months. Conclusions: Dysbiotic changes that could affect the periodontal tissues were seen in patients wearing orthodontic appliances. The frequency of F. nucleatum was significantly higher in CLA and noted with a greater load in SLA. In addition, female participants showed a higher frequency of periodontal pathogens while male subjects were more affected by F. nucleatum. As expected, treatment for longer than 12 months correlated with a higher frequency of all periodontal pathogens. The results support the concept that dysbiosis leading to periodontal disease can be caused by the rise of a dominant species, instead of the appearance of a new species.

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Section: Discussionsupporting

confidence: 64%

Dysbiotic changes of periodontal pathogens in patients wearing conventional and self-ligating orthodontic appliances

Cota-Quintero

Bermúdez

Ramos‐Payán

et al. 2023

Australasian Orthodontic Journal

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“…The use of fixed orthodontic appliances affects the composition of the subgingival microbiota from the early stages of treatment, which increases the prevalence of Pg and other periodontal pathogens [14] . The increase in Pg levels depends on the appliance used, as some types of brackets provide more retentive sites than others [15,16] . More contamination of this bacterium has been observed in metal brackets than in clear aligners.…”

Section: Orthodonticmentioning

confidence: 99%

Porphyromonas gingivalis, an Orthodontic point of view

Sanchez¹,

Moyeda²,

Ibarra³

et al. 2022

Int. J. Appl. Dent. Sci.

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Introduction: Porphyromonas gingivalis (Pg) levels progressively increase in quantity and quality in the course of orthodontic treatment posing a risk to periodontal health. Objective:To analyze the existing literature on the prevalence, clinical manifestations, diagnostic methods, treatment and prevention of Porphyromonas gingivalis from a systemic, oral and orthodontic point of view. Methodology: A literature review was carried out by searching databases using the keywords: "Porphyromonas gingivalis", "prevalence", "orthodontics", "treatment", "prevention", "diagnosis", "levels", "systemic", "treatment" and "periodontitis". Results: There is a 68.2% prevalence of Pg in periodontal pockets which increases during orthodontic treatment. Its main clinical manifestations in orthodontic treatment are increased depth and bleeding on probing, decreased level of clinical attachment and increased gingival and periodontal index. Pg is detected by measuring salivary MMP-9 levels by ELISA and intraoral clinical examination. Treatment for Pg infection includes mechanical therapy and adjuvant therapies such as the use of amoxicillin and metronidazole, chitosan and azithromycin or azithromycin alone. Toothbrushing and interproximal cleaning are the cornerstones of preventing the occurrence of Pg during orthodontic treatment, in conjunction with oral and periodontal hygiene education. Conclusion: Pg levels increase during orthodontic treatment, which implies a risk for the development of periodontitis during and after treatment, its prevention is important at all stages of treatment.

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Dynamics of the oral microbiome during orthodontic treatment and antimicrobial advances for orthodontic appliances

Niu,

Chen,

Bai

et al. 2024

iScience

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Self-ligating brackets exhibit accumulation of high levels of periodontopathogens in gingival crevicular fluid

Cited by 4 publications

References 27 publications

Dysbiotic changes of periodontal pathogens in patients wearing conventional and self-ligating orthodontic appliances

Dysbiotic changes of periodontal pathogens in patients wearing conventional and self-ligating orthodontic appliances

Porphyromonas gingivalis, an Orthodontic point of view

Dynamics of the oral microbiome during orthodontic treatment and antimicrobial advances for orthodontic appliances

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