Sensitive and selective surface plasmon resonance sensor employing a gold-supported graphene composite film/D-shaped fiber for dopamine detection

Sun, Junxia; Jiang, Shouzhen; Xu, Jihua; Li, Zhen; Li, Chonghui; Yu, Jing; Zhao, Xiaofei; Pan, Jie; Zhang, Chao; Man, Baoyuan

doi:10.1088/1361-6463/ab08c1

Cited by 31 publications

(14 citation statements)

References 42 publications

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“…N. Cennamo et al investigated the effects of different photoresist buffer layers on the POF-based SPR sensor performance [ 25 ], and a POF-SPR-based magnetic field sensor [ 26 ] and a fluorescent POF-based SPR sensor [ 27 ] were also proposed by the same group. In addition, a gold-supported graphene composite film-coated POF-based SPR sensor for dopamine detection was also reported [ 28 ]. The recent developments of the POFs-based SPR sensors have demonstrated that they are playing a more and more important role in the SPR sensing fields.…”

Section: Introductionmentioning

confidence: 99%

An Enhanced Plastic Optical Fiber-Based Surface Plasmon Resonance Sensor with a Double-Sided Polished Structure

Liu

Deng

Zheng

et al. 2021

Sensors

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An enhanced plastic optical fiber (POF)-based surface plasmon resonance (SPR) sensor is proposed by employing a double-sided polished structure. The sensor is fabricated by polishing two sides of the POF symmetrically along with the fiber axis, and a layer of Au film is deposited on each side of the polished region. The SPR can be excited on both polished surfaces with Au film coating, and the number of light reflections will be increased by using this structure. The simulation and experimental results show that the proposed sensor has an enhanced SPR effect. The visibility and full width at half maximum (FWHM) of spectrum can be improved for the high measured refractive index (RI). A sensitivity of 4284.8 nm/RIU is obtained for the double-sided POF-based SPR sensor when the measured liquid RI is 1.42. The proposed SPR sensor is easy fabrication and low cost, which can provide a larger measurement range and action area to the measured samples, and it has potential application prospects in the oil industry and biochemical sensing fields.

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Section: Introductionmentioning

confidence: 99%

An Enhanced Plastic Optical Fiber-Based Surface Plasmon Resonance Sensor with a Double-Sided Polished Structure

Liu

Deng

Zheng

et al. 2021

Sensors

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“…In extrinsic fiber sensors, optical fibers are used only to connect a sensing region with a light source and a detector. Up to now, intrinsic and extrinsic fiber-optic SPR sensors have been realized for sensing in environmental, security, industrial, biomedical, and biochemical sectors, detecting from small chemical compounds to more complex biological molecules such as proteins [20][21][22][23][24].…”

Section: Introductionmentioning

confidence: 99%

Bovine Serum Albumin Protein Detection by a Removable SPR Chip Combined with a Specific MIP Receptor

et al. 2021

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Nowadays, the development of simple, fast, and low-cost selective sensors to detect substances of interest is of great importance in several application fields. Among this kind of sensors, those based on surface plasmon resonance (SPR) represent a promising category, since they are highly sensitive, versatile, and label-free. In this work, an SPR probe, based on a poly(methyl methacrylate) (PMMA) slab waveguide covered by a gold nanofilm, combined with a specific molecularly imprinted polymer (MIP) receptor for bovine serum albumin (BSA) protein, has been realized and experimentally characterized. The obtained experimental results have shown a limit of detection (LOD) equal to about 8.5 × 10−9 M. This value is smaller than the one achieved by another SPR probe, based on a D-shaped plastic optical fiber (POF), functionalized with the same MIP receptor; more specifically, the obtained LOD was reduced by about three orders of magnitude with respect to the POF configuration. Moreover, concerning the D-shaped POF configuration, no manufacturing process is present in the proposed sensor configuration. In addition, fibers are used only to connect the simple sensor chip with a light source and a detector, promoting a bio-chemical sensing approach based on disposable, low-cost, and removable chips.

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“…They demonstrated that graphene enhanced the sensitivity and played a role in amplification of the SPR signal by introducing DBA. They demonstrated the potential of this sensor to detect DA-induced disorders [ 136 ]. Graphene improved the sensor sensitivity and amplified the SPR signal.…”

Section: Da Detection Using Spr Biosensorsmentioning

confidence: 99%

The Principle of Nanomaterials Based Surface Plasmon Resonance Biosensors and Its Potential for Dopamine Detection

Eddin

Fen

2020

Molecules

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For a healthy life, the human biological system should work in order. Scheduled lifestyle and lack of nutrients usually lead to fluctuations in the biological entities levels such as neurotransmitters (NTs), proteins, and hormones, which in turns put the human health in risk. Dopamine (DA) is an extremely important catecholamine NT distributed in the central nervous system. Its level in the body controls the function of human metabolism, central nervous, renal, hormonal, and cardiovascular systems. It is closely related to the major domains of human cognition, feeling, and human desires, as well as learning. Several neurological disorders such as schizophrenia and Parkinson’s disease are related to the extreme abnormalities in DA levels. Therefore, the development of an accurate, effective, and highly sensitive method for rapid determination of DA concentrations is desired. Up to now, different methods have been reported for DA detection such as electrochemical strategies, high-performance liquid chromatography, colorimetry, and capillary electrophoresis mass spectrometry. However, most of them have some limitations. Surface plasmon resonance (SPR) spectroscopy was widely used in biosensing. However, its use to detect NTs is still growing and has fascinated impressive attention of the scientific community. The focus in this concise review paper will be on the principle of SPR sensors and its operation mechanism, the factors that affect the sensor performance. The efficiency of SPR biosensors to detect several clinically related analytes will be mentioned. DA functions in the human body will be explained. Additionally, this review will cover the incorporation of nanomaterials into SPR biosensors and its potential for DA sensing with mention to its advantages and disadvantages.

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Sensitive and selective surface plasmon resonance sensor employing a gold-supported graphene composite film/D-shaped fiber for dopamine detection

Cited by 31 publications

References 42 publications

An Enhanced Plastic Optical Fiber-Based Surface Plasmon Resonance Sensor with a Double-Sided Polished Structure

An Enhanced Plastic Optical Fiber-Based Surface Plasmon Resonance Sensor with a Double-Sided Polished Structure

Bovine Serum Albumin Protein Detection by a Removable SPR Chip Combined with a Specific MIP Receptor

The Principle of Nanomaterials Based Surface Plasmon Resonance Biosensors and Its Potential for Dopamine Detection

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