Separation of Lactic Acid Produced by Hydrothermal Conversion of Glycerol Using Ion-Exchange Chromatography

Abstract

Production of lactic acid by hydrothermal conversion of glycerol is an option to add value to the large amounts of glycerol that is being generated during the production of biodiesel. This work aimed to separate lactic acid by ion-exchange resins in a fixed-bed column. Adsorption isotherms were obtained from the breakthrough curves using different initial concentrations of lactic acid (60-302 g/l) and temperatures (30, 40 and 60 °C). Maximum adsorption capacities were estimated by the Langmuir model. Adsorption and desorption cycles for a binary and a real mixture were performed. The methodology proposed for the separation of lactic acid in a fixed-bed column presented high values of adsorptive capacity for both Amberlite IRA-96 and Amberlite IRA-67 resins at 30 °C. Lactic acid was more strongly adsorbed by Amberlite IRA-96 than the IRA-67 resin with maximum adsorption capacity of 544 and 341 g/l, respectively. Chromatographic experiments for the singlecomponent solution (lactic acid), binary mixture (lactic acid and glycerol) and real mixture showed high values of recovery (29.2%, 31.3% and 23.5%, respectively) and productivity (3.14, 7.00 and 2.43 kg of lactic acid/kg resin. day).

Productivity of a preparative high‐performance liquid chromatography isolation of anacardic acids from cashew nut shell liquid

“…The equations employed for solvent consumption and productivity calculations were adapted to the preparative HPLC system. Solvent consumption was calculated based on volumetric flow, run time, organic solvent percentage and mass of obtained products for each injection (equation ).…”

Glycerol valorization: conversion to lactic acid by heterogeneous catalysis and separation by ion exchange chromatography

“…More recently, Arcanjo et al . have evaluated the separation of lactic acid produced by hydrothermal conversion of glycerol using two ion exchange resins: Amberlite IRA 96 and IRA 67.…”

“…More recently, Arcanjo et al 85 have evaluated the separation of lactic acid produced by hydrothermal conversion of glycerol using two ion exchange resins: Amberlite IRA 96 and IRA 67. Amberlite IRA-96 (Q max = 544 g L −1 ) showed more adsorption capacity than on the IRA-67 resin (Q max = 341 g L −1 ).…”

“…Although the principles of separation of organic acids by ion exchange chromatography are well known, several studies report that there are still some details that need to be developed in particular systems. 78,[85][86][87][88][89][90] Such an effort seems to be justified because the technology based on ion exchange is a method that allows obtaining pure products in a single adsorption/desorption unit, making possible the integration of the product biosynthesis process with the separation and purification. 91 Another interesting study was carried out by Bishai et al 86 who investigated the lactic acid purification process from the fermentation broth, using a two-step process.…”

Silica and its Peculiarities

“…Tais interações podem ser controladas pela força iônica, eluente, pH, etc. 76,78 O carvão ativado é considerado um trocador iônico natural sendo esta propriedade enriquecida pela ativação química. A superfície de carvão tem tanto cargas negativas (aniônicas) como cargas positivas (catiônicas) para atrair íons livres em solução ou suspensão.…”