Serological detection of Cytomegalovirus in blood samples from infected women in Misan province, Iraq

Abstract

Cytomegalovirus is a species of Herpesviridae can that infect humans and cause latent and severe infections. Severe human infection caused by Human Cytomegalovirus (HCMV) usually occurs in humans who suffer from immunodeficiency. This research aims to detect antibodies IgM as a primary infection and IgG as a secondary infection in women suffering from repeated abortion and determines the more ages susceptible to HCMV infection. Blood sera were taken from females of different ages, from 15-45 years, based on clinical manifestation and abortion. The sample sizes in this study were taken from 150 patients, of which 100 cases were positive for HCMV. We recorded a high percentage of CMV infection (25%) and a high abortion rate (27.5%) in patients at age 20-24 years with a high rate of IgG, and we noticed a low rate of CMV infection (10%) in the age group 35-39 years with a low rate of IgG, we also reported a high abortion rate (27.27%) related with present IgM. The percentage of abortion was (26.66%) reported in patients ages 15-19 and 40-45 years, with (a 33.33%) rate of IgM and IgG. Keywords: Human Cytomegalovirus HCMV; abortion; IgM; IgG.