Sentinel Lymph Node Biopsy is Associated with Improved Survival in Merkel Cell Carcinoma

Abstract

SNB for MCC provides prognostic information and is associated with a significant survival advantage.

The Influence of Sentinel Lymph Node Biopsy on Survival for Intermediate-Thickness Melanoma

“…17 The SEER registry allows us to acquire an adequate population that can answer a question that may be difficult to answer using a randomized control trial. [34][35][36] Because SNB has significant financial costs and potential postoperative complications, further studies are required to assess the clinical effectiveness of SNB for intermediatethickness melanoma. 37 Currently the MSLT-II trail is attempting to answer this question by randomizing patients with established sentinel lymph node disease to either undergo immediate CLND or nodal observation.…”

Lymphatic mapping and sentinel node biopsy in a patient with upper limb Merkel Cell Carcinoma: a case report and brief review of literature

“…Thus far, six studies reported survival benefit of sentinel node mapping in cN0 MCC patients [20][21][22][23][24][25]. Table 1 summarizes the characteristics of these studies in addition to their main prognostic findings.…”

Sentinel Lymph Node Biopsy for Eyelid and Conjunctival Tumors

“…82 The SLN positivity rate for MCC in all anatomic locations falls between 24% and 48%. 86,87 Some authors assert that SLN mapping can improve disease-free survival by significantly lowering recurrence rates compared with nodal observation. 88,89 The number of involved nodes has been shown to be strongly predictive of survival.…”