Serial serum procalcitonin changes in the prognosis of acute stroke

Miyakis, Spiros; Georgakopoulos, Panagiotis; Kiagia, Maria; Papadopoulou, Olga; Pefanis, Aggelos; Gonis, A; Mountokalakis, T.

doi:10.1016/j.cccn.2004.08.002

Cited by 12 publications

(19 citation statements)

References 10 publications

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“…(4) Longterm follow-up was not done, so we are not able to correlate early serum PCT levels with mid-and long-term outcome. However, serum PCT levels in the acute stroke setting were reported not to be associated with outcome [21].…”

Section: Discussionmentioning

confidence: 98%

“…In patients with primary central nervous system (CNS) disorders (traumatic brain injury and spontaneous intracerebral hemorrhage), elevated admission serum PCT levels were reported to be useful in the prediction for VAP [20]. In acute stroke patients serum PCT levels were analyzed in only one study so far, ruling out a prognostic significance [21]. The diagnostic usefulness of serum PCT measurements in acute stroke patients for SARTI has not been analyzed systematically.…”

Section: Introductionmentioning

confidence: 97%

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Usefulness of Serum Procalcitonin Levels for the Early Diagnosis of Stroke-Associated Respiratory Tract Infections

et al. 2010

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Section: Discussionmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 97%

Usefulness of Serum Procalcitonin Levels for the Early Diagnosis of Stroke-Associated Respiratory Tract Infections

et al. 2010

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“…In another study, serum procalcitonin levels were evaluated in patients experiencing acute stroke, and an increase in serum procalcitonin levels was detected beginning from the 1st day, with the peak level reached on the 7th day. [22] In this study, procalcitonin levels were evaluated in AMI, which is an ischemic and acute inflammatory disease of the bowel. Carrying out the study on rabbits enabled repetitive blood to be drawn from the same subject, and thus the effect of ischemia duration on procalcitonin levels could be evaluated more accurately.…”

Section: Fig 4 Grade 4 Uulceration In Villus (H-e X 100)mentioning

confidence: 99%

Diagnostic and prognostic value of procalcitonin and phosphorus in acute mesenteric ischemia

Karabulut

Gül²,

Dündar³

et al. 2011

Ulus Travma Acil Cerrahi Derg

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AMAÇAkut mezenter iskemi (AMİ) modeli kullanılarak yapılan bu çalışmada, serum prokalsitonin ve fosfor düzeylerinin AMİ erken tanısında kullanılabilirliği araştırıldı. GEREÇ VE YÖNTEMÇalışmada 21 adet Yeni Zelanda tavşanı kullanıldı. Denekler Kontrol, Sham ve İskemi grubu olarak adlandırıl-dı. Kontrol grubundaki deneklere herhangi bir girişim yapılmadı. Sham ve İskemi grubundaki deneklere orta hat insizyonu ile laparotomi yapıldı. İskemi grubundaki deneklere ise laparatomi yapıldıktan sonra süperior mezenterik arter bulunarak bağlandı. Her üç gruptaki hayvanlardan 0., 1., 3. ve 6. saatlerde kan alındı, bu numunelerden prokalsitonin ve fosfor çalışıldı. BULGULARİskemi grubunda, serum fosfor ve prokalsitonin düzeyle-rindeki yükselme kontrol ve sham gruplarına göre istatistiksel olarak anlamlı bulundu (p<0,05). Fosfor ve prokalsitonin düzeylerinin, iskemi oluşturulduktan sonra 1. saatten itibaren arttığı ve bu yüksekliğin 6 saat boyunca devam ettiği saptandı (p<0,05). SONUÇFosfor ve prokalsitonin'in AMİ'nin erken tanısında ve prognozunda kullanılabilecek önemli parametreler olabileceğini düşünüyoruz.Anahtar Sözcükler: Akut mezenter iskemi; fosfor; prokalsitonin.

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“…Overall, the sensitivity and specificity of diagnosing PSI in the acute recovery period are currently unknown. New markers of bacterial sepsis (e.g., procalcitonin), some of which are available as bedside tests, may be more accurate in establishing a firm diagnosis of PSI [102][103][104]. In patients with head injury, a new qualitative IL-6 bedside test has been developed, and this test is claimed to be useful in predicting the risk of developing pneumonia [105].…”

Section: Diagnosing Post-stroke Infectionsmentioning

confidence: 99%

Systemic Infections After Acute Stroke

Kwan

Jenkinson²,

Vassallo³

et al. 2008

Aging Health

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After an acute stroke, systemic infection can complicate the recovery process and lead to a worse clinical outcome, including a higher risk of mortality. Post-stroke infection (PSI) is responsible for the majority of the mortality occurring between 1 week and 1 month after stroke, peaking towards the end of the second week. The effects of PSI on longer-term outcome and other aspects of recovery, such as cognition, mood and quality of life, are largely unknown. The cerebrovascular event itself may result in a systemic immunosuppressed state, hence lowering the threshold for subsequent systemic bacterial infections. Although there have been advances in the basic understanding of the pathophysiological mechanisms of PSI, clinical studies have not provided any clear guidelines on the best methods of managing or preventing PSI. This article provides a review of the current knowledge of the phenomenon of PSI and the possible future developments in the understanding and treatment of PSI.

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Serial serum procalcitonin changes in the prognosis of acute stroke

Cited by 12 publications

References 10 publications

Usefulness of Serum Procalcitonin Levels for the Early Diagnosis of Stroke-Associated Respiratory Tract Infections

Usefulness of Serum Procalcitonin Levels for the Early Diagnosis of Stroke-Associated Respiratory Tract Infections

Diagnostic and prognostic value of procalcitonin and phosphorus in acute mesenteric ischemia

Systemic Infections After Acute Stroke

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