Sensory memory during physiological aging indexed by mismatch negativity (MMN)

Ruzzoli, Manuela; Pirulli, Cornelia; Brignani, Debora; Maioli, Claudio; Miniussi, Carlo

doi:10.1016/j.neurobiolaging.2011.03.021

Cited by 55 publications

(60 citation statements)

References 65 publications

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“…As could be expected from the inhibitory deficit hypothesis, older adults are more distracted by irregular deviant stimuli than younger adults [46,15,39,61]. The analysis of the deviant-related ERPs revealed that different cognitive subprocesses contribute to this increase in distractibility, comprising deficits in encoding or retention of sensory information [1,9,15,17,42,54,61] and in attentional orienting [18,28,46,39].…”

Section: Introductionmentioning

confidence: 67%

“…The analysis of the deviant-related ERPs revealed that different cognitive subprocesses contribute to this increase in distractibility, comprising deficits in encoding or retention of sensory information [1,9,15,17,42,54,61] and in attentional orienting [18,28,46,39]. Also, a delayed and incomplete re-orientation of attention to the relevant stimulus feature has been observed [46,39,31,32].…”

Section: Introductionmentioning

confidence: 98%

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ERP correlates of auditory goal-directed behavior of younger and older adults in a dynamic speech perception task

Getzmann

Falkenstein

Wascher

2015

Behavioural Brain Research

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Section: Introductionmentioning

confidence: 67%

Section: Introductionmentioning

confidence: 98%

ERP correlates of auditory goal-directed behavior of younger and older adults in a dynamic speech perception task

Getzmann

Falkenstein

Wascher

2015

Behavioural Brain Research

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“…These age changes correlated to a decline of sensory memory maintenance, interestingly, its encoding was relatively preserved (Ruzzoli, Pirulli, Brignani, Maioli, & Miniussi, 2012). For this reason some studies using a short interstimulus interval (less than 2 sec) showed little effect of age on the aMMN (Cheng et al, 2013).…”

Section: Summary In Aging and Maturationmentioning

confidence: 98%

Visual mismatch negativity (vMMN): A review and meta-analysis of studies in psychiatric and neurological disorders

Kremláček

Kreegipuu

Tales

et al. 2016

Cortex

122

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The visual mismatch negativity (vMMN) response is an event-related potential (ERP) component, which is automatically elicited by events that violate predictions based on prior events. VMMN experiments use visual stimulus repetition to induce predictions, and vMMN is obtained by subtracting the response to rare unpredicted stimuli from those to frequent stimuli. One increasingly popular interpretation of the mismatch response postulates that vMMN, similar to its auditory counterpart (aMMN), represents a prediction error response generated by cortical mechanisms forming probabilistic representations of sensory signals. Here we discuss the physiological and theoretical basis of vMMN and review thirty-three studies from the emerging field of its clinical applications, presenting a meta-analysis of findings in schizophrenia, mood disorders, substance abuse, neurodegenerative disorders, developmental disorders, deafness, panic disorder and hypertension. Furthermore, we include reports on aging and maturation as they bear upon many clinically relevant conditions. Surveying the literature we found that vMMN is altered in several clinical populations which is in line with aMMN findings. An important potential advantage of vMMN however is that it allows the investigation of deficits in predictive processing in cognitive domains which rely primarily on visual information; a principal sensory modality and thus of vital importance in environmental information processing and response, and a modality which arguably may be more sensitive to some pathological changes. However, due to the relative infancy of research in vMMN compared to aMMN in clinical populations its potential for clinical application is not yet fully appreciated. The aim of this review and meta-analysis therefore is to present, in a detailed systematic manner, the findings from clinically-based vMMN studies, to discuss their potential impact and application, to raise awareness of this measure and to improve our understanding of disease upon fundamental aspects of visual information processing. Furthermore, we include reports on aging and maturation as they bear upon many clinically relevant conditions. Surveying the literature we found that vMMN is altered in several 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 clinical populations which is in line with aMMN findings. An important potential advantage of vMMN however is that it allows the investigation of deficits in predictive processing in cognitive domains which rely primarily on visual information; a principal sensor...

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“…With increasing age, the brain undergoes changes in structure, neurochemistry and electrophysiology as well as the dysfunction of inhibitory neurotransmitter γ-aminobutyric acid receptors and increases in excitatory neurotransmitters and glutamate and N-methyl-D -aspartate receptors. All of these changes can affect central synergistic activity and related functions, such as sensory memory [Ruzzoli et al, 2012]. In the presence of background noise, cortical neurons in the elderly cannot effectively process auditory information.…”

Section: Aging Interferes With Preattentive Central Auditory Processimentioning

confidence: 99%

The Effect of Aging and the High-Frequency Auditory Threshold on Speech-Evoked Mismatch Negativity in a Noisy Background

Chen

Chen²,

Zheng³

et al. 2015

Audiol Neurotol

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Mismatch negativity (MMN) has been widely used to study the function of central auditory processing in the elderly. However, current research has not yet considered the effect of noise and high-frequency hearing threshold on MMN in the elderly. The aim of this study was to evaluate the effect of aging and high-frequency hearing loss on speech-related MMN in noisy backgrounds. Additionally, the possible mechanisms of central auditory processing dysfunction in the elderly were investigated. Fifty people aged 61-80 (70 ± 5.8) years were recruited for this study. They were divided into a 61- to 70-year-old group and a 71- to 80-year-old group. Fifty younger adults aged 21-40 (31 ± 5.3) years were recruited as healthy controls. Pure-tone hearing thresholds were recorded. A speech discrimination score (SDS) and a speech-evoked MMN under white noise with a bandwidth from 125 to 8,000 Hz background condition were recorded. The relationships between SDS and MMN latency and amplitude were analyzed. The effects of age and binaural 2,000-, 4,000- and 8,000-Hz pure-tone hearing thresholds on MMN latency and amplitude were analyzed. We found that the hearing thresholds of 2,000, 4,000 and 8,000 Hz in the 61- to 70-year-old and 71- to 80-year-old groups were higher than those in the control group. The SDS in a noisy background in the 61- to 70-year-old and 71- to 80-year-old groups were lower than those in the control group. Speech-evoked MMN latency was longer in the 61- to 70-year-old and in the 71- to 80-year-old groups than in the control group (215.8 ± 14.2 ms). SDS and speech-evoked MMN latency were negatively correlated. Age and speech-evoked MMN latency were positively correlated, as were the binaural 4,000- to 8,000-Hz pure-tone hearing thresholds and speech-evoked MMN. This study suggests that in elderly subjects, the function of preattentive central auditory processing changes. Additionally, increasing age and high-frequency hearing thresholds create a synergy in neurons that is weakened in the MMN time window, which may be a cause of central auditory processing disorders in elderly subjects in noisy background conditions.

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Sensory memory during physiological aging indexed by mismatch negativity (MMN)

Cited by 55 publications

References 65 publications

ERP correlates of auditory goal-directed behavior of younger and older adults in a dynamic speech perception task

ERP correlates of auditory goal-directed behavior of younger and older adults in a dynamic speech perception task

Visual mismatch negativity (vMMN): A review and meta-analysis of studies in psychiatric and neurological disorders

The Effect of Aging and the High-Frequency Auditory Threshold on Speech-Evoked Mismatch Negativity in a Noisy Background

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