Sequence Comparison Between the Fusion Protein of Human and Bovine Espiratory Syncytial Viruses

Walravens, Karl; Kettmann, Richard; Collard, Alfred; Coppe, P.; Burny, Arsène

doi:10.1099/0022-1317-71-12-3009

Cited by 29 publications

(26 citation statements)

References 33 publications

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“…The results of the genetic studies indicate, in accordance with published data (Walravens et al, 1990 ;Lerch et al, 1991 ;Sullender et al, 1991), that the G gene region of BRSV is more variable than the F gene region. The observed divergences were located in a region corresponding to the extracellular domain and C-terminal parts of RSV strains (Cane et al, 1991).…”

Section: Discussionsupporting

confidence: 79%

Genetic and antigenic analysis of the G attachment protein of bovine respiratory syncytial virus strains.

Elvander

Vilček²,

Baule

et al. 1998

Journal of General Virology

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Antigenic and genetic studies of bovine respiratory syncytial virus (BRSV) were made on isolates obtained from three continents over 27 years. Antigenic variation between eight isolates was initially determined using protein G-specific monoclonal antibodies. Four distinct reaction patterns were observed, two of which corresponded to the previously established subgroups A and AB. A third pattern was produced by five Scandinavian strains and a fourth was observed from a single Dutch isolate. The genetic diversity of 27 strains of BRSV was investigated by comparative nucleotide sequence analysis of a 731 nucleotide fragment in the G protein gene. Nine of the BRSV strains were analysed by direct sequencing of RT-PCR amplicons whereas sequences of 18 BRSV and three human respiratory syncytial virus (HRSV) strains were ob-

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Section: Discussionsupporting

confidence: 79%

Genetic and antigenic analysis of the G attachment protein of bovine respiratory syncytial virus strains.

Elvander

Vilček²,

Baule

et al. 1998

Journal of General Virology

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“…Pairs of PCR primers used for amplification of the G gene of BRSV strains and size of PCR products obtained All primers were designed on the basis of the G sequence of strain RB94 ; the sequence of primer R3O1 was derived from strain BovX and that of primer D3 was derived from previously published G gene sequences (Lerch et al, 1990 ;. Primer F4 hybridizes to the F gene of strain RB94 (Walravens et al, 1990).…”

Section: Rt-pcrmentioning

confidence: 99%

“…A library of cDNA clones to the BRSV strain RB94 mRNA was constructed in the phage λgt11 (Walravens et al, 1990). Clones containing the G gene were identified by plaque hybridization using a $#P-labelled oligonucleotide (Eurogentec) made from the sequence of strain 391-2 (Lerch et al, 1990) …”

Section: Cloning Of a Complete Cdna Of The G Gene Of Strain Rb94mentioning

confidence: 99%

Antigenic and molecular analyses of the variability of bovine respiratory syncytial virus G glycoprotein.

Prozzi

Walravens²,

Langedijk³

et al. 1997

Journal of General Virology

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“…To delineate the genetic basis for the differences between HRSV and BRSV, we and others have undertaken cDNA cloning and nucleotide sequencing of BRSV genes for comparison with the sequences of the genes of HRSV. Recently, nucleotide sequences of the glycoprotein (G), fusion (F), nucleocapsid (N), matrix (M), small hydrophobic (SH) and M2 proteins of BRSV have been reported (Lerch et al, 1990;Walravens et al, 1990;Zamora & Samal, 1992a). There is 30%, 80%, 93%, 89%, 38% and…”

mentioning

confidence: 99%

Sequence comparison between the phosphoprotein mRNAs of human and bovine respiratory syncytial viruses identifies a divergent domain in the predicted protein

Mallipeddi

Samal

1992

Journal of General Virology

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The nucleotide and deduced amino acid sequences of the phosphoprotein (P) mRNA of bovine respiratory syncytial virus (BRSV) strain A51908 have been determined. The P mRNA is 860 nucleotides long with a single large open reading frame and the encoded polypeptide is 241 amino acids long. Comparison with the corresponding sequences of human respiratory syncytial virus (HRSV) subgroups A and B revealed 72 to 74% identity at the nucleotide level, and 81% at the amino acid level. The P protein contains a single divergent domain (37 % amino acid identity) flanked by highly conserved domains (87 % amino acid identity). The 3' end non-coding region is 47 nucleotides shorter than the corresponding region of HRSV. Comparison of the P mRNA sequences of two strains of BRSV (A51908 and FS-1) showed that there was extensive sequence identity at both the nucleotide (97%) and amino acid (97-9%) levels.

show abstract

Sequence Comparison Between the Fusion Protein of Human and Bovine Espiratory Syncytial Viruses

Cited by 29 publications

References 33 publications

Genetic and antigenic analysis of the G attachment protein of bovine respiratory syncytial virus strains.

Genetic and antigenic analysis of the G attachment protein of bovine respiratory syncytial virus strains.

Antigenic and molecular analyses of the variability of bovine respiratory syncytial virus G glycoprotein.

Sequence comparison between the phosphoprotein mRNAs of human and bovine respiratory syncytial viruses identifies a divergent domain in the predicted protein

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