We consider theoretically a closed (zero-dimensional) semiconductor microcavity where confined vacuum photonic mode is coupled to electrons in valence band of the semiconductor. It is shown that vacuum-induced virtual electron transitions between valence and conduction bands result in renormalization of electron energy spectrum. As a consequence, vacuum-induced band gaps appear within the valence band. Calculated values of the band gaps are of sub-meV scale, that makes this QED effect to be measurable in state-of-the-art experiments.PACS numbers: 42.50. Pq, 42.50.Hz, 71.20.Mq Introduction.-There are physical situations where the electron-photon interaction cannot be considered as a weak perturbation (so-called regime of strong lightmatter coupling). In this regime, it is necessary to consider the system "electron + field" as a whole. Such a bound electron-photon object, which was called "electron dressed by field" (dressed electron), became commonly used model in modern physics [1,2]. The interest in this field is stimulated by the possibility of the achievement of the hybrid -half-light half-matter -excitations which can demonstrate peculiar properties. Therefore, the regime of strong light-matter coupling was extensively investigated both theoretically and experimentally in a variety of the systems, including optical planar microcavities with semiconductor [3-5] and organic [6][7][8] quantum wells, microcavities with individual quantum dots [9-11] and others. Effects of strong coupling can be used for variety of technological applications [12], including novel types of the lasers [13,14], optical switches and logic gates [15][16][17], all-optical integrated circuits [18], sources of entangled photon pairs [19] and others. Among most bright phenomena of strong light-matter coupling, we have to note the field-induced modification of energy spectrum of dressed electrons -also known as a dynamic (ac) Stark effect -which was discovered in atoms many years ago [20] and has been studied in details in various atomic and molecular systems [1,2]. For solids, the dynamic Stark effect results in the gap opening within electron energy bands [21][22][23][24][25].In order to turn usual "bare" electrons into "dressed" electrons, a characteristic energy of electron-photon interaction should be increased. This can be done in two different ways. The first of them consists in using a strong laser-generated electromagnetic field (the case of large photon occupation numbers) [1,2]. The second way consists in decreasing the effective volume where electron-