Seroprevalence Hepatitis B in Blood Donors at Lubumbashi, DR Congo (Case of Provincial Hospital Sendwe Reference)

Michel, Kabamba Nzaji; Pascal, Kabwe Matanda; Mariette, Kaki Khang; Blaise, Ilunga Kahaki; Tonny, Nkongal Nkongal; Ignace, Bwana Kangulu; Elie, Kilolo Ngoy Umba; Ilunga, Kabyla Benjamin; Oscar, Luboya Numbi

doi:10.4236/oalib.1103105

Cited by 3 publications

(8 citation statements)

References 7 publications

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“…The difference observed is not statistically significant (p > 0.05). This was mentioned by Michel [6] in the DRC. Similarly, the prevalence of HBSAg in blood donors aged 18 to 38 (4.2%) and 39 to 58 years (2.7%) was not statistically significant (p > 0.05).…”

Section: /15mentioning

confidence: 99%

“…Family donors were the only ones affected by HBV in our series and the difference observed was significant (p < 0.05) [6]. It is here that the need for NBTP to organize public awareness campaigns in favor of regular voluntary blood donations in order to achieve the WHO 2020 targets: 100% voluntary donations [52].…”

Section: /15mentioning

confidence: 99%

“…In the Democratic Republic of Congo, this seroprevalence is lower than Kakisingi [25] 8.01% and Michel [6] 6.8% in Lubumbashi, Batina in Kisangani 6.0% [7], Mbendi in Kinshasa 9.2% [24]; greater than 1.6% obtained by Kabamba Nzaji [28] in rural Kamina; and close to 3.7% of Namululi [27] and Kabinda [33] 4.2% of volunteer donors in Bukavu. Infectious risk in blood recipients appears to be certain in all provinces of the DRC and viral hepatitis B continues to be the reason for exclusion from donating blood.…”

Section: The Seroprevalence Of Hbv Infection In Blood Donorsmentioning

confidence: 99%

“…In the Democratic Republic of Congo, the seroprevalence of hepatitis B virus infection among blood donors is 1.6% to 9.2%: Kinshasa 9.2% [24], Lubumbashi 8.0% [25] and 6.8% [6], Kisangani 6.0% [26], Bukavu 3.7% [27] and 1.6% in rural areas of Kamina [28]. In Moba, there are no studies evaluating the seroprevalence of hepatitis B (carriage of HBS antigen) among blood donors.…”

Section: Viral Hepatitis B (Hvb) Is An Inflammation Of the Liver Withmentioning

confidence: 99%

“…These agents include the human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV), hepatitis E virus, Treponema pallidum, Trypanosoma cruzi and brucei (T. brucei brucei and T. brucei gambiense), Cytomegalovirus, Human T lymphocyte virus, etc. [4] [5] [6] [8] [9] [10] [11]. In this study, research is being conducted on the hepatitis B virus (hepatotropic Hepadnaviridae family) in blood donors.…”

Section: Introductionmentioning

confidence: 99%

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Seroprevalence of Hepatitis B Virus Infection (HBsAg) in Rural Blood Donors, Moba, Tanganyika Province, Democratic Republic of Congo (2014 to 2016)

Kabemba¹,

Kasendue²,

Shiku³

et al. 2017

OALib

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Blood transfusion is a salutary practice in modern medicine, but it carries a high risk of transmission of transfusion transmitted infections (TTIs), especially in developing countries. The objective of this study is to determine the seroprevalence of viral hepatitis B among blood donors. This is a retrospective and descriptive cross-sectional study of the period from 2014 to 2016 at the Katele Health Reference Center (Moba, DR. Congo). We investigated HBsAg in blood donors by using Determine ® HBSAg. 1145 blood donors with an age mean of 30.6 ± 6.9 years and predominantly male (62.5%) were retained.

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Section: /15mentioning

confidence: 99%

Section: /15mentioning

confidence: 99%

Section: The Seroprevalence Of Hbv Infection In Blood Donorsmentioning

confidence: 99%

Section: Viral Hepatitis B (Hvb) Is An Inflammation Of the Liver Withmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Seroprevalence of Hepatitis B Virus Infection (HBsAg) in Rural Blood Donors, Moba, Tanganyika Province, Democratic Republic of Congo (2014 to 2016)

Kabemba¹,

Kasendue²,

Shiku³

et al. 2017

OALib

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Estimating the Transmission Risks of Viral Hepatitis and HIV Among Blood Donors in Hossana, Southern Ethiopia

Beykaso¹,

Teklehaymanot²,

Giday³

et al. 2021

RMHP

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Screening of viral transfusion-transmissible infections (TTIs) among blood donors is of public health concern. It is a cost-effective method to monitor the occurrence, distribution, and trends of TTIs in healthy people. This study aimed to estimate the magnitude of the three common viral TTIs among blood donors in Hossana, Ethiopia. Methods: A cross-sectional study was conducted among 417 blood donors from April to May 2020 in Southern Ethiopia. Data were collected using a structured questionnaire and laboratory blood screening for hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) using Wantai AiDTM HBsAg, anti-HCV, and HIV 1 + 2 Ag/ Ab ELISA. Data were entered into Epi-Data version 3.1 and analyzed using SPSS version 21.0. A binary logistic regression model was fitted to identify factors associated with each viral infection. The odds ratio with a 95% confidence interval was calculated. A p-value <0.05 was considered statistically significant. Results: A total of 417 blood donors participated in this study producing an overall prevalence of viral TTI was 14.38%. HBV, HCV, and HIV prevalence were 9.83%, 2.39%, and 4.31%, respectively. HBV-HIV was a common co-infection, which had 1.2%. In multivariate logistic regression analysis, family history of hepatitis (AOR=5.2, 95% CI (2.92, 7.41)) and multiple sexual contacts (AOR=4.2, 95% CI (2.32-7.43)) were significantly associated with HBV; low educational level (AOR=3.1, 95% ) and multiple sexual contacts (AOR=4.9, 95% CI (3.51-7.96)) were significantly associated with HIV, but the only variable alcohol consumption (AOR=2.7, 95% CI (6.72-23.76)) was also associated with HCV infection. Conclusion:In this study, the magnitude of viral TTIs among blood donors is high. This indicates that there are high risks of transmission for these infectious pathogens. Therefore, effective stringent donor selection and screening protocols should be developed.

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Epidemiological Profile of Treponema pallidum Infection in Blood Donors Candidates at Moba, Tanganyika Province, Democratic Republic of Congo

Kabemba¹,

Kasendue²,

Shiku³

et al. 2017

OALib

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In sub-Saharan Africa, sexually transmitted infections (STIs) and transfusiontransmissible infections (TTIs) are a public health problem. Among them, we find the syphilis that the recipient of blood might contract in the absence of serological tests in the donor. The objective of this study was to determine the prevalence and profile of the individual at risk for transmission of Treponema pallidum among blood donation candidates. This is a single-center, retrospective and descriptive cross-sectional study over a period from 2015 to 2016 at the Katele Health Reference Center of Moba-Port in the Democratic Republic of Congo. The use of Rapid Plasma Reagin (RPR) was required for the detection of anti-treponematosis antibodies. The Epi Info 7.1 software was used to analyze the data at the significant threshold of p 0.05. Of 752 blood donors tested, 62.8% were male and the mean age was 30.3 ± 6.9 years with extremes ranging from 18 to 43 years. Family, replacement donors were the most encountered 2/13OALib Journal was encountered. The risk of contracting syphilis after transfusion remains high in our environment. It is mandatory to continue to research the Treponema pallidum in the serum of any blood donor. Education of the population on prevention of sexually transmitted infections and transfusion safety measures (especially during the donor screening phase) should be strengthened.

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Seroprevalence Hepatitis B in Blood Donors at Lubumbashi, DR Congo (Case of Provincial Hospital Sendwe Reference)

Cited by 3 publications

References 7 publications

Seroprevalence of Hepatitis B Virus Infection (HBsAg) in Rural Blood Donors, Moba, Tanganyika Province, Democratic Republic of Congo (2014 to 2016)

Seroprevalence of Hepatitis B Virus Infection (HBsAg) in Rural Blood Donors, Moba, Tanganyika Province, Democratic Republic of Congo (2014 to 2016)

Estimating the Transmission Risks of Viral Hepatitis and HIV Among Blood Donors in Hossana, Southern Ethiopia

Epidemiological Profile of Treponema pallidum Infection in Blood Donors Candidates at Moba, Tanganyika Province, Democratic Republic of Congo

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