Self-Setting Calcium Orthophosphate (CaPO4) Formulations

Dorozhkin, Sergey V.

doi:10.1007/978-981-10-5975-9_2

Cited by 6 publications

(3 citation statements)

References 733 publications

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“…The hardening of the paste is obtained in vivo by crystallization of phosphocalcic nanomaterial. Phosphocalcic cements are known today for their bioactivity which promotes bone reconstruction [ 31 , 32 ].…”

Section: Methodsmentioning

confidence: 99%

Automatic computation of bone defective volume from tomographic images

Ezzahmouly

Essakhi²,

Ouahli

et al. 2022

Heliyon

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Section: Methodsmentioning

confidence: 99%

Automatic computation of bone defective volume from tomographic images

Ezzahmouly

Essakhi²,

Ouahli

et al. 2022

Heliyon

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“…This test is done by added silver nitrate on prepared Hydroxyapatite from seashell to know this compound ortho or di or metaphosphorous by the color of precipitation that formed (Clarence, 1964) [5]. Depending on the method of preparation different crystal forms of silver phosphate can be produced of the same lattice structure the reaction can be used to know the biocompatibility of orthophosphate (Dorozhkin) [8].…”

Section: Estimation By Chemical Test (Silver Nitrate Test)mentioning

confidence: 99%

“…By stimulating the activity of osteoclasts and promoting local growth factors, it therefore improves bone healing (Bayani et al) [2]. HA contains only calcium and phosphate ions, and therefore has no harmful local or systemic toxicity and that the high temperature used to prepare HA burns any organic molecules such as proteins that inhibit immune response and transplant rejection (Dorozhkin,) [8].…”

Section: Histologic Evaluation and Biocompatibilitymentioning

confidence: 99%

Preparing of Nano-Hydroxyapatite from Seashell and Mixed with Gold to Repair Bony Defect of Mandibular Bone in Rabbits

Taqa,

Al-Hussary,

Kashmola

2023

IJOIR

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The objectives of the present study were undertaken to prepared hydroxyapatite powder from seashell and convert this to nano size and then added to gold nanoparticles. Materials and Methods: The seashells was cleaned and the phosphoric acid was added. The product was inserted in oven then calcined in the muffled furnace, to evaporate CO2 and getting the white crystalline powder which indicated presence of hydroxyapatite. This powder was converted to nanoparticle. Gold 1% mixed with prepared seashell nano hydroxyapatite. The characteristics of the prepared nano hydroxyapatite from seashell, were studied by the FTIR infrared spectrophotometer. The most biocompatible nano hydroxyapatite estimation by chemical test and examine prepared nano hydroxyapatite from seashell alone or when mixed with gold 1% in vivo to detect the effectiveness on reparing bone defect in mandibulare rabbits. Results: The results of an infrared measurement (FTIR Spectroscopy) for prepared nano hydroxyapatite showed that the chemical structure and band have the same FTIR spectrum of standard nano hydroxyapatite and have the same nano traits as the chemical test showed a yellow precipitation consisting in the nHA seashells. As an indication of biocompatibility and increase Bone Mineral Density by repairing bone defect in rabbits. And when added gold to nano hydroxyapatite, increased the efficacy of bone remodeling and repair bone. Conclusions: The possibility of preparing nanoparticles for hydroxyapatite from seashell are simple and inexpensive feedstock's and can be successfully produced by chemical precipitation technology from seashells with a phosphoric acid solution.

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Injectable Functional Biomaterials for Minimally Invasive Surgery

Raucci

D’Amora

Ronca

et al. 2020

Adv Healthcare Materials

104

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Injectable materials represent very attractive ready‐to‐use biomaterials for application in minimally invasive surgical procedures. It is shown that this approach to treat, for example, vertebral fracture, craniofacial defects, or tumor resection has significant clinical potential in the biomedical field. In the last four decades, calcium phosphate cements have been widely used as injectable materials for orthopedic surgery due to their excellent properties in terms of biocompatibility and osteoconductivity. However, few clinical studies have demonstrated certain weaknesses of these cements, which include high viscosity, long degradation time, and difficulties being manipulated. To overcome these limitations, the use of sol‐gel technology has been investigated, which has shown good results for synthesis of injectable calcium phosphate‐based materials. In the last few decades, injectable hydrogels have gained increasing attention owing to their structural similarities with the extracellular matrix, easy process conditions, and potential applications in minimally invasive surgery. However, the need to protect cells during injection leads to the development of double network injectable hydrogels that are capable of being cross‐linked in situ. This review will provide the current state of the art and recent advances in the field of injectable biomaterials for minimally invasive surgery.

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Self-Setting Calcium Orthophosphate (CaPO4) Formulations

Cited by 6 publications

References 733 publications

Automatic computation of bone defective volume from tomographic images

Automatic computation of bone defective volume from tomographic images

Preparing of Nano-Hydroxyapatite from Seashell and Mixed with Gold to Repair Bony Defect of Mandibular Bone in Rabbits

Injectable Functional Biomaterials for Minimally Invasive Surgery

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