Sensitivity and figure-of-merit enhancements of liquid-prism SPR sensor in the angular interrogation

2D Nanomaterial-Based Surface Plasmon Resonance Sensors for Biosensing Applications

“…This concept also showed high merit figures, and brought the benefits of reduced sample volume, as well as the ability to easily change the refractive liquid prism index by adjusting the reservoir of liquid prisms. Through the advent of new manufacturing methods, such as three-dimensional printing, a larger range of materials (e.g., glass, plastics) and revolutionary technologies would eventually lead the world to rethink how optical and instrumental design is performed [ 139 , 140 , 141 , 142 ].…”

Surface Plasmon Resonance: Material and Interface Design for Universal Accessibility

“…Song and co-workers have proposed the use of liquid prisms over solid prisms of glass or plastic. 105,106 In one design, a silver SPR chip was placed within a liquid reservoir that functioned as both the measurement cell and light coupler, with the metallic face of the chip sealed within an inert gas chamber to prevent oxidation and sample interference. 105 In contrast with traditional SPR sensors, increases in the sample refractive index led to decreases in resonance angle, which responded in a negative linear fashion.…”

“…Early efforts toward this goal utilized low refractive index glass and polymer prisms, each demonstrating enhanced SPR sensitivity over higher refractive index glass prisms, though these materials have yet to catch on with the wider SPR community. Song and co-workers have proposed the use of liquid prisms over solid prisms of glass or plastic. , In one design, a silver SPR chip was placed within a liquid reservoir that functioned as both the measurement cell and light coupler, with the metallic face of the chip sealed within an inert gas chamber to prevent oxidation and sample interference . In contrast with traditional SPR sensors, increases in the sample refractive index led to decreases in resonance angle, which responded in a negative linear fashion.…”

Research on Tunable SPR Sensors Based on WS2 and Graphene Hybrid Nanosheets

“…Part of the polarized light penetrates the metal and becomes an evanescent wave with exponential attenuation. When two wave vectors are coordinated, the immediate result is a sharp decrease in the energy of the detected reflected light, because the energy in the photons has been transferred in the process [2]. SPR-based biosensors are currently the focus of numerous studies due to the fact of their nondestructive inspection without specific markers for high-accuracy work requirements online, showing great potential in drug screening [3,4], environmental monitoring [5,6], biochemistry [7], and other fields.…”