Seminal fluid features of male partners of infertility patients in southeast Nigeria

Ajah, Leonard Ogbonna; Ozumba, Benjamin C.; Onoh, Robinson Chukwudi; Ezeonu, Paul Olisaemeka; Iyoke, Chukwuemeka Anthony; Ezeome, Ijeoma Victoria

doi:10.4103/2384-5589.198320

Cited by 6 publications

(12 citation statements)

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“…Other parameters comprise sperm concentration of greater than or equal to 15 million sperm cells per mL, total sperm count of 39 million per ejaculate, progressive motility of 32% or more, vitality of 58% or more live spermatozoa, total motility of 40% and a morphology of 4% or more of normal forms. [6][7][8] The most common abnormality observed was asthenozoospermia, and only 44.2% of subjects had sperms with normal forward progressive motility, which is also similar to a study by Jeje et al that reported asthenozoospermia as the commonest semen abnormality. 2 Abnormal sperm motility is a major factor contributing to infertility, as the sperm will be unable to ascend the female genital tract for fertilization.…”

Section: Discussionsupporting

confidence: 80%

“…The frequency of azoospermia in this study is similar to 11.0% reported by Omo-Aghoja L et al in Niger delta region, but, slightly higher than 6.4% and 7.8% reported in Ibadan and Abakaliki, respectively. 5,1,7 The proportion of subjects with oligozoospermia in this study is less than the 32.1% reported by Ajah, et al, and 22.8% reported by Omo-Aghoja L et al, but similar to that of Adeniji et al where it accounted for 18.9% of the abnormal semen parameters. Furthermore, teratozoospermia accounts for 0.8% of our seminal fluid abnormalities unlike previous studies by Adeniji and Ajah et al who reported 6.5% and 8.4% respectively.…”

Section: 12-14contrasting

confidence: 44%

“…This is similar to 66.7% reported in Delta state but higher than 30% reported in Ibadan and Abakaliki. 1,5,7 The World Health Organization (WHO) in 2010 defined normal values for semen parameters as complete liquefaction within 60 minutes at room temperature, seminal volume of greater than or equal to 1.5 mL, and a pH greater than or equal to 7.2. Other parameters comprise sperm concentration of greater than or equal to 15 million sperm cells per mL, total sperm count of 39 million per ejaculate, progressive motility of 32% or more, vitality of 58% or more live spermatozoa, total motility of 40% and a morphology of 4% or more of normal forms.…”

Section: Discussionmentioning

confidence: 99%

“…2,5,6 This analysis includes semen volume and pH, microscopy for sperm concentration, count, motility, morphology, vitality, debris and agglutination and leucocyte count. 7 Seminal fluid analysis is generally inexpensive laboratory test, and the services are readily available in most fertility clinics. 2,5 It is therefore imperative to identify the causes of these abnormal seminal fluid parameters and to offer solutions early.…”

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confidence: 99%

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Seminal fluid parameters of male partners of infertile couples seeking care at the Lagos University Teaching Hospital

Makwe

Ugwu

Ojewola

et al. 2021

Int J Reprod Contracept Obstet Gynecol

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Background: Seminal fluid analysis is essential in the evaluation of the male partner of infertile couple. Available data suggest an increase in male-related factors among infertile couples seeking fertility treatment. Seminal fluid analysis performed using standardized methods can identify several causes of male-factor infertility. The latest World Health Organization (2010) guidelines for the laboratory examination and processing of human semen allows for standardization and identification of the possible causes of male-factor infertility. This study aimed to determine the pattern of seminal fluid analysis of male partners of infertile couple presenting to the fertility (gynaecological and urological) clinics of the Lagos University Teaching Hospital (LUTH).Methods: This was a retrospective study of the semen parameters of male partners of infertile couple that were evaluated at LUTH, from January 2018 to December 2019. The medical records of all male partners of infertile couples who had seminal fluid analysis were reviewed and the relevant seminal fluid parameters were collected using a standardized questionnaire.Results: A total of 604 male partners of couples with infertility sought fertility treatment during the study period. Out of the 604, 502 (83.1%) of the participants had complete seminal fluid result and these data were included in final analysis. The mean (SD) age of subjects was 42.1 (7.7) years. About three-quarter (73.1%) of the subjects have abnormal semen parameters. The most frequent semen abnormality was asthenozoospermia (55.8%) followed by oligozoospermia (39.4%).Conclusions: Male factor is still common cause of infertility among infertile couple seeking treatment in our environment.

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Section: Discussionsupporting

confidence: 80%

Section: 12-14contrasting

confidence: 44%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

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Seminal fluid parameters of male partners of infertile couples seeking care at the Lagos University Teaching Hospital

Makwe

Ugwu

Ojewola

et al. 2021

Int J Reprod Contracept Obstet Gynecol

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“…Considering the induction of addiction that is associated with long‐term use of opioids (Ghoneim, Khalaf, Elsamanoudy, & Helaly, ), it is difficult for these addicts to stay off the drug. All these pose threat to the male factor fertility in Nigeria, and previous report shows that male factor infertility in Nigeria is still rising (Ajah et al, ). The impairment in testicular function caused by tramadol has been associated with oxidative stress in the testis (Ghoneim et al, ; Nna & Osim, ).…”

Section: Introductionmentioning

confidence: 97%

Vitamin E administration does not ameliorate tramadol‐associated impairment of testicular function in Wistar rats

et al. 2019

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Tramadol is widely abused in Nigeria and has been reported to cause fertility decline via testicular oxidative stress. This study investigated the effect of vitamin E, an antioxidant on some reproductive parameters in male Wistar rats administered tramadol. Twenty male Wistar rats (180-200 g) were randomly assigned into four groups (n = 5) thus: Control (0.2 ml vehicle: olive oil), tramadol-treated (20 mg/kg of tramadol), vitamin E-treated (100 mg/kg of vitamin E) and tramadol + vitamin Etreated (received tramadol and vitamin E) groups. Drugs were administered orally and daily for 28 days. Sperm count, Johnsen's score, germinal epithelial height and serum testosterone, follicle-stimulating hormone (FSH) and luteinising hormone (LH) concentrations were significantly (p < .05) decreased in tramadol-treated and tramadol + vitamin E compared with control and vitamin E-treated groups. Sperm motility, morphology, viability, seminiferous tubular diameter, Leydig cell count, Sertoli cell count and malondialdehyde, superoxide dismutase, glutathione peroxidase and catalase concentrations were not significantly different among the groups. Histology of testis and epididymis in all groups showed no toxicity but decreased sperm population in tramadol-treated and tramadol + vitamin E-treated groups. Tramadol did not cause testicular oxidative stress but impaired testicular function by suppressing testosterone, FSH and LH secretion. Vitamin E administration could not attenuate this impairment in testicular function. K E Y W O R D S spermatogenesis, testis, testosterone, tramadol, vitamin E How to cite this article: Udefa AL, Beshel FN, Nwangwa JN, et al. Vitamin E administration does not ameliorate tramadolassociated impairment of testicular function in Wistar rats.

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A Study of Infertility Cases in Males in Basrah Province

Edan¹,

Mahdi²,

Alsaimary³

2023

UTJsci

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Infertility remains a global health challenge with devastating psycho-social consequences in many communities, and the underlying long-term risk of couple separation is also a major clinical and social problem. Infertility is defined as the inability of a couple to conceive naturally after one year of intercourse. A case-control study was carried out among males who have infertility and who attended the Infertility and in vitro fertilization Center of Basrah province in the period extended from September 2021 to June 2022. A questionnaire was used to record The special notes. Seminal fluid samples were collected from (176 patients and controls were divided into 88 patients of male samples and 88 samples of the control group). In the present study, age was divided into three groups, which were statistically non-significant. The residence was also non-significant, which included central and peripheral areas. The results also showed no statistical significance between smokers and nonsmokers. The laboratory results showed that the analyzed seminal fluid parameters such as volume, sperm count, grade A, grade D, and Morphology of sperm in the patient's group differed significantly from that of the control group (P. value <0.05). Compared to primary infertility (N=61,34.6%) or secondary infertility (N=27,15.4%), the analyzed seminal fluid parameters showed no statistical significance. In addition, the seminal fluid abnormalities, which were divided into six groups, that were found significantly statistically significant in patients from controls, include asthenozoospermia, necrozoospermia, teratozoospermia, and leukocytopenia. (P. value <0.05).

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Seminal fluid features of male partners of infertility patients in southeast Nigeria

Cited by 6 publications

References 1 publication

Seminal fluid parameters of male partners of infertile couples seeking care at the Lagos University Teaching Hospital

Seminal fluid parameters of male partners of infertile couples seeking care at the Lagos University Teaching Hospital

Vitamin E administration does not ameliorate tramadol‐associated impairment of testicular function in Wistar rats

A Study of Infertility Cases in Males in Basrah Province

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