Seroprevalence of Hepatitis B Virus Infection and Its Associated Factors Among Blood Donors in Yemen

Al-Nwany, Naif Tawfeq; Ahmad, Norfazilah; Nawi, Azmawati Mohammed; Hassan, Mohd Rohaizat; Hod, Rozita; Baharom, Mazni

doi:10.21315/mjms2021.28.5.5

Cited by 4 publications

(2 citation statements)

References 24 publications

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“…The overall prevalence rate (2.4%) of HBsAg among blood donors in this study was analogous to the studies carried out in various locations such as Yemen (2.6%), 17 Ethiopia (2.6%), 18 and India (2.12%). 19 However, the seropositivity rate of the present study was higher than our previous study (1.9%).…”

Section: Discussionsupporting

confidence: 84%

Updated Seroprevalence of Hepatitis B Surface Antigen and Anti-Hepatitis Core Antibody Among Blood Donors in Yemen

Alzubiery¹,

Alharazi²,

Alcantara³

et al. 2022

IDR

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Purpose Hepatitis B virus (HBV) is one of the most common infectious pathogens worldwide. Various studies found a prevalence of HBV infection among blood donors ranging from 2% to 18%. Hence, this study aimed to provide an updated prevalence of HBsAg and anti-HBcAb among blood donors. Patients and Methods This was a cross-sectional study to investigate the donation records of blood donors in Sana’a, Yemen, over one year (January to December 2019). Eligible blood donors were included in the study. The serum samples of blood donors were tested for HBsAg and anti-HBcAb (IgG & IgM) using the electrochemiluminescence (ECL) and enzyme immunoassay (EIA) techniques. Results A total of 16,367 blood donors were recruited in this study, of whom 14,300 (87.4%) donated only once during this study (single, non-duplicated blood donors), while 2067 (12.6%) were repeated or duplicated. The overall prevalence of HBsAg and anti-HBcAb was 2.4% and 10.8%, respectively. Among single non-duplicated blood donors, HBsAg and Anti-HBcAb were 2.3% and 10.6% and 3.0% and 12.5% for repeated blood donors, respectively. There were statistically significant differences between HBsAg and Anti-HBcAb in terms of donor type and testing techniques. Conclusion The seroprevalence of HBsAg and anti-HBcAb among the blood donors was 2.0% and 10.3%, respectively. The ECL technique is more sensitive, has a lower error rate, and shows an advantage over the manual EIA technique. Duplicated blood donors influence the accuracy of the seroprevalence of HBsAg and anti-HBcAb.

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Section: Discussionsupporting

confidence: 84%

Updated Seroprevalence of Hepatitis B Surface Antigen and Anti-Hepatitis Core Antibody Among Blood Donors in Yemen

Alzubiery¹,

Alharazi²,

Alcantara³

et al. 2022

IDR

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“…The married group had higher chance for acquiring hepatitis Viruses from their partners. This was also supported by the study conducted in Yemen [39], which revealed high prevalence of HBsAg in married blood donors.…”

Section: Discussionsupporting

confidence: 66%

Seroprevalence of Hepatitis B Infection Among Blood Donors in the Western Zone of Tanzania

Marira,

Kimaro,

Sauli

2024

Preprint

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Background In the western zone of Tanzania, there is limited information for the prevalence of hepatitis B infection. In this study, we analyzed the dataset of blood donors to determine seroprevalence and socio-demographic factors related to Hepatitis B Virus infection among blood donors in the western regions of Tanzania. Material and Methods The study was a cross-sectional retrospective hospital-based. Data were retrieved from blood donor dataset given at the Zonal Blood Transfusion Center. Information analyzed from the dataset includes reported Transfusion Transmissible Infections (TTIs) including Hepatitis B, donor demographics, donor status, donor type, donation place, and the year of donation. This study focused on five years period from January 2018 to December 2022. The seroprevalence rates of hepatitis B surface antigen (HBsAg) were determined, and the univariate and multivariate analysis were conducted to determine association between infection and demographic risk factors under STATA version 15.1. Results A total of 9604 retrospective blood donors were screened. Majority (93.3%) were men, and most were under 45 years (89.6%). The overall, seroprevalence for HBsAg was 6.9% (661) in this study, with Katavi (7.8%) being relatively high in the study area. The highest HBsAg seroprevalence of 8.2%, was found to be in age group range of 35 to 44 years. In addition, Polygamist 9.5%, and drivers at 17.1% were shown to have relatively high seroprevalence in this case. Using multivariate analysis, the results indicate blood donors who were drivers (OR 5.44, 95% CI; 2.43 12.20, p < 0.001), and the first-time donors (OR 5.19, 95% CI 2.56 = 10.52, P 4 < 0.001), were highly associated with an increased chance of hepatitis B infection. Conclusion The findings demonstrate that; there is a high seroprevalence of HBV in western regions. These findings bring to the attention of more advocacy for HBV immunization for all persons at high risk, as it is the most effective way to prevent HBV infection.

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Prevalence of occult hepatitis B virus infection among patients receiving haemodialysis in Sana'a city

et al. 2022

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Seroprevalence of Hepatitis B Virus Infection and Its Associated Factors Among Blood Donors in Yemen

Cited by 4 publications

References 24 publications

Updated Seroprevalence of Hepatitis B Surface Antigen and Anti-Hepatitis Core Antibody Among Blood Donors in Yemen

Updated Seroprevalence of Hepatitis B Surface Antigen and Anti-Hepatitis Core Antibody Among Blood Donors in Yemen

Seroprevalence of Hepatitis B Infection Among Blood Donors in the Western Zone of Tanzania

Prevalence of occult hepatitis B virus infection among patients receiving haemodialysis in Sana'a city

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