Sequential optimization and large scale production of lipase using tri-substrate mixture from Aspergillus niger MTCC 872 by solid state fermentation

Produção Microbiológica De Enzimas: Uma Revisão/Microbiological Production of Enzymes: A Review

“…A utilização de resíduos agroindustriais baratos como substrato na fermentação em estado sólido (FES) vem ganhando mais atenção devido à maior atividade em relação à fermentação submersa (FSm), no entanto, promover uma mistura desses substratos torna-se viável para o crescimento microbiano na FES. A mistura de substratos pode fornecer uma melhor área de superfície e acessibilidade da nutrição ao microrganismo (Mandari et al, 2020).…”

A review between whole-cells and immobilized lipases technologies for biodiesel and flavor esters production

“…Although solid-state fermentation has advantages such as benefit environmental sustainability, simplicity and low substrate cost, reduced water and energy demands, high productivity and produt concentration, some limitations make it difficult to scale up of this system. Examples of limitations include high media heterogeneity that reduces substrate accessibility, low efficiency in mass and heat transfer, and difficulty in controlling process parameters such pH, oxygen, humidity, temperature and cell growth (COLLA et al, 2016;GEOFFRY;ACHUR, 2018;GODOY et al, 2018;MANDARI et al, 2019). On the other hand, characteristics of the submerged fermentation, such as better nutrient distribution in the reactor, more rigorous monitoring of process variables and possibility of automation, make this process more efficient and productive and make it currently dominant in industrial production.…”

“…On the other hand, characteristics of the submerged fermentation, such as better nutrient distribution in the reactor, more rigorous monitoring of process variables and possibility of automation, make this process more efficient and productive and make it currently dominant in industrial production. However, a disadvantage is related to high cost of installation and maintenance of the equipment used to submerged fermentation (COLLA et al, 2016;FURINI et al, 2018;GEOFFRY;ACHUR, 2018;GODOY et al, 2018;MANDARI et al, 2019).…”

The effects of mannanase activity on viscosity in different gums

“…Nevertheless, Aspergillus sp. are also utilized in a widespread manner for the generation of microbial enzymes such as inulinase , 2020a, 2020bIlgın, Germec, & Turhan, 2020), phytase (Coban, Demirci, & Turhan, 2015a, 2015b, protease (Kalaskar, Kasinathan, Subrahmanyam, & Rao, 2020), lipase (Mandari, Nema, & Devarai, 2020), polygalacturonase (Karahalil et al, 2017), amylase (Pasin et al, 2020), cellulase (Dong et al, 2019), xylanase (de Souza et al, 2020 aside from β-mannanases (Duruksu, Ozturk, Biely, Bakir, & Ogel, 2009;Germec, Yatmaz, Karahalil, & Turhan, 2017;Karahalil, Germec, Karaoglan, et al, 2019;Karahalil, Germeç, & Turhan, 2019;Ozturk, Cekmecelioglu, & Ogel, 2010;Yatmaz, Germec, Karahalil, & Turhan, 2020;Yatmaz, Karahalil, Germec, Ilgin, & Turhan, 2016;Yatmaz, Karahalil, Germec, Oziyci, et al, 2016).…”