2019
DOI: 10.1007/s00436-019-06373-z
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Serological survey and risk factors of Aelurostrongylus abstrusus infection among owned cats in Italy

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Cited by 15 publications
(16 citation statements)
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“…When utilizing a horseradish peroxidase (HRP)-conjugated secondary antibody, sensitivity ranged from 88.2% to 100% and specificity from 85% to 92.6%, depending on the used plate type [ 28 ]. Until now, the ELISA has mainly been used in epizootiological research studies but is not commercially available for clinical diagnosis, although it is offered and performed in specialised labs [ 30 , 31 , 32 , 33 ]. It should be taken into account that based on the nature of the diagnostic antigen, seroconversion is dependent on the presence of adult male lungworms.…”
Section: Introductionmentioning
confidence: 99%
“…When utilizing a horseradish peroxidase (HRP)-conjugated secondary antibody, sensitivity ranged from 88.2% to 100% and specificity from 85% to 92.6%, depending on the used plate type [ 28 ]. Until now, the ELISA has mainly been used in epizootiological research studies but is not commercially available for clinical diagnosis, although it is offered and performed in specialised labs [ 30 , 31 , 32 , 33 ]. It should be taken into account that based on the nature of the diagnostic antigen, seroconversion is dependent on the presence of adult male lungworms.…”
Section: Introductionmentioning
confidence: 99%
“…Christmas Island 25.0% [24]). A supposed risk factor for A. abstrusus infection is young age [5,13,19,23,25], potentially due to an immature immune system [23,26]. Other factors that have been linked to a higher prevalence are neutering status [5,13], FIV infection [25] and outdoor access [5,10,13].…”
Section: Introductionmentioning
confidence: 99%
“…An ELISA for the detection of serum antibodies against A. abstrusus using recombinantly expressed bovine lungworm major sperm protein (MSP) as diagnostic antigen [28] has been recently developed [26]. However, this serological test is being used only in experimental and epizootiological studies so far [13,18,20,25].…”
Section: Introductionmentioning
confidence: 99%
“…They all belong to the same taxonomic family, have a comparable life cycle, and may result in serological cross-reactions when testing for anti-A. abstrusus antibodies [17,21]. Capillaria spp.…”
Section: Discussionmentioning
confidence: 99%