Seroepidemiological Prevalence of Hepatitis Delta Virus in Eastern Saudi Arabia

Fathalla, Sami E.; Abdulazziz, Fatima Muhammad; Sabri, Hanny Saeed; Awad, Osman A.

doi:10.5144/0256-4947.1994.503

Cited by 13 publications

(14 citation statements)

References 17 publications

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“…The above studies and the present one indicate that pattern of endemicity of HAV infection is shifting in KSA (Tufenkeji, 2000). On contrary, seroprevalence study in Eastern region of KSA (Dammam) showed that hepatitis A virus infection starts dramatically high in school-age children, and then rise gradually with an increase in age reflecting high endemic of HAV in this region (Fathalla et al, 2000).…”

Section: Discussioncontrasting

confidence: 44%

Prevalence Study of Hepatitis A Virus (HAV) on Jeddah Population

Babaeer¹,

Awfi²

2011

Biosci., Biotechnol. Res. Asia

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Hepatitis A virus (HAV) infection is often a self limiting disease and infects millions of people worldwide every year. HAV infection is one of the most important public health problems all over the world, especially in areas with high prevalence rate of HAV. Seroprevalence of HAV infection shows great differences not only between different countries but also between different regions in the same country. It is inversely related to the level of socioeconomic status, sanitation and personal hygiene. The objective of this study was prevalence of Hepatitis A virus (HAV) on Jeddah population, Saudi Arabia. Also find out the relationship of our result with age, gender and ethnicity. Serum samples were collected from studied population between 2 and 35 or more years of age and stratified into the following age groups: 2 to 5, 6 to 9, 10 to14, 15 to19, 20 to 24, 25 to 29, 30 to 34 and more than 35 year, Serum samples were not available for less than 2 year of age. Serum samples also were stratified according to nationality into Saudi and non Saudi. And according to sex serum samples were stratified into male and female. Prevalence was calculated separately for each age group, for male and female separately, and for studied population as a whole. Sample sizes were calculated to achieve a 95% confidence interval (CI) of approximately ±5% for each age group. The determination of anti-HAV antibodies was carried out by ELISA-test.For all age groups, there was no significant difference between genders regarding anti-HAV seropositivity. The prevalence of IgG antibodies to HAV was 33.1% overall, 33.6% among males and 32.5% among females with no statistically significant difference (P>0.05). However, it increased significantly with the age. The IgG antibodies to HAV were found in 20.3 % of Saudi population, and 49% of non Saudi population (p<0.05). There was significant difference between nationality regarding anti-HAV seropositivity. The prevalence of HAV among adult population (39.3%) was higher than among children population (22.4%). The chi-square test showed significant differences in the prevalence of HAV between adult and children population (p<0.05).

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Section: Discussioncontrasting

confidence: 44%

Prevalence Study of Hepatitis A Virus (HAV) on Jeddah Population

Babaeer¹,

Awfi²

2011

Biosci., Biotechnol. Res. Asia

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“…This prevalence for HBsAg is lower than that reported in the eastern region (6.7%) and the southwestern region (5.4%), but higher than that reported from the central region (1.5%) of Saudi Arabia. 13,14 This prevalence is also higher than that reported from Western countries (0.1-0.5%), but lower than that from the Far Eastern countries. 15,16 The prevalence of HBsAg among blood donors has been found to be 3.8% in Syria, 9.8% in Yemen, 1.2% in Egypt, and 1.2-1.7% in India.…”

Section: Discussionmentioning

confidence: 60%

Prevalence of hepatitis B virus markers among blood donors in a tertiary hospital in Tabuk, northwestern Saudi Arabia

Beltagy

Balawi

Almuneef

et al. 2008

International Journal of Infectious Diseases

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The prevalence of HBV infection among male Saudi blood donors in the northwest region of Saudi Arabia is high compared to that reported from the central capital area (Riyadh). Public health education programs on HBV infection, adult hepatitis B immunization programs, and raising socioeconomic standards should be initiated in order to target the high-risk groups found in this study. Furthermore, a community-based study is recommended to investigate HBV infection in the northwest region of Saudi Arabia.

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“…This increase was due to resistance of enterovirus in the environment and the habits of the population studied. However, FATHALLA et al 5 and PAPAEVANGELOU et al 12 did not observed the seasonal variation in the prevalence of hepatitis A in Saudi Arabia and Greece, respectively. This study was carried out to investigate any seasonal variation in the occurrence of acute cases of hepatitis A in the city of Rio de Janeiro, Brazil.…”

Section: Introductionmentioning

confidence: 92%

Seasonal variation of hepatitis A virus infection in the city of Rio de Janeiro, Brazil

Villar

Paula

Gaspar

2002

Rev. Inst. Med. trop. S. Paulo

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Hepatitis A virus (HAV) infection constitutes a major public health problem in Brazil. The transmission of HAV is primarily by fecal-oral route so the water is an important vehicle of HAV dissemination. There is a great incidence of acute cases of hepatitis A in some areas of Brazil however the seasonal variation of these cases was not documented. The aim of this study was to determine the seasonality of HAV infection in Rio de Janeiro. From January 1999 to December 2001, 1731 blood samples were collected at the National Reference Center for Hepatitis Viruses in Brazil (NRCHV). These samples were tested by a commercial enzyme-immunoassay to detect anti-HAV IgM antibodies. Yearly positive rates were 33.74% in 1999, 32.19% in 2000, and 30.63% in 2001. A seasonal variation was recognized with the highest incidence in spring and summer. Furthermore a seasonal increase in incidence of HAV infection was found during the rainy season (December to March) because the index of rains is very high. It is concluded that HAV infections occur all year round with a peak during hot seasons with great number of rains.

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Seroepidemiological Prevalence of Hepatitis Delta Virus in Eastern Saudi Arabia

Cited by 13 publications

References 17 publications

Prevalence Study of Hepatitis A Virus (HAV) on Jeddah Population

Prevalence Study of Hepatitis A Virus (HAV) on Jeddah Population

Prevalence of hepatitis B virus markers among blood donors in a tertiary hospital in Tabuk, northwestern Saudi Arabia

Seasonal variation of hepatitis A virus infection in the city of Rio de Janeiro, Brazil

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