This research is focused on the utilization of cable waste originating during the recycling of wires as a partial substitution of natural aggregate in cement screed. The main goal of the work performed was to find an optimal level of substitution in terms of freezing–thawing resistance, which is a significant aspect for such type of concrete mixtures. The studied artificial aggregate was gradually dosed in cement screed by 5% in a volume of up to 30% of substitution. The influence of the substitution was also evaluated in terms of compressive strength, flexural strength, bulk density determination, and the ultrasonic pulse method. Gradual substitution led to the reduction of the bulk density and studied mechanical properties due to the considerable air-entraining effect. The utilization of cable waste reduced the value of modulus of elasticity and modified deformation behavior of studied mixtures, which exhibited significant softening during the flexural test. Studied screed mixtures incorporating waste material exhibited slightly lower values of the coefficient of freeze-thaw resistance in comparison with the control mixture, however, the attained values comply with technical requirements.