2002
DOI: 10.1128/jvi.76.3.1516-1520.2002
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Sequence and Genetic Arrangement of the USRegion of the Monkey B Virus (Cercopithecine Herpesvirus 1) Genome and Comparison with the USRegions of Other Primate Herpesviruses

Abstract: The sequence of the unique short (U S ) region of monkey B virus (BV) was determined. The 13 genes identified are arranged in the same order and orientation as in herpes simplex virus (HSV). These results demonstrate that the BV U S region is entirely colinear with that of HSV type 1 (HSV-1), HSV-2, and simian agent 8 virus.Cercopithecine herpesvirus 1 (monkey B virus [BV]) is a member of the alphaherpesvirus subfamily indigenous in Asiatic macaque monkeys. The natural history of BV in macaques is similar to t… Show more

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Cited by 27 publications
(20 citation statements)
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“…HVP2 has 98% homology with BV, as shown by genetic analysis [19]. Our results were in accord with this fact, and support the possibility of using HVP2 as an alternative antigen in BV diagnosis.…”
Section: Discussionsupporting
confidence: 88%
“…HVP2 has 98% homology with BV, as shown by genetic analysis [19]. Our results were in accord with this fact, and support the possibility of using HVP2 as an alternative antigen in BV diagnosis.…”
Section: Discussionsupporting
confidence: 88%
“…Squirrel monkeys are the natural host for this virus, 13 which is distantly related to the other primate herpesviruses (HHV-1, HHV-2, SA8, and B virus). 8,19 A definitive diagnosis can only be made by virus isolation and identification or by immunostaining techniques and molecular investigations as described in this study. Recently, the sequence of the glycoprotein B of squirrel monkey herpesvirus 1 was made public (accession number AYO95366, Breshears et al 2002).…”
Section: Pathologymentioning
confidence: 99%
“…In addition, herpes B virus shows strong serological cross-reactivity with HSV (5,18). The genetic arrangement is almost identical between herpes B virus and HSV (8,21,22,25), and the nucleotide sequences of the herpes B virus genes have been reported to show high homology with the corresponding HSV genes (1,21,22,25). These similarities suggest that a sample from a patient with herpes B virus infection also contains HSV and that misidentification occurs in a diagnosis of the infection.…”
mentioning
confidence: 67%