2021
DOI: 10.1007/s00604-021-05092-6
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Sensitive sandwich-type electrochemical SARS-CoV‑2 nucleocapsid protein immunosensor

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Cited by 62 publications
(31 citation statements)
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“…In the past three years, several electrochemical biosensors have been developed for detecting SARS-CoV-2 antigens based on diverse modified electrodes [25] , [26] , [27] , [28] , [29] . Despite such successes, the majority of these strategies either require sophisticated fabrication of an electrochemically responsive interface or synthesis of electroactive labels that link to bioreceptors [30] , [31] , or suffer from potential cross-reactivity of SARS-CoV-2 antibodies with antibodies generated against other coronaviruses due to their high genome similarities [32] , [33] , [34] , [35] . These drawbacks thereby result in potential tradeoffs in terms of sensitivity, specificity and user-friendliness.…”
Section: Introductionmentioning
confidence: 99%
“…In the past three years, several electrochemical biosensors have been developed for detecting SARS-CoV-2 antigens based on diverse modified electrodes [25] , [26] , [27] , [28] , [29] . Despite such successes, the majority of these strategies either require sophisticated fabrication of an electrochemically responsive interface or synthesis of electroactive labels that link to bioreceptors [30] , [31] , or suffer from potential cross-reactivity of SARS-CoV-2 antibodies with antibodies generated against other coronaviruses due to their high genome similarities [32] , [33] , [34] , [35] . These drawbacks thereby result in potential tradeoffs in terms of sensitivity, specificity and user-friendliness.…”
Section: Introductionmentioning
confidence: 99%
“…EIS is also an effective tool to characterize the electrochemical properties of the modified electrodes. 44 EIS measurements were obtained with different modified electrodes in 5.0 mM [Fe(CN) 6 ] 3−/4− solution containing 0.1 M KCl ( Fig. 3b ).…”
Section: Resultsmentioning
confidence: 99%
“…The experimental procedure is discussed in the ESI. † 60,61 The recovery data was calculated using eqn (S1). † The outcome revealed satisfactory recoveries (99.8% to 100.1%) as shown in Table S2.…”
Section: Real Sample Analysis On the Designed Porphyrin/fe 2 O 3 @Ni ...mentioning
confidence: 99%