Serologic Evidence of Natural Togavirus Infections in Panamanian Sloths and Other Vertebrates *

Seymour, Charles; Peralta, Pauline H.; Montgomery, G. G.

doi:10.4269/ajtmh.1983.32.854

Cited by 35 publications

(44 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…7 This virus was first isolated in 1954 among five febrile patients from the island of Trinidad. 24 Casals and Whitman characterized MAYV as an arbovirus closely related to the Semliki Forest virus, 25 which was later confirmed by Lavergne et al 26 Circulating MAYV among humans, vertebrate reservoirs, and non-vertebrate vectors has been reported in Suriname, 25,27 Brazil, 28,29 Panama, 30 Trinidad and Tobago, 25 Bolivia, 6 Ecuador, 7 and Venezuela. 31 In addition, anti-MAYV antibodies have been reported among indigenous populations of Bolivia, Brazil, Colombia, Panama, Peru, Suriname, Trinidad and Tobago, Venezuela, French Guiana, and Mexico.…”

Section: History Of Mayaro Fever the Jungle Flumentioning

confidence: 71%

“…30 Another finding of that study was that yellow fever antibodies were also detected. 30 Among the 14 A. villosa primates, nine had antibodies against yellow fever virus. 30 Based on these findings, the authors concluded that in the Americas, sylvatic yellow fever was a monkey virus.…”

Section: Vertebrate Reservoirsmentioning

confidence: 78%

“…4,61 In Panama, agoutis (Dasyprocta punctata) and howler monkeys (Alouatta villosa) have been reported to have antibodies against MAYV. 30 The median positive titer was 1:128 (range 1:32 to 1:512). 30 Another finding of that study was that yellow fever antibodies were also detected.…”

Section: Vertebrate Reservoirsmentioning

confidence: 99%

“…30 The median positive titer was 1:128 (range 1:32 to 1:512). 30 Another finding of that study was that yellow fever antibodies were also detected. 30 Among the 14 A. villosa primates, nine had antibodies against yellow fever virus.…”

Section: Vertebrate Reservoirsmentioning

confidence: 99%

See 3 more Smart Citations

Mayaro virus: the jungle flu

Izurieta¹,

DeLacure²,

Izurieta³

et al. 2018

VAAT

View full text Add to dashboard Cite

Abstract:Mayaro fever is an emerging acute viral disease endemic in Central and South America. Mayaro virus (MAYV) is classified in the Semliki Forest virus antigenic complex and shares similarities with the alphavirus Chikungunya virus and the flavivirus Dengue virus. MAYV is an arbovirus transmitted by Haemagogus janthinomys, with competence also demonstrated in Aedes aegypti, Aedes scapularis, and Anopheles quadrimaculatus. Outbreaks and small epidemics of Mayaro fever have occurred in several countries in northern South America and the Caribbean. In addition, travel-associated cases have been reported in European nationals returning from endemic areas. Clinical features of Mayaro fever include fever, chills, persistent arthralgia, retro-orbital pain, maculopapular rash, itching, dizziness, and, rarely, lymphadenopathy. Methods of control for MAYV are similar to those used for other sylvatic arboviruses. Although MAYV was discovered as long ago as the 1950s and continues to be prevalent in the tropical areas of the Americas, it remains neglected and under-studied. This paper provides a thorough and current review of the published MAYV literature ranging from its original description to modern outbreaks, and from the basic virus characteristics to the clinical and epidemiological aspects of this disease.

show abstract

Section: History Of Mayaro Fever the Jungle Flumentioning

confidence: 71%

Section: Vertebrate Reservoirsmentioning

confidence: 78%

Section: Vertebrate Reservoirsmentioning

confidence: 99%

Section: Vertebrate Reservoirsmentioning

confidence: 99%

See 2 more Smart Citations

Mayaro virus: the jungle flu

Izurieta¹,

DeLacure²,

Izurieta³

et al. 2018

VAAT

View full text Add to dashboard Cite

show abstract

“…The main vector is the Haemagogus mosquito. Recent demographic changes in South America as well as the possibility of transmission and infection of humans via Aedes aegypti indicate increasing prevalence of this disease, considered as one of the major emerging diseases in the neotropics [9][10][11][12][13][14]. Macro domains (also called "X domains") are evolutionary conserved protein domains across a wide variety of species including viruses of the Coronaviridae and the Togaviridae families [15].…”

Section: Introductionmentioning

confidence: 99%

Preliminary insights into the non structural protein 3 macro domain of the Mayaro virus by powder diffraction

Papageorgiou¹,

Watier

Saunders

et al. 2010

Zeitschrift Für Kristallographie

View full text Add to dashboard Cite

Abstract. We present preliminary structural results of the non-structural protein 3 (nsP3) macro domain from the Mayaro virus (MAYV), an emerging virus of South American tropic regions, by means of synchrotron X-ray powder diffraction. Indexing of the diffraction patterns indicate a trigonal/hexagonal lattice (a ¼ 61:60 A, c ¼ 94:61 A), analogous to the known lattice of the sequence homologous nsP3 macro domain from the Chikungunia virus (CHIKV), though MAYV must have looser molecular packing: the cell dimensions of MAYV are significantly altered in comparison to CHIKV and the unit cell comprises 6 molecules and 58% solvent. The results are discussed in terms of their methodological and biological importance.

show abstract

Health evaluation of translocated free‐ranging primates in French Guiana

Thoisy

Vogel²,

Reynes

et al. 2001

American J Primatol

149

View full text Add to dashboard Cite

Among over 40 mammal species threatened by the filling of a hydroelectric dam reservoir in French Guiana, three species of primates have been translocated, comprising 124 red howler monkeys, six white-faced sakis, and 95 golden-handed tamarins. Health status of the animals was evaluated by direct physical examination and by hematological, biochemical, virological, and parasitological surveys of collected blood. The physical condition of the howlers was slightly worse toward the end of the capture period, but that of sakis and tamarins remained satisfactory. Several ectoparasites (ticks, larvae of dipterous insects, fleas, and lice) were collected, and various wounds, apparently nondebilitating, were recorded in howlers. Hematological and biochemical profiles determined for the three species revealed a slight anemia in howlers. Entamoeba, Strongyloides, and Trypanoxyurus were common in fecal samples of howlers. A survey of blood smears from the three species revealed infection by several types of microfilaria, Trypanosoma rangeli-like and Plasmodium brasilianum in all three, and Trypanosoma cruzi-like in howlers. These infections had no significant impact on the health status or the hematological profiles. Serologic investigations revealed occasional reactions against Toxoplasma gondii, a strong anti-Plasmodium response in the two Cebidae species, and a weaker one in tamarins. Attempts to isolate arbovirus failed, but antibody responses to Mayaro and yellow fever viruses were strong, especially in the howlers. A strong correlation between age and serological status led to a better understanding of the epidemic cycles. Our survey indicates French Guianan primates are reservoirs for several anthropozoonoses, including malaria, Chagas disease, and arboviruses.

show abstract

Serologic Evidence of Natural Togavirus Infections in Panamanian Sloths and Other Vertebrates *

Cited by 35 publications

References 0 publications

Mayaro virus: the jungle flu

Mayaro virus: the jungle flu

Preliminary insights into the non structural protein 3 macro domain of the Mayaro virus by powder diffraction

Health evaluation of translocated free‐ranging primates in French Guiana

Contact Info

Product

Resources

About