Production of radio-gold 199Au for diagnostic and therapeutic applications

Abstract

Abstract. Production cross-sections of thenat Pt(d,x) 199 Au reactions have been measured from a 24-MeV deuteron energy down to the threshold by using a stacked-foil activation technique combined with HPGe -ray spectrometry. Only a partial agreement is obtained with the existing literature data. Theoretical data extracted from the TENDL-2013 library shows large discrepancy with the measured ones. Physical thick target yield for the 199 Au radionuclide was deduced using the measured cross-sections, and found a general agreement with the directly measured yield available in the literature. This study reveals that a low deuteron energy (<15 MeV) cyclotron and an enriched 198 Pt (100%) target could be used to obtain 199 Au in no carrier added form.