Sensitivity enhancement for evanescent wave-excited fiber optic fluorescent sensors

Thompson, Richard B.; Kondracki, Lynne M.

doi:10.1117/12.17684

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Cited by 7 publications

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“…7 Secondly, in signal acquisition, there is only a low coupling efficiency of the fluorescence signal back to the fiber itself. 8 Thus, there is a critical need for optimum design and fabrication of the fiber-based optical sensor leading to high excitations and a high level of fluorescence signal acquisition at the output end of the fiber.…”

Section: Introductionmentioning

confidence: 99%

Optimum taper length for maximum fluorescence signal from an evanescent wave fiber optic biosensor

Sun

Kapoor

2008

Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications VIII

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A theoretical model using ray tracing method is developed. The results predicted by the model were confirmed by experimental results. The model could explain the experimentally observed fact that the maximum signal for a given realistic tapered length is at a probe radius smaller than that expected from V-number matching condition. It is shown that for obtaining maximum fluorescence signal from an evanescent wave fiber optic biosensor a realistic optimum taper length needs to be chosen. We found that different detection environments require different taper lengths at a given taper angle. These facts were confirmed experimentally.

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Section: Introductionmentioning

confidence: 99%