2012
DOI: 10.1007/s40003-011-0006-2
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Seminal Plasma Proteome: Promising Biomarkers for Bull Fertility

Abstract: The seminal plasma is a mixture of secretions from the testis, epididymis and male accessory sex glands. A number of seminal plasma proteins are associated with male fertility but most of these have not been studied in detail till now. Recently, proteomics has been used to show the differences in proteins profile in seminal plasma from high and low fertility bulls. For example, osteopontin, phospholipase A2, P25b, acidic seminal fluid proteins, a-L-fucosidase and cathepsin D are positively correlated with fert… Show more

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Cited by 33 publications
(31 citation statements)
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“…While some speciic sperm protein markers facilitating good semen freezability have been identiied [10,24,39,40], their function depends on the presence of mRNA that can be translated into proteins in the spermatozoa. Moreover, the diferential expression paterns of certain classes of SP and sperm proteins following cryopreservation have been used as markers for semen freezability [3,6,10,[39][40][41][42][43][44]. Regarding boar semen, the physiological functions of SP and sperm proteins and their associations with freezability have been summarized in recent reviews by Yeste [3,10].…”
Section: Protein Freezability Markersmentioning
confidence: 99%
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“…While some speciic sperm protein markers facilitating good semen freezability have been identiied [10,24,39,40], their function depends on the presence of mRNA that can be translated into proteins in the spermatozoa. Moreover, the diferential expression paterns of certain classes of SP and sperm proteins following cryopreservation have been used as markers for semen freezability [3,6,10,[39][40][41][42][43][44]. Regarding boar semen, the physiological functions of SP and sperm proteins and their associations with freezability have been summarized in recent reviews by Yeste [3,10].…”
Section: Protein Freezability Markersmentioning
confidence: 99%
“…Regarding boar semen, the physiological functions of SP and sperm proteins and their associations with freezability have been summarized in recent reviews by Yeste [3,10]. In the bull, higher concentrations of a 26-kDa SP protein, known as lipocalin-type prostaglandin D synthase (L-PGDS), and a 13-kDa acidic seminal luid protein (aSFP) were associated with high-fertility bulls, suggesting the importance of these proteins as freezability markers [41]. Moreover, a fertilityassociated protein, osteopontin (OPN), an acidic glycoprotein occurring in the bovine SP, has been shown to induce capacitation and improve viability of spermatozoa by inhibiting the apoptotic pathways [39,41].…”
Section: Protein Freezability Markersmentioning
confidence: 99%
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