Sequential injection analysis (SIA)-chemiluminescence determination of indomethacin using tris[(2,2′-bipyridyl)]ruthenium(III) as reagent and its application to semisolid pharmaceutical dosage forms

Mervartová, Kateřina; Polášek, Miroslav; Calatayud, J. Martı́nez

doi:10.1016/j.aca.2007.01.057

Cited by 20 publications

(5 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…CVs recorded in the presence and absence of 1.0 × 10 −3 mol/L indomethacin at bare GCE, MnO 2 /GCE, Gr/GCE, and MnO 2 ‐Gr/GCE with PBS buffer of pH 7.0; scan rate: 100 mV/s.…”

Section: Resultsmentioning

confidence: 99%

“…Many analytical methods, such as spectrophotometry, fluorimetry, chemiluminescence (CL), micellar electrokinetic chromatography (MEKC), high performance liquid chromatography (HPLC), LC‐MS and enzyme‐linked immunosorbent assay (ELISA), are used to detect indomethacin. Although these methods successfully detect indomethacin in pharmaceutical and biological samples, some of them lack sensitivity and involve tedious procedure (time consuming or expensive).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Manganese dioxide‐graphene nanocomposite film modified electrode as a sensitive voltammetric sensor of indomethacin detection

Zhang

Huang

et al. 2016

Bulletin Korean Chem Soc

View full text Add to dashboard Cite

Excess amount of analgesic and anti‐inflammatory drug, such as indomethacin, often leads to serious gastrointestinal complications; therefore, amount of such active compound should be regulated in commercial drugs. This study proposes an efficient analytical technique to detect indomethacin selectively. We prepared and investigated electrochemical properties of a manganese dioxide‐graphene nanocomposite film modified glassy carbon electrode (MnO2‐Gr/GCE). The behavior of the modified electrode as electrocatalyst towards indomethacin oxidation was also examined. The cyclic voltammetric results reveal that the electrocatalytic activity for the oxidation of indomethacin can significantly be enhanced on the MnO2‐Gr/GCE. Indomethacin exhibited a sensitive anodic peak at about 0.90 V at MnO2‐Gr/GCE. The data obtained from differential pulse voltammetry showed that the anodic peak currents were linearly dependent on the indomethacin concentrations in the range of 1.0 × 10−7 to 2.5 × 10−5 mol/L with a detection limit of 3.2 × 10−8 mol/L (S/N = 3). Most importantly, the proposed method shows efficient and selective sensing of indomethacin in commercial pharmaceutical formulations. This is the first report of a voltammetric sensor for indomethacin using MnO2‐Gr/GCE. We believe that this new method can be commercialized for routine applications in laboratories.

show abstract

“…CVs recorded in the presence and absence of 1.0 × 10 −3 mol/L indomethacin at bare GCE, MnO 2 /GCE, Gr/GCE, and MnO 2 ‐Gr/GCE with PBS buffer of pH 7.0; scan rate: 100 mV/s.…”

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Manganese dioxide‐graphene nanocomposite film modified electrode as a sensitive voltammetric sensor of indomethacin detection

Zhang

Huang

et al. 2016

Bulletin Korean Chem Soc

View full text Add to dashboard Cite

show abstract

“…Pharmaceuticals containing nitrogen atoms in their chemical structures (mainly heterocyclic compounds and amines) feature a high potential of giving rise to an orange light emission while reacting with Ru(III) complexes, and hence can be detected by the Ru(III) complexes CL system. This trend can be exemplified by measurement of thiazides , indomethacin , meloxicam , promazine hydrochloride , piroxicam , quetiapine , penicillamine, ephedrine , chlorpheniramine and captopril and fluoroquinolones using the Ru(III) complexes CL system. However, there are some exceptions such as mandelic acid and vitamin A .…”

Section: Direct Methodsmentioning

confidence: 97%

Revisiting flow‐chemiluminescence techniques: pharmaceutical analysis

Iranifam

2012

Luminescence

View full text Add to dashboard Cite

The state of the art in flow-chemiluminescence (flow-CL) technique for automated pharmaceutical analysis is reviewed. Flow-CL approaches have become powerful and promising tools for pharmaceutical screening in recent years due to their simplicity, low cost and high sensitivity. Because of these advantages, these methods have been widely used for pharmaceutical analysis in recent years. The literature reviewed covers papers of analytical interest that appeared between 2007 and mid-2012 and have been divided into several sections based on fundamental types of CL systems employed. Furthermore, entries have been summarized alphabetically in tabular form giving details of analytical figures of merit of the methods.

show abstract

“…Indomethacin [1‐(p‐chlorobenzoyl)‐5‐methoxy‐2‐methyl‐3‐indolylacetic acid (Fig. 1)] is a non‐steroidal anti‐inflammatory drug, which represents antipyretic, analgesic and anti‐inflammatory effects [1, 2] and broadly used for the treatment of degenerative diseases of joints and ligaments such as rheumatoid arthritis, ankylosing spondylitis and osteoarthritis [3]. Oral administration of indomethacin may cause severe side effects and it is not the drug of first choice for minor aches and pain [4].…”

Section: Introductionmentioning

confidence: 99%

Surfactant coated magnetic nanoparticle‐based solid‐phase extraction coupled with spectrophotometric detection for determination of ultra‐trace amounts of indomethacin in biological fluids

Amoli‐Diva

Pourghazi²,

Pourasadollah-Karani

2015

Micro & Nano Letters

View full text Add to dashboard Cite

A novel mixed hemimicelle-based solid-phase extraction method using cetyltrimethylammonium bromide (CTAB) adsorbed onto the surface of magnetic Fe 3 O 4 nanoparticles was developed for extraction/preconcentration of ultra-trace amounts of indomethacin from biological fluids. Magnetic nanoparticles were synthesised via a simple chemical co-precipitation method and characterised by a transmission electron microscope, an X-ray diffractometer and Fourier transform infrared techniques. The method utilises the unique properties of Fe 3 O 4 nanoparticles including high surface area and superparamagnetism causing rapid separation (<20 min) and low adsorbent usage (only 50 mg). A comprehensive study on the parameters affecting the adsorption efficiency such as the amount of CTAB, pH of the solution, desorption conditions, amount of Fe 3 O 4 nanoparticles, extraction and preconcentration time, sample volume and ionic strength are presented. Under optimum conditions, the method's linearity was over a range of 25-450 ng ml −1. The limit of detection of 8.6 ng ml −1 , an enrichment factor of 99 and the relative standard deviation (%RSD) of 1.9% (for a concentration of 50 ng ml −1) were obtained. The method was successfully applied to determine indomethacin in human plasma and urine samples. Good recoveries (89-102%) with low % RSD, (1.7-2.7%) were achieved.

show abstract

Sequential injection analysis (SIA)-chemiluminescence determination of indomethacin using tris[(2,2′-bipyridyl)]ruthenium(III) as reagent and its application to semisolid pharmaceutical dosage forms

Cited by 20 publications

References 35 publications

Manganese dioxide‐graphene nanocomposite film modified electrode as a sensitive voltammetric sensor of indomethacin detection

Manganese dioxide‐graphene nanocomposite film modified electrode as a sensitive voltammetric sensor of indomethacin detection

Revisiting flow‐chemiluminescence techniques: pharmaceutical analysis

Surfactant coated magnetic nanoparticle‐based solid‐phase extraction coupled with spectrophotometric detection for determination of ultra‐trace amounts of indomethacin in biological fluids

Contact Info

Product

Resources

About