As healthcare systems evolve, achieving interoperability and seamless data exchange becomes paramount. The key component of the data exchange is terminology managed by the terminology server. During “Comparative Analysis of Clinical Terminology Servers: A Quest for an Improved Solution” research, we did not find a terminology server suitable for our criteria and decided to develop our own terminology server. This article delves into implementing the Common Terminology Services 2 (CTS2) standard on PostgreSQL, a robust open-source relational database. The discussion encompasses the intricacies of integrating CTS2 with PostgreSQL, exploring the challenges and solutions encountered during the process. Additionally, the article comprehensively maps this implementation to HL7 Fast Healthcare Interoperability Resources (FHIR), a widely adopted standard for healthcare data exchange. Readers will gain insights into the technical aspects of the implementation, practical considerations, and the potential impact on healthcare data management. This exploration aims to guide developers, healthcare IT professionals, and stakeholders in leveraging CTS2 on PostgreSQL while ensuring compatibility with HL7 FHIR resources, ultimately fostering improved interoperability in the dynamic landscape of healthcare data systems.