Sensitive Simultaneous Determination of Rutin and Folic Acid with the Use of a Solid Lead Electrode by Means of Adsorptive Stripping Voltammetry

Abstract

In this article a solid lead electrode (PbE) was utilized for the first time for determination of organic substances by means of adsorptive stripping voltammetry. A new procedure of simultaneous determination of rutin and folic acid was developed. Two well shaped and well separated reduction signals of rutin and folic acid were obtained with the use of PbE. The optimization of analytical procedure was presented. The calibration graphs for rutin and folic acid for an accumulation time of 120 s were linear in the ranges from 2×10−9 to 1×10−7 mol L−1 and from 2×10−9 to 5×10−8 mol L−1, respectively. The obtained detection limits for rutin and folic acid determination following accumulation time of 120 s were 7.9×10−10 and 8.4×10−10 mol L−1. Potential interference effects were investigated. The proposed procedure was used for analysis of pharmaceutical preparations with satisfactory results showing practical applications. The analytical parameters of the proposed procedure were compared with other voltammetric procedures of mentioned substances determination.

Sensitive Determination of Folic Acid using a Solid Bismuth Microelectrode by Adsorptive Stripping Voltammetry

“…Solid metallic electrodes are an useful voltammetric tool as there is no need to add ions of a given metal to the supporting electrolyte in order to an electrochemical film plating during their application [46,47]. A continuation of our research are investigations on miniaturization of the proposed sensors and construction of solid metal microelectrodes for which preparation a very small amounts of electrode material are necessary.…”

Application of a Solid Bismuth Microelectrode in an Adsorptive Stripping Voltammetric Procedure of Trace Tin Quantification

“…In order to surmount this disadvantage, a solid bismuth electrode for voltammetric measurements was proposed. 6 However, comparatively large metallic bismuth foil (with a mass of about 10 mg) was used for the preparation of the above-mentioned electrode. Therefore, an attempt was made to miniaturize the solid bismuth electrodes, which resulted in the construction of a solid bismuth microelectrode, for the formation of which very small amounts of electrode material are needed.…”