Sensitive Electrochemical Detection Method of Melatonin in Food Supplements

Miccoli, Angela; Restani, Patrizia; Floroian, Laura; Taus, Nicoleta; Badea, Mihaela; Cioca, Gabriela; Bungău, Simona

doi:10.37358/rc.18.4.6215

Cited by 16 publications

(11 citation statements)

References 35 publications

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“…A very similar approach was reported by Miccoli et al [ 161 ] to detect MLT in food supplements using differential pulse voltammetry (DPV) with a G-CSPE. Graphene was suspended, and the electrodes were modified by drop-casting.…”

Section: Graphene-based Sensors For Bioactive Compoundsmentioning

confidence: 90%

Graphene-Based Sensors for the Detection of Bioactive Compounds: A Review

Sainz-Urruela

Vera

Andrés

et al. 2021

IJMS

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Over the last years, different nanomaterials have been investigated to design highly selective and sensitive sensors, reaching nano/picomolar concentrations of biomolecules, which is crucial for medical sciences and the healthcare industry in order to assess physiological and metabolic parameters. The discovery of graphene (G) has unexpectedly impulsed research on developing cost-effective electrode materials owed to its unique physical and chemical properties, including high specific surface area, elevated carrier mobility, exceptional electrical and thermal conductivity, strong stiffness and strength combined with flexibility and optical transparency. G and its derivatives, including graphene oxide (GO) and reduced graphene oxide (rGO), are becoming an important class of nanomaterials in the area of optical and electrochemical sensors. The presence of oxygenated functional groups makes GO nanosheets amphiphilic, facilitating chemical functionalization. G-based nanomaterials can be easily combined with different types of inorganic nanoparticles, including metals and metal oxides, quantum dots, organic polymers, and biomolecules, to yield a wide range of nanocomposites with enhanced sensitivity for sensor applications. This review provides an overview of recent research on G-based nanocomposites for the detection of bioactive compounds, providing insights on the unique advantages offered by G and its derivatives. Their synthesis process, functionalization routes, and main properties are summarized, and the main challenges are also discussed. The antioxidants selected for this review are melatonin, gallic acid, tannic acid, resveratrol, oleuropein, hydroxytyrosol, tocopherol, ascorbic acid, and curcumin. They were chosen owed to their beneficial properties for human health, including antibiotic, antiviral, cardiovascular protector, anticancer, anti-inflammatory, cytoprotective, neuroprotective, antiageing, antidegenerative, and antiallergic capacity. The sensitivity and selectivity of G-based electrochemical and fluorescent sensors are also examined. Finally, the future outlook for the development of G-based sensors for this type of biocompounds is outlined.

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Section: Graphene-based Sensors For Bioactive Compoundsmentioning

confidence: 90%

Graphene-Based Sensors for the Detection of Bioactive Compounds: A Review

Sainz-Urruela

Vera

Andrés

et al. 2021

IJMS

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“…From the results showed above is deducted that by the two types of electrochemical methods using screenprinted carbon electrodes (DPV and CV) and Jenco microelectrodes (for iodide detection), iodide can be easily determined qualitatively and quantitatively. Both methods are safe and easy to use, and can be thought of as a portable system with a wide range of applicability [34][35][36][37][38][39][40] (screen electrodes are already used to detect toxic and bioactive compounds in the life sciences), alongside other validated methods for the same purpose [41][42][43][44][45][46][47]. Redox microelectrodes correlate in a good manner the redox status of the solution with KI concentration.…”

Section: B2 Redox Microelectrodementioning

confidence: 99%

New Electrochemical Detection Strategies for Iodinated Compounds

Chelmea¹,

Modugno²,

Samota³

et al. 2019

Rev. Chim.

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Iodine is a micronutrient of high importance for the health and good development of individuals. It is contained in many foods, but it is also part of the chemical component of oceans and soil. Its deficiency is still a problem of humanity, which has a serious repercussion on our health. It is therefore important to have specific, fast and cost effective methods of iodine detection from different samples. This work aims to identify optimal parameters for potassium iodide (KI) detection from different media, to be further applied to real samples: plant extracts, water, biological fluids. Results showed a significant difference in electrochemical results, depending on the pH values of the mixture and also on the time which influences the compounds stability. Differential pulse voltammetry and cyclic voltammetry using carbon printed sensors, as well as microsensors for redox status or direct iodide detection are important analytical tools which have a wide range of applications in the food, medicine, toxicology and other domains.

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“…Graphene sheets horizontal and vertical oriented on working electrode affects the electrochemical performance, evidenced by this study. Moreover, the comparison between single layer graphene and vertical graphene is an essential step for applications, so in function of application we can chose the graphene type [7].…”

Section: Introductionmentioning

confidence: 99%

Single Layer Graphene and Vertical Graphene as a Promising Candidate for Electrochemical Biosensors

Ţîncu¹,

Avram²,

Ţucureanu³

et al. 2020

Rev. Chim.

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Recently, graphene as a material for sensors has attracted attention due to unique properties, such as: excellent electrical and thermal conductivity, chemical stability, high surface area and Young�s modulus ̴ 1GPa, very promising for electrochemical applications. Electrochemical sensors based on graphene have been used in many applications, such as: biomolecules, gases or metal ions detection. Here, we report the effect of morphology and orientation of graphene as electrode material with electrochemical method. We investigated the capacitive performance in the case of horizontal and vertical graphene sheets, synthetized by thermal chemical vapor deposition (CVD), respectively plasma enhanced chemical vapor deposition (PECVD). Graphene electrode is used in electrochemical cells with three electrodes as a working electrode. Raman spectroscopy was carried on the graphene films for quality and structure characterization. The working electrode was characterized by scanning electron microscopy (SEM), Raman spectroscopy and electrochemical method.

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Sensitive Electrochemical Detection Method of Melatonin in Food Supplements

Cited by 16 publications

References 35 publications

Graphene-Based Sensors for the Detection of Bioactive Compounds: A Review

Graphene-Based Sensors for the Detection of Bioactive Compounds: A Review

New Electrochemical Detection Strategies for Iodinated Compounds

Single Layer Graphene and Vertical Graphene as a Promising Candidate for Electrochemical Biosensors

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