Serological survey for antibodies against pestiviruses in Wyoming domestic sheep

Silveira, Simone; Falkenberg, Shollie M.; Elderbrook, Molly J; Sondgeroth, Kerry S.; Dassanayake, Rohana P.; Neill, John D.; Ridpath, Julia F.; Canal, Cláudio Wageck

doi:10.1016/j.vetmic.2018.04.019

Cited by 10 publications

(8 citation statements)

References 20 publications

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“…Each species has multiple subgenomes: BVDV-1 can be divided into at least 21 subgenomes (1a-1u) and BVDV-2 can be divided into four subgenomes (2a-2d) (8). BVDV-1, BVDV-2, Border disease virus (BDV), and HoBi-like viruses have been identified from sheep and cattle (9). Cattle, sheep, and goats are the main domestic livestock across the world, and widespread infection with BVDV disease has caused huge economic losses to the livestock industry (10), with the cross-infection of a variety of animals making prevention and control of the disease difficult (11).…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Bovine Viral Diarrhea Virus in Ovine and Caprine Flocks: A Global Systematic Review and Meta-Analysis

et al. 2021

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Background: Bovine viral diarrhea virus (BVDV) is the causative agent of bovine viral diarrhea. It can infect cattle, sheep, pigs, and other animals, causing diarrhea, miscarriage, and stillbirth, among other symptoms, and it can result in huge economic losses to animal husbandry. There are reports on BVDV infection rates in sheep and goat herds from all over the world and this meta-analysis aimed to evaluate the prevalence of and risk factors for BVDV in sheep and goats.Results: Using the data of 41,297 sheep and goats in 24 countries/regions to calculate a comprehensive prevalence rate for BVDV. The overall prevalence of BVDV infection in sheep and goats was estimated to be 8.6% (95% CI: 5.2–12.7) by immunological methods and 7.3% (95% CI: 2.7–13.7) by molecular methods. Analysis by national income level revealed that prevalence is higher in middle-income countries than in high-income countries (P < 0.05). The study also compared prevalence rates by species of BVDV, sampling year, and test species, but did not find significant differences.Conclusion: This systematic review and meta-analysis is the first to determine the global prevalence of BVDV in ovine and caprine flocks. The prevalence of BVDV in sheep and goat populations varies from region to region, and the situation is not optimistic in some countries.

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Section: Introductionmentioning

confidence: 99%

Prevalence of Bovine Viral Diarrhea Virus in Ovine and Caprine Flocks: A Global Systematic Review and Meta-Analysis

et al. 2021

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“…To date, at least 23 genotypes of Pestivirus A (12)(13)(14)(15)(16) and six genotypes (17) of Pestivirus B have been classified based on sequence comparison analyses and the palindromic nucleotide substitutions (PNS) genotyping method (18,19). Pestivirus H, first isolated from fetal calf serum (20), has spread to different continents, including North America, South America, Europe, and Asia (21)(22)(23)(24)(25)(26). In China, nine genotypes of Pestivirus A (1a,1b, 1c,1d, 1m, 1o, 1p,1q, and 1u) (27)(28)(29)(30), two genotypes (2a, 2b) of Pestivirus B (31)(32)(33), and Pestivirus H (24,34) have been reported.…”

Section: Introductionmentioning

confidence: 99%

Genetic Diversity of Bovine Pestiviruses Detected in Backyard Cattle Farms Between 2014 and 2019 in Henan Province, China

Shi

Zhang

et al. 2020

Front. Vet. Sci.

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Bovine pestiviruses include Pestivirus A (BVDV-1), Pestivirus B (BVDV-2), and Pestivirus H, which was originally called HoBi-like pestivirus. We conducted an epidemiological investigation for pestiviruses circulating in backyard cattle farms in central China. RT-PCR assays and sequences analysis were conducted on 54 nasal swabs, 26 serum samples, and three lung samples from cattle with respiratory infections and identified 29 pestivirus strains, including 24 Pestivirus A and five Pestivirus H strains. Phylogenetic analysis based on partial 5 ′-UTR and Npro sequences showed that the genotypes of 24 Pestivirus A strains included Pestivirus A 1b (six isolates), Pestivirus A 1m (six isolates), Pestivirus A 1q (two isolates), Pestivirus A 1u (one isolates), and Pestivirus A 1o (nine isolates, a putative new sub-genotype). In addition, a single Pestivirus H agenotype included all five Pestivirus H strains. This study revealed extensive genetic variations within bovine pestivirus isolates derived from cattle in backyard farms in Central China, and this epidemiological information improves our understanding of the epidemics of bovine Pestiviruses, as well as will be useful in designing and evaluating diagnostic methods and developing more effective vaccines.

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“…To determine the comparative strength of neutralization we adopted the formula established by Silveira et al ( 34 ). Within the positive samples, 41.4% did not have a predominant titer against one specific subtype of BVDV.…”

Section: Resultsmentioning

confidence: 99%

“…To compare the predominance of titers against the different BVDV subtypes, a formula established by Silveira et al ( 34 ) was used for determining the comparative ratio (R) for each serum sample: R subtypeA = (4 × titer against subtype A)/(titer against subtype B + titer against subtype C + titer against subtype D). If the value for one subtype was >0.231 than the value for the other subtype, the sample was considered to have predominant titer for the respective subtype.…”

Section: Methodsmentioning

confidence: 99%

Vaccination Failure in Eradication and Control Programs for Bovine Viral Diarrhea Infection

et al. 2021

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Vaccination against bovine viral diarrhea (BVD) is one of the key elements to protect cattle herds from this economically important disorder. Bovine viral diarrhea virus (BVDV) is a pestivirus infecting animals at all ages with significant impact on reproductive, digestive, and respiratory systems. Financial burden caused by this pathogen prompts many farmers to introduce vaccination as the control and prophylactic measure especially when persistently infected (PI) individuals, being the main source of the virus in the herd, are removed after test-and-cull approach. The aim of the study was to compare the serological response in cattle herds where new PI calves were identified without prior removal of PI animals or despite their removal and after the introduction of whole herd vaccination against BVDV infection. Overall seroprevalence in 5 vaccinated herds was 91.7 and 83.3% using ELISA and virus neutralization test, respectively. Despite high titers for both vaccine and field strains of BVDV in analyzed herds the analysis of comparative strength of neutralization indicated that 41.4% of positive samples did not have a predominant titer against one specific subtype of BVDV. In 3 herds BVDV-1b subtype was identified while in 2 others it was BVDV-1d, while the vaccine used was based on BVDV-1a which was never identified in Poland so far. To increase the success of the BVDV eradication program, a careful approach is suggested when planning herd vaccination. Comparison of existing field strains and their similarity with vaccine strains at antigenic and genetic levels can be a useful approach to increase the effectiveness of vaccination and efficient protection of fetuses from persistent infection.

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Serological survey for antibodies against pestiviruses in Wyoming domestic sheep

Cited by 10 publications

References 20 publications

Prevalence of Bovine Viral Diarrhea Virus in Ovine and Caprine Flocks: A Global Systematic Review and Meta-Analysis

Prevalence of Bovine Viral Diarrhea Virus in Ovine and Caprine Flocks: A Global Systematic Review and Meta-Analysis

Genetic Diversity of Bovine Pestiviruses Detected in Backyard Cattle Farms Between 2014 and 2019 in Henan Province, China

Vaccination Failure in Eradication and Control Programs for Bovine Viral Diarrhea Infection

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