SEROLOGICAL AND MOLECULAR SURVEY OF Leptospira spp. AMONG CART HORSES FROM AN ENDEMIC AREA OF HUMAN LEPTOSPIROSIS IN CURITIBA, SOUTHERN BRAZIL

Finger, Mariane Angélica Pommerening; Filho, Ivan Roque de Barros; Leutenegger, Christian M.; Эстрада, Марко; Ullmann, Leila Sabrina; Langoni, Hélio; Kikuti, Mariana; Dornbush, Peterson Triches; Deconto, Ivan; Biondo, Alexander Welker

doi:10.1590/s0036-46652014000600003

Cited by 25 publications

(34 citation statements)

References 7 publications

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“…Leptospirosis is a wellknown ailment of horses, with significant clinical and reproductive repercussions (Tadich et al 2016). Our study shows that draft horses in urban settings are particularly exposed to the disease, with a seroprevalence of 28.57%, compared to other populations of the same region (Finger et al 2014). To our knowledge, this is the first study in Brazil to focus on this population.…”

Section: Discussionmentioning

confidence: 63%

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Prevalence and Risk Factors Associated With Equine Leptospirosis in an Endemic Urban Area in Southern Brazil

Dewes

Fortes

Machado

et al. 2020

BJD

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The burden of equine leptospirosis in Pelotas (RS) remains unclear due to underreporting. In this city, socially vulnerable families use these animals to collect food and recyclable material. In this context, this study aimed to know the seroprevalence of leptospirosis in urban working horse population in Pelotas, and to assess risk factors for equine leptospirosis in the study area. Serum samples from 119 horses were analysed by microscopic agglutination test (MAT). As results, 28.57% (n=34) animals were positive in the MAT with titres equal or above 400. Canicola was the most prevalent serovar in this study, followed by Hardjo, Bratislava, and Ballum. Exposure to risk factors was assessed and the occurrence of abortions (p = 0.04) and the occurrence of stillborn foals in the establishments (p = 0.04) were associated with the disease. Furthermore, abortion itself was associated with factors usually regarded as having leptospirosis risk, these were: Grazing on open pastures (p<0.01); the presence of rodents in or around the house (p<0.01); and forage being kept in sheds (p=0.03). Conversely, fodder stored in plastic barrels (with lids) seems to reduce the risk of abortion (p=0.01). Thus, urban working horses used to collect food and recyclable materials in different parts of the city may be potential spreaders of the disease to humans and other animal species. In addition, our study indicates that these animals may be viable sentinels in the research of circulating serovars in urban settings.

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Section: Discussionmentioning

confidence: 63%

“…In southernmost Brazil, equine leptospirosis varies greatly. Studies that considered draft horses in urban settings show prevalences of 60% and 75% (Finger et al 2014;Lasta et al 2013).…”

Section: Introductionmentioning

confidence: 99%

Prevalence and Risk Factors Associated With Equine Leptospirosis in an Endemic Urban Area in Southern Brazil

Dewes

Fortes

Machado

et al. 2020

BJD

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“…An even higher prevalence of antibodies against Leptospira spp. was observed in cart horses (75.8%), also with Icterohaemorrhagiae as the most frequent serogroup (80.8%) (Finger et al 2014). In this area, poor sanitary conditions and infrastructure, proximity to garbage dump sites and open sewers and flooding were associated to seroprevalence of leptospirosis (Bier et al 2012, Finger et al 2014).…”

Section: Discussionmentioning

confidence: 99%

“…was observed in cart horses (75.8%), also with Icterohaemorrhagiae as the most frequent serogroup (80.8%) (Finger et al 2014). In this area, poor sanitary conditions and infrastructure, proximity to garbage dump sites and open sewers and flooding were associated to seroprevalence of leptospirosis (Bier et al 2012, Finger et al 2014). Since Vila Pantanal and Curitiba zoo are both located in Iguaçu Municipal Park and Iguaçu River go through them, it may be considered that animals from both places are submitted to the same environmental conditions and risk factors.…”

Section: Discussionmentioning

confidence: 99%

Serological survey of anti-Leptospira spp. antibodies in Barbary sheep (Ammotragus lervia) at the Curitiba Zoo, southern Brazil

et al. 2018

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Leptospirosis is a worldwide zoonosis, affecting humans, domestic and wild animals. The present study aimed to evaluate prevalence of anti-Leptospira spp. antibodies in Barbary sheep at the Curitiba zoo. Microscopic agglutination test (MAT) was performed using 17 serogroups. Antibodies against Leptospira spp. were observed in 23.5% samples and Icterohaemorrhagiae was the only prevalent serogroup. The presence of anti-Leptospira antibodies in Barbary sheep indicates exposure to leptospires; thus monitoring and preventive measures are necessary in zoo’s captive animals, since they can act as sentinels of environmental exposure in an area with high movement of people.

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“…To overcome all these limitations polymerase chain reaction (PCR) have been used, which is considered sensitive and specific for the rapid detection of Leptospira in clinical samples. Evaluation of PCR-based studies for the identification and diagnosis of leptospirosis has been reported elsewhere, in humans and animals [13,28,29,30]. It has been developed for the rapid detection of Leptospira DNA and has the potential to make a dramatic impact in diagnosing leptospirosis [25].…”

Section: Polymerase Chain Reaction (Pcr)mentioning

confidence: 99%

A Review of Laboratory Diagnosis and Treatment of Leptospirosis

Al-orry¹,

Arahou²,

Hassikou³

et al. 2016

Int J Pharm Pharm Sci

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Leptospirosis is an infectious disease affect human and animal. The diagnosis is challenging due to none specific clinical features, lack of awareness and poor access to health care. Therefore the disease becomes underreported. Early diagnosis is essential because antibiotic treatment is most effective when it is initiated early. However, laboratories tests for early diagnosis still lacking. The disease may be demonstrated by direct or indirect methods. Direct methods are the detection of the organism or its components and indirect methods are the detection of specific antibodies of the organism. This review highlights the major diagnostic techniques in leptospirosis with their advantages and disadvantages as well as the treatment. The search criteria focused on the thesis we obtained and searching in the websites (Google

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SEROLOGICAL AND MOLECULAR SURVEY OF Leptospira spp. AMONG CART HORSES FROM AN ENDEMIC AREA OF HUMAN LEPTOSPIROSIS IN CURITIBA, SOUTHERN BRAZIL

Cited by 25 publications

References 7 publications

Prevalence and Risk Factors Associated With Equine Leptospirosis in an Endemic Urban Area in Southern Brazil

Prevalence and Risk Factors Associated With Equine Leptospirosis in an Endemic Urban Area in Southern Brazil

Serological survey of anti-Leptospira spp. antibodies in Barbary sheep (Ammotragus lervia) at the Curitiba Zoo, southern Brazil

A Review of Laboratory Diagnosis and Treatment of Leptospirosis

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