Serological evidence of natural exposure of camels Camelus dromedaries to foot and mouth disease virus

Yousef, M. R.; Mazloum, K. S.; Al-Nakhli, Habeeb M.

doi:10.5455/vetworld.2012.197-200

Cited by 7 publications

(12 citation statements)

References 2 publications

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“…The Camelidae are found in countries like North and East Africa, Middle and East Asia as well as South America where FMD is endemic (Du et al, 2009 (Yousef et al, 2012). The two closely related camel species of Bactrian and dromedary camels possess noticeably different susceptibility to FMD virus (Larska et al, 2009).…”

Section: Introductionmentioning

confidence: 99%

“…Bactrian camels under experimental studies can easily develop obvious clinical sign of FMD (Larska et al, 2009), while several investigation appear to suggest that dromedaries are less susceptible to inoculation with FMD virus serotype O but that they do not present a risk in transmitting the disease to susceptible animals (Wernery and Kaaden, 2004;Alexandersen et al, 2008). However, Kumar et al (1983) have described the isolation of FMDV serotype O from one of two randomly selected dromedaries in India, and Moussa et al (1987) in Egypt described a strain of type O FMD virus isolated in Giza from a camel with vesicular, ulcerative stomatitis and they suggested that dromedaries are susceptible to natural FMD infection (Yousef et al, 2012).…”

Section: Introductionmentioning

confidence: 99%

“…Four (A, O, SAT 1 and 2) out of this seven serotype exist in Nigeria (unpublished data). Footmouth-disease virus (FMDV) is a small non-enveloped virus and has a genome of 8.5 kb which encodes for structural as well as non-structural proteins (NSPs) (Yousef et al, 2012). The viral capsid composed of four structural proteins, VP1, VP2, VP3 and VP4 (Fry et al, 2005).…”

Section: Introductionmentioning

confidence: 99%

“…A structural protein produces antibodies to FMDV in vaccinated animals, whereas infected animals produce antibodies to both the structural and non-structural proteins (Yousef et al, 2012). Meanwhile, assays to demonstrate antibodies against non-structural proteins have potential to differentiate infected animals from vaccinated (Berger et al, 1990;Rodriguez et al, 1994;De Diego et al, 1997;Clavijo et al, 2004).…”

Section: Introductionmentioning

confidence: 99%

“…Furthermore, camels are frequently moved across the desert of Niger, Chad, Benin and Central African Republic to Nigeria across areas that FMD outbreak is endemic in cattle and other small ruminants. Therefore, it is possible that camels may play a possible role in the maintenance and transmission of FMDV and may carry FMDV over a very long distance and across the borders (Yousef et al, 2012). However, because of the limited information concerning FMDV in camels in West Africa, Nigeria in particular, this study was aimed to investigate the serological evidence of natural exposure of camels (Camelus dromedaries) to FMD virus.…”

Section: Introductionmentioning

confidence: 99%

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Serological evidence of foot-and-mouth disease virus (FMDV) in camels (Camelus dromedaries) in Nigeria

Ularamu¹,

Wungak²,

Lazarus³

et al. 2015

J. Vet. Med. Anim. Health

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Serological evidence of foot-and-mouth disease virus (FMDV) in camels (Camelus dromedaries) in Nigeria

Ularamu¹,

Wungak²,

Lazarus³

et al. 2015

J. Vet. Med. Anim. Health

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Foot-and-mouth disease virus O/ME-SA/Ind 2001 lineage outbreak in vaccinated Holstein Friesian cattle in Saudi Arabia in 2016

Hemida

EL-Ghareeb

Al-Hizab

et al. 2018

Veterinary Quarterly

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Background: Foot-and-mouth disease virus (FMDV) is a highly contagious viral infection of large ruminants. Despite the massive application of vaccines against FMDV, several outbreaks are still being reported in Africa and Asia.Aim: To perform molecular characterization of FMDV in an outbreak among a cattle herd Saudi Arabia in 2016. This herd had been vaccinated with a polyvalent FMDV vaccine.Methods: To investigate this outbreak, we collected specimens from 77 animals showing typical clinical signs of FMDV. Specimens including sera, nasal swabs, and tissues (tongue, coronary bands, hooves, and hearts) were collected. We tested the collected cattle sera for the presence of FMDV antibodies with commercial ELISA kits. In addition, we tested the swabs for the presence of the most common FMDV strains (O, A, Asia-1 and SAT-2) with RT-PCR using serotype-specific oligonucleotides.Results: Serology showed that 22% of the tested sera were positive. Molecular testing of the examined swabs confirmed that 24% of the tested animals were positive. Our sequencing analysis confirmed that the circulating strains of FMDV belonged to FMDV serotype O. The phylogenetic tree based on the FMDV-VP-1 gene revealed high nucleotide identity between the circulating strains and the Bangladesh strain (99%). These strains were distinct (shared 89% nucleotide identity) from the FMDV-O strains used for the preparation of the vaccine administered to the animals in this herd. Moreover, they had 7% nucleotide difference between the FMDV-O strains reported in Saudi Arabian in 2013.Conclusion: More in-depth molecular characterization of these FMDV strains is warranted.

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Seroprevalence of Foot and Mouth Disease Virus Infection in some Wildlife and Cattle in Bauchi State, Nigeria

Atuman

Kudi

Abdu

et al. 2019

Preprint

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18Background 19 Foot and mouth disease (FMD) is one of the most economically important transboundary 20 animal diseases with devastating consequence on livestock production and wildlife 21 conservation. The objectives of the study were: to determine the seroprevalence of FMDV in 22 wildlife and cattle and identify circulating FMDV serotypes in wildlife and identify potential 23 risk factors that will contribute to transmission of the disease at the wildlife-livestock 24 interface in Yankari Game Reserve and Sumu Wildlife Park in Bauchi State, Nigeria. 25 Methods 26Blood samples were collected between 2013 to 2015 from some wildlife and cattle 27 respectively within and around Yankari Game Reserve (YGR) and Sumu Wildlife Park 28 (SWP) in Bauchi State, Nigeria. The Wild animals were immobilized for blood collection 29 using a combination of Etorphine Hydrochloride (M99® Krüger-Med South Africa ) at 0.5-2 30 mg/kg and Azaperone (Stresnil®, Janssen Pharmaceuticals (Pty.) Ltd., South Africa) at 0.1 31 mg/kg using a Dan-Inject® rifle (Dan-Inject APS, Sellerup Skovvej, Denmark) fitted with 3 32 ml dart syringe and for reversal, Naltrexone (Trexonil® Kruger-Med South Africa) at 1.5 mg 33 IM was used, cattle were restrained by the owners for blood collection. Harvested Sera from 34 blood were screened for presence of Antibodies against FMDV using prioCHECK® 3 ABC 35 NSP ELISA kit and positive samples from wildlife were serotyped using Solid-Phase 36Competitive ELISA, (IZSLER Brescia-Italy). Data obtained were analysed using Graphpad 37 Prism version 7. 38 Results 39The results showed that 197 (65.7%) of the 300 serum samples from cattle and 13 (24.5%) of 40 the 53 serum samples from wildlife tested positive for antibodies to the highly conserved 2 41 non-structural 3-ABC protein of FMDV and statistically significant (P <0.05). Classification 42 of cattle into breed and sex showed that detectable antibodies to FMDV were higher (P 43 <0.05) in White Fulani 157 (72.8%) than red Bororo 23 (39.7%) and Sokoto Gudali 17 44 (33.3%) breeds of cattle whereas in females detectable FMDV antibodies were higher (P 45 <0.05) 150 (72.8%) than in males 47 (50.0%). In the wildlife species, antibodies to FMDV 46 were detected in waterbuck 2 (28.6%), elephant 1 (25.0%), wildebeest 4 (33.3%) and eland 6 47 (25.0%). Four serotypes of FMDV: O, A, SAT-1 and SAT-2 were detected from the 3-ABC 48 positive reactors in waterbuck, elephant, wildebeest and eland. Contact of wildlife and cattle 49 during utilization of the rich resources in the conservation areas is a potential risk factor for 50 the spread of FMDV in the study area. 51 Conclusions 52 Presence of FMDV antibodies in cattle and some wildlife were observed and serotypes of 53 FMDV: O, A, SAT-1 and SAT-2 were detected from the 3-ABC positive reactors in some of 54 the wildlife. The study highlights the need for active surveillance of FMDV in wildlife and 55 pastoral cattle within and around wildlife conservation areas in Nigeria. FMD surveillance 56 system, control and prevention progra...

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Serological evidence of natural exposure of camels Camelus dromedaries to foot and mouth disease virus

Cited by 7 publications

References 2 publications

Serological evidence of foot-and-mouth disease virus (FMDV) in camels (Camelus dromedaries) in Nigeria

Serological evidence of foot-and-mouth disease virus (FMDV) in camels (Camelus dromedaries) in Nigeria

Foot-and-mouth disease virus O/ME-SA/Ind 2001 lineage outbreak in vaccinated Holstein Friesian cattle in Saudi Arabia in 2016

Seroprevalence of Foot and Mouth Disease Virus Infection in some Wildlife and Cattle in Bauchi State, Nigeria

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