Separation of ¹⁹⁹Au(NCA) from Neutron Irradiated Platinum on Polythene

Abstract

Through adsorption on polythene, separation of 199 Au from neutron irradiated platinum has been studied. Distribution coefficients for Au and Pt have been obtained at various acid concentrations. The results have been used to develop a simple and rapid method for preparation of high specific activity 199 Au. The losses are ss10%.

Excitation functions of deuteron-induced nuclear reactions on natural platinum up to 24 MeV

“…It is important to mention that 199 Au can be readily produced as a NCA product in reactors via the indirect 198 Pt(n, c) 199 Pt ? 199 Au route followed by a complex separation procedure of 199 Au from the 198 Pt target [13]. On the other hand, charged particle irradiations on various targets can produce NCA 199 Au as well but with relatively lower amounts than the reactor production route [14,15].…”

Production of radio-gold 199Au for diagnostic and therapeutic applications

“…The relatively long half-life of 199 Au (T 1/2 = 3.139 d) provides a sufficient time for distribution, preparation and administration of radiolabeled drugs which then are cleared efficiently from the blood and non-target tissues [4] Pt target [5]. On the other hand, the production of 199 Au via charged particle irradiations on various targets shows NCA but relatively lower amounts than the reactor production route [6][7][8].…”

Production of carrier free192,193Hg and192,193Au in16O irradiated tantalum target and their separation by liquid-liquid extraction

“…[15][16][17] However, simultaneous production and separation of carrier-free isotopes of mercury and gold in charged particle activated target matrix have not been reported earlier. (T1/2=3.8 h) and 193mHg (7'1/2 = 11.8 h) have shorter half-lives compared to 2~ and 197Hg, which may be preferred from a view point of in vivo applications as the q-energies, intensities, etc., of these isotopes are favorable for medicinal applications.…”