2018
DOI: 10.1080/10641955.2018.1524480
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Serial profile of flow-mediated dilatation in primigravida for prediction of preeclampsia and gestational hypertension

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Cited by 11 publications
(11 citation statements)
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“…28 On the contrary, there are publications reporting that there is a decrease with the gestational age. 29 Seeliger et al and Quinton et al reported that FMD increased from the first trimester to the second trimester in a normal pregnancy and reached its maximum in the middle of the second trimester. They stated that toward the end of pregnancy, FMD decreased significantly.…”
Section: Discussionmentioning
confidence: 95%
See 1 more Smart Citation
“…28 On the contrary, there are publications reporting that there is a decrease with the gestational age. 29 Seeliger et al and Quinton et al reported that FMD increased from the first trimester to the second trimester in a normal pregnancy and reached its maximum in the middle of the second trimester. They stated that toward the end of pregnancy, FMD decreased significantly.…”
Section: Discussionmentioning
confidence: 95%
“…Some studies also report that FMD increases in the first two trimesters and decreases in the last trimester 28 . On the contrary, there are publications reporting that there is a decrease with the gestational age 29 . Seeliger et al and Quinton et al reported that FMD increased from the first trimester to the second trimester in a normal pregnancy and reached its maximum in the middle of the second trimester.…”
Section: Discussionmentioning
confidence: 97%
“…20 Guimaraes DR et al, also reported a similar decrease in mean FMD in the third trimester in patients with GDM as compared to the controls (9.18%, 17.55% respectively). 21 When mean FMD was compared at 24-28 week POG, 36-38 weeks POG and 6-12 weeks post-partum in GDM patient and control group in our study it was found that the decrease in FMD at 36-38 weeks POG as compared to 24-28 weeks POG was statistically significant in both the groups (p<0.001), however this trend of change was similar in both the groups and was not statistically significant when compared between the two groups. In a recent study done by Malhotra AS et al serial assessment of endothelial function during pregnancy, using FMD for prediction of preeclampsia.…”
Section: Discussionmentioning
confidence: 99%
“…Similarly, another study reported that FMD significantly decreased from the 1st to 3rd trimester. FMD at the 3rd trimester effectively predicts the development of the condition with reported OR = 1.303; 95% CI 1.088-1.562; p = 0.004 with good diagnostic PLOS ONE accuracy [31]. Assessing maternal characteristics including BMI, MAP, Age, and Parity, biochemical and biophysical markers, fetal characteristics were reported in eight studies.…”
Section: Screening and Diagnosismentioning
confidence: 99%
“…FMD as an approach to predicting GH/PE was reported in two studies. Both reported FMD as an effective non-invasive approach [30,31], which is consistent with a recent review which reported that FMD is lower among women who later developed preeclampsia when compared to those without preeclampsia [59] and when taking �3.0% as a normal cut-off value for FMD in the brachial artery, the PPV for developing PE was 90%, and NPV was 100% which adds evidence to the assumption that women with impaired FMD in the brachial artery during early pregnancy are at risk for developing pre-eclampsia [60]. Maternal characteristics; age, parity, BMI, biochemical markers; serum PLGF, PAPP-A, βhCG, Doppler studies; MAP, Ut-PI, CRL, and foetal specific markers were also reported to be effective in predicting the development of hypertension/pre-eclampsia [32][33][34][35]37] Conversely, transvaginal colour Doppler assessment of the uterine arteries at 23 weeks of gestation reported a one-stage…”
Section: Gestational Hypertensionmentioning
confidence: 99%