Sensitive colorimetric detection of ochratoxin A by a dual-functional Au/Fe<sub>3</sub>O<sub>4</sub> nanohybrid-based aptasensor

Huang, Rong; Xiong, Lu; Chai, Hui; Fu, Jing; Lu, Zhisong

doi:10.1039/c9ra07899a

Cited by 14 publications

(3 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…On the contrary, a strong and specific interaction between aptamers and OTA reduces the shielding effect, leading to a dose−dependent fluorescence decrease ( Figure 1 A) [ 28 ]. The same principle is applied to the BAS based on Au/Fe 3 O 4 and the BAS based on GO; the former’s SA is labeled by alkaline phosphatase ( Figure 1 B) [ 29 ], and the latter’s SA is not labeled ( Figure 1 C) [ 30 ].…”

Section: Aptamer Conjugation Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Advances in Aptamer-Based Conjugate Recognition Techniques for the Detection of Small Molecules in Food

Deng,

Ma,

Gong

et al. 2024

Foods

View full text Add to dashboard Cite

Small molecules are significant risk factors for causing food safety issues, posing serious threats to human health. Sensitive screening for hazards is beneficial for enhancing public security. However, traditional detection methods are unable to meet the requirements for the field screening of small molecules. Therefore, it is necessary to develop applicable methods with high levels of sensitivity and specificity to identify the small molecules. Aptamers are short−chain nucleic acids that can specifically bind to small molecules. By utilizing aptamers to enhance the performance of recognition technology, it is possible to achieve high selectivity and sensitivity levels when detecting small molecules. There have been several varieties of aptamer target recognition techniques developed to improve the ability to detect small molecules in recent years. This review focuses on the principles of detection platforms, classifies the conjugating methods between small molecules and aptamers, summarizes advancements in aptamer−based conjugate recognition techniques for the detection of small molecules in food, and seeks to provide emerging powerful tools in the field of point−of−care diagnostics.

show abstract

Section: Aptamer Conjugation Methodsmentioning

confidence: 99%

“…( B ) The detection of ochratoxin A in peanut, corn, and wine. Reproduced from [ 29 ]. ( C ) The detection of chloramphenicol in honey.…”

Section: Figurementioning

confidence: 99%

Advances in Aptamer-Based Conjugate Recognition Techniques for the Detection of Small Molecules in Food

Deng,

Ma,

Gong

et al. 2024

Foods

View full text Add to dashboard Cite

show abstract

“…Visual detection was realized with a low LOD of 0.3 ng/ml for FB 1 . Based on the alkaline phosphatase (ALP) catalyzed color change and the magneto-controlled fast separation, Huang, Xiong, et al (2019) developed a CM aptasensor for OTA detection. Aptamer acted as the shielding cap to cover the biotin and block the specific interaction between the biotin and the ALP-labeled streptavidin (SA-ALP).…”

Section: Aptasensorsmentioning

confidence: 99%

Aptasensors for mycotoxins in foods: Recent advances and future trends

Hou

Jia

Sheng

et al. 2021

Comp Rev Food Sci Food Safe

View full text Add to dashboard Cite

Mycotoxin contamination in foods has posed serious threat to public health and raised worldwide concern. The development of simple, rapid, facile, and cost‐effective methods for mycotoxin detection is of urgent need. Aptamer‐based sensors, abbreviated as aptasensors, with excellent recognition capacity to a wide variety of mycotoxins have attracted ever‐increasing interest of researchers because of their simple fabrication, rapid response, high sensitivity, low cost, and easy adaptability for in situ measurement. The past few decades have witnessed the rapid advances of aptasensors for mycotoxin detection in foods. Therefore, this review first summarizes the reported aptamer sequences specific for mycotoxins. Then, the recent 5‐year advancements in various newly developed aptasensors, which, according to the signal output mode, are divided into electrochemical, optical and photoelectrochemical categories, for mycotoxin detection are comprehensively discussed. A special attention is taken on their strengths and limitations in real‐world application. Finally, the current challenges and future perspectives for developing novel highly reliable aptasensors for mycotoxin detection are highlighted, which is expected to provide powerful references for their thorough research and extended applications. Owing to their unique advantages, aptasensors display a fascinating prospect in food field for safety inspection and risk assessment.

show abstract

Nanomaterial-based aptamer biosensors for ochratoxin A detection: a review

et al. 2022

View full text Add to dashboard Cite

Sensitive colorimetric detection of ochratoxin A by a dual-functional Au/Fe₃O₄ nanohybrid-based aptasensor

Abstract: A novel colorimetric aptasensor based on a Au/Fe3O4 nanohybrid was developed to detect ochratoxin A (OTA).

Cited by 14 publications

References 38 publications

Advances in Aptamer-Based Conjugate Recognition Techniques for the Detection of Small Molecules in Food

Advances in Aptamer-Based Conjugate Recognition Techniques for the Detection of Small Molecules in Food

Aptasensors for mycotoxins in foods: Recent advances and future trends

Nanomaterial-based aptamer biosensors for ochratoxin A detection: a review

Contact Info

Product

Resources

About

Sensitive colorimetric detection of ochratoxin A by a dual-functional Au/Fe3O4 nanohybrid-based aptasensor

Abstract: A novel colorimetric aptasensor based on a Au/Fe3O4 nanohybrid was developed to detect ochratoxin A (OTA).

Cited by 14 publications

References 38 publications

Advances in Aptamer-Based Conjugate Recognition Techniques for the Detection of Small Molecules in Food

Advances in Aptamer-Based Conjugate Recognition Techniques for the Detection of Small Molecules in Food

Aptasensors for mycotoxins in foods: Recent advances and future trends

Nanomaterial-based aptamer biosensors for ochratoxin A detection: a review

Contact Info

Product

Resources

About

Sensitive colorimetric detection of ochratoxin A by a dual-functional Au/Fe₃O₄ nanohybrid-based aptasensor