Self-monitoring of blood glucose in diabetic pregnancy.

Peacock, Ian; Hunter, J. C.; Walford, S; Allison, S.P.; Davison, J.Kenneth; Clarke, Pat; Symonds, E. M.; Tattersall, R. B.

doi:10.1136/bmj.2.6201.1333

Cited by 57 publications

(16 citation statements)

References 11 publications

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“…In the past the successful outcome of these pregnancies was universally accepted to be poor [11,17], and pregnancy was contraindicated in such patients mainly due to accelerated deterioration of renal function, high perinatal mortality rates, as well as a higher incidence of congenital malformations, and poor prognosis for the newborn [23]. In view of recent stress on maternal normoglycemia all during pregnancy and in the preconceptional period, improved outcome of diabetic pregnancies has been secured [8,10,18,22]. Nevertheless, when the woman in whom diabetes is complicated by diabetic nephropathy desires children, the situation must be seriously evaluated.…”

Section: Introductionmentioning

confidence: 99%

Pregnancy complicated by diabetic nephropathy

Dicker¹,

Feldberg²,

Peleg³

et al. 1986

Journal of Perinatal Medicine

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Diabetes mellitus is a high risk complication of pregnancy and this is particularly true whenever long standing diabetes is complicated by diabetic nephropathy. Five cases are reported of diabetic pregnancy complicated by nephropathy. Four women delivered healthy babies, and one patient aborted spontaneously in the 9th week of gestation. It is suggested that first and foremost in complicated diabetic pregnancy strict normoglycemia should be adhered to prior and all through pregnancy. Our findings based on these cases also suggest that: Pregnancy does not adversely affect the renal status of a diabetic woman or vice versa. Creatinine clearance is not worsened by the course of pregnancy in the majority of these patients and proteinuria per se does not add additional risks to pregnancy or outcome. Hypertension is a separate risk factor affecting the pregnancy despite normoglycemia. Motivation of these patients to maintain normoglycemia as well as bed rest for prolonged periods, intensive use of fetal monitoring, evaluation of fetal lung maturity and improved neonatal care may contribute to improved perinatal outcome.

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Section: Introductionmentioning

confidence: 99%

Pregnancy complicated by diabetic nephropathy

Dicker¹,

Feldberg²,

Peleg³

et al. 1986

Journal of Perinatal Medicine

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“…We too have achieved a significantly better BG regulation since we adopted the self-test regime (1,5,9,14) (Table 111) and we have had the opportunity to evaluate the effect of this on a regime which otherwise continued without further change. The BG values estimated by the laboratory at the ambulant visits decreased significantly and the number of necessary hospitalizations because of diabetic-related complications during pregnancy fell to approximately 50% without having to increase the number of ambulant check-ups.…”

Section: Discussionmentioning

confidence: 99%

Diabetes Mellitus and Pregnancy: A seven‐year material of pregnant diabetics, where control during pregnancy was based on a centralized ambulant regime

Klebe

Espersen

Allen

1986

Acta Obstet Gynecol Scand

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A 7-year survey of the outcome of pregnancy complicated by diabetes mellitus, carried out at the Aarhus center, is presented. The material comprised 344 diabetic pregnant women where the control was based mainly on a centralized ambulant regime. The latter half-period was moreover based on self-monitoring of the blood glucose level. This achieved a significantly better blood glucose regulation, with a reduction of the mean blood glucose level from 7.9 to 6.4 mmol/l. Furthermore, the introduction of self-monitoring halved the number of hospitalizations necessary for blood glucose regulation. Pregnancy was complicated in about 35%. The importance of screening for urinary tract infection is emphasized, since this, which was present in 20% of cases, might be a possible factor in ketoacidosis and/or intra-uterine growth retardation. In 19% of the vaginal births it was deemed necessary to give instrumental assistance; 5% had shoulder dystocia. The cesarean section frequency was 31%. The antenatal mortality rate was 1.2% and the uncorrected perinatal mortality was 3.5%, half of the neonatal mortality was due to fatal congenital malformations. About half of the newborn babies required immediate intensive neonatal treatment. Because of the high frequency of complications in pregnant diabetics, during childbirth and in the neonatal period, centralized monitoring by a highly specialized team is necessary in order to maintain the present relatively low perinatal mortality and morbidity rates and the low number of cesarean sections, together with the most convenient control regimen for this highly pathological group. Furthermore, centralization will facilitate research which, together with prepregnancy consultation, may reduce the frequency of major fetal malformations.

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“…Thereafter, industry became actively involved in the development and commercialization of biosensor production, and the first-generation product for blood glucose testing launched into the market in 1979. 2 The second generation of biosensors was defined by the use of an antibody or receptor protein as recognition components with a more diversified selection of transducers, such as a field effect semiconductor, 3 pressure of the transistor, 4 an optical fiber, 5 or a surface acoustic wave filter. 6 In 1985, the Pharmacia company successfully developed the surface plasma resonance technique, which pushed biosensor detection limits down to as low as 10 –11 g/mL and made real-time detection of biological interactions possible.…”

Section: Biosensor Overviewmentioning

confidence: 99%

JALA Special Issue: New Developments in Biosensing Technologies

2015

SLAS Technology

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Self-monitoring of blood glucose in diabetic pregnancy.

Cited by 57 publications

References 11 publications

Pregnancy complicated by diabetic nephropathy

Pregnancy complicated by diabetic nephropathy

Diabetes Mellitus and Pregnancy: A seven‐year material of pregnant diabetics, where control during pregnancy was based on a centralized ambulant regime

JALA Special Issue: New Developments in Biosensing Technologies

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