Background: The emergence and spread of antibiotic resistance, as well as the evolution of new strains of disease causing agents, are of great concern to the global health community. Nowadays, reports have indicated that many of healthcare-associated, antimicrobial-resistant bacteria are not only multidrug resistant pathogens but also broadly drug-resistant and pandrug-resistant bacteria. Objective: This study is focused on exploring the antimicrobial properties of five different plants that are commonly being used as traditional medicines in Yemen against Gram positive, Gram negative bacteria and fungi. Methods: The antimicrobial potential of five different plant extracts was screened against selected human pathogenic bacteria and fungi. Methanolic extracts of Dodonaea viscose, Plantago lanceolata, Withania samnifera, Pulicaria crispa, and Rumex nervosus were subjected to a test of their antimicrobial properties by Modified Agar Diffusion and Minimum Inhibitory Concentration. Results: The results indicated that all the five plants extract showed antibacterial activity against a selected microorganism at a concentration of 60 mg/ml. The highest potential was observed in the extract of W. somnifera against S. taphyloccocus aureus, Pseudomonas aeruginosa, Proteus miarbilis and Candida albicans with zone of inhibition of 23 mm, 20.7 mm, 20 mm and 25.3 mm, respectively. R. nervosus also showed the highest MIC against test organisms. Only two medicinal plant Pulicaria crispa, and Rumex nervosus extracts showed non antifungal activity. Conclusion: The experiment confirmed the efficacy of some selected plant extracts as natural antimicrobial and can be potential sources for the synthesis of antibacterial drugs.
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).
Background: Rubella is an infectious viral disease that caused by the Rubella virus. The incidence of rubella infection in women during pregnancy leads to complications for fetus development and cause congenital rubella syndrome or fetal death. This study aimed to determine the prevalence rate of rubella among reproductive-age women in Al-Mahweet, Yemen. Methods: A cross sectional study was conducted among females attending healthcare centers and schools from July 2007 to June 2008. Blood samples were collected individually from 270 females aged 15-35 years and the rubella virus IgG antibody was quantitated by enzyme-linked immunosorbent assay (ELISA). The needed data were collected by using a pretested questionnaire and analyzed by statistical program. Results: Overall, 197(73%) had IgG-positive antibody to rubella and 73(27%) had IgG-negative antibody to rubella. The highest rate of anti-rubella IgG was among females aged 15-25 years and the lowest was among the females aged 31-35 years. Similarly, the higher rate was among females living in urban area compared to females from rural area. The statistically significant difference was found between most educational levels and positive results of anti-rubella IgG. With regard to marital status, the most frequent of rubella antibody was 72.3%, 73.1%, and 75.0%, respectively, recorded among single, married, and divorced females. The non-pregnant women had (73.7%) more incidence to rubella IgG antibody than pregnant (66.7%). 82.2% of IgG- positive women had no history of stillbirth and 65% had a history of stillbirth. Conclusions: Most of the enrolled females had immunity against rubella virus, but still a significant percentage were susceptible to rubella infection. Thus, it is essential to introduce of rubella vaccine to control and prevent the rubella virus circulating among the community. Peer Review History: Received 20 July 2020; Revised 11 August; Accepted 22 August, Available online 15 September 2020 UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file Average Peer review marks at initial stage: 6.0/10 Average Peer review marks at publication stage: 8.0/10 Reviewer(s) detail: Name: Dr. (Mrs) Amaka A. Mgbahurike Affiliation: University of PortHarcourt, Nigeria E-mail: amaka_mgbahurike@yahoo.com Name: Dr. Tamer Elhabibi Affiliation: Egyptian Russian University, Egypt E-mail: Tamer_elhabibi@yahoo.com Name: Rawaa S. Al-Kayali Affiliation: Aleppo university, biochemistry and microbiology department, Syria E-mail: Rawah67@hotmail.com Name: Rola jadallah Affiliation: Arab American University, Palestine E-mail: rolla.jadallah@aaup.edu Comments of reviewer(s): Similar Articles: THE ASSOCIATION OF EPSTEIN-BARR VIRUS ANTIBODIES WITH RHEUMATOID ARTHRITIS AMONG YEMENI PATIENTS IN SANA’A CITY SEROPREVALENCE OF ANTI-MANNOSE BINDING LECTIN AUTOANTIBODIES IN PATIENTS WITH RHEUMATOID ARTHRITIS IN SANA'A CITY- YEMEN
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