“…Models that consider only a single unit neglect the possibility of admitting patients in a less appropriate care unit and thus the interaction between patient flows and the interrelationship between care units. Next to estimating utilization and the probability of admission rejections or delays, models that do incorporate multiple care units, also focus on the percentage of time that patients are placed in a care unit of a lower level or less appropriate care unit, or in a higher level care unit [11,108,202,217,327,439]. The first situation negatively impacts quality of care as it can lead to increased morbidity and mortality [478] and the second negatively impacts both quality of care, as it may block admission of another patient, and efficient resource use [217,439].…”