Seroprevalence of Toxoplasma gondii infection in pet dogs in Lanzhou, Northwest China

Wu, Song-Ming; Huang, Si-Yang; Fu, Bao‐Quan; Liu, Guangyuan; Chen, Jiaxu; Chen, Mu-Xin; Yuan, Zihao; Zhou, Dong‐Hui; Weng, Ya-Biao; Zhu, Xing‐Quan; De-he, YE

doi:10.1186/1756-3305-4-64

Cited by 56 publications

(44 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The most common sources of human infection are ingestion of tissue cysts in raw or undercooked meat or of food or water contaminated with oocysts shed by felids and transplacental transmission [1]. T. gondii infection may cause serious disease in pregnant women and immunocompromised patients, such as AIDS patients and organ transplant recipients [2-6]. …”

Section: Introductionmentioning

confidence: 99%

Seroprevalence of Toxoplasma gondii in slaughtered horses and donkeys in Liaoning province, northeastern China

Yang

Yuan

et al. 2013

Parasites Vectors

View full text Add to dashboard Cite

BackgroundToxoplasma gondii is an important zoonotic pathogen infecting humans and almost all warm-blooded animals. The most common sources of human infection are ingestion of tissue cysts in raw or undercooked meat. However, limited information is available about T. gondii infection in horses and donkeys in China. In the present study, we report the seroprevalence of T. gondii infection in horses and donkeys in Liaoning province, northeastern China.MethodsSerum samples were collected from 711 and 738 slaughtered horses and donkeys, respectively, in 13 regions of Liaoning province. The modified agglutination test (MAT) was used to test the specific antibodies to T. gondii.ResultsIn this study, 178 of 711 (25.0%) horses were seropositive for T. gondii with titers of 1:25 in 81, 1:50 in 62, 1:100 in 33, and 1:200 in 2, and seroprevalence of T. gondii infection from 13 regions ranged from 8.2% to 37.0%. Antibodies to T. gondii were found in 174 of 738 (23.6%) donkeys with titers of 1:25 in 66, 1:50 in 54, 1:100 in 49, and 1:200 in 5, and seroprevalence varied in 13 different regions, ranging from 9.1% to 32.6%.ConclusionsThe results of the present study indicated that the rate of infection with T. gondii in horses and donkeys is a little high in Liaoning province, northeastern China in comparison to other surveys in China, which suggests that consumption of horse and donkey meat in this area may represent a potential source for human infection with T. gondii.

show abstract

Section: Introductionmentioning

confidence: 99%

Seroprevalence of Toxoplasma gondii in slaughtered horses and donkeys in Liaoning province, northeastern China

Yang

Yuan

et al. 2013

Parasites Vectors

View full text Add to dashboard Cite

show abstract

“…Antibodies to T. gondii were determined in house sparrow sera by the modified agglutination test (MAT) as described previously [19,20]. Briefly, sera were added to the "U" bottom of 96-well microtiter plates, and diluted 2-fold starting from 1:5 to 1:20.…”

mentioning

confidence: 99%

Prevalence and Genetic Characterization of Toxoplasma gondii in House Sparrows (Passer domesticus) in Lanzhou, China

et al. 2013

Self Cite

View full text Add to dashboard Cite

The prevalence of Toxoplasma gondii infection in birds has epidemiological significance because birds are indeed considered as a good indicator of environmental contamination by T. gondii oocysts. In this study, the prevalence of T. gondii in 313 house sparrows in Lanzhou, northwestern China was assayed by the modified agglutination test (MAT). Antibodies to T. gondii were positive in 39 (12.46%) of 313 samples (MAT titer ≥ 1:5). Tissues of heart, brain, and lung from the 39 seropositive house sparrows were tested for T. gondii DNA, 11 of which were found to be positive for the T. gondii B1 gene by PCR amplification. These positive DNA samples were typed at 9 genetic markers, including 8 nuclear loci, i.e., SAG1, 5'- and 3'-SAG2, alternative SAG2, SAG3, GRA6, L358, PK1, c22-8 and an apicoplast locus Apico. Of them, 4 isolates were genotyped with complete data for all loci, and 2 genotypes (Type II variants; ToxoDB #3 and a new genotype) were identified. These results showed that there is a potential risk for human infection with T. gondii in this region. To our knowledge, this is the first report of T. gondii seroprevalence in house sparrows in China.

show abstract

“…Differences in the prevalence of Demodex infection in pet dogs between different months, sexes and age groups were analyzed using a Chi square test within the SPSS for Windows (Release 18.0 standard version, SPSS Inc., Chicago, Illinois) (Wu et al, 2011;Zhao et al, 2011). The differences were considered statistically significant when P < 0.05.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Demodex infection in pet dogs in Southern China

Lin¹,

Zhou²,

Song³

et al. 2012

Afr. J. Microbiol. Res.

View full text Add to dashboard Cite

Canine demodicosis caused by ectoparasitic mites in the genus Demodex is a major and common ectoparasitic disease of dogs. However, little is known of the prevalence of Demodex infection in pet dogs in China. The present study was conducted to determine the prevalence of Demodex infection in pet dogs in Guangzhou, Southern China. A total of 3977 pet dogs admitted to several animal hospitals in Guangzhou City were investigated for Demodex infection from January to December 2009. The result showed that 977 (24.57%) dogs were positive for dermatosis and 130 (13.31%) of the dermopathic dogs were positive for Demodex infection. No significant association was found between Demodex prevalence and season, age, and gender of pet dogs. Seasonal prevalence showed that the highest and lowest were in March (4.15%) and December (1.39%), respectively. The prevalence in male dogs (3.67%) was higher than that in female dogs (2.74%). Dogs of 1 to 5 year old were more commonly infected than other age groups. The present investigation revealed the prevalence of Demodex infection in pet dogs in China's subtropical Guangzhou City, which accounts for 13.31% of canine dermatosis cases. These results have important implications for conducting control strategies and measures against canine demodicosis in this region.

show abstract

Seroprevalence of Toxoplasma gondii infection in pet dogs in Lanzhou, Northwest China

Cited by 56 publications

References 22 publications

Seroprevalence of Toxoplasma gondii in slaughtered horses and donkeys in Liaoning province, northeastern China

Seroprevalence of Toxoplasma gondii in slaughtered horses and donkeys in Liaoning province, northeastern China

Prevalence and Genetic Characterization of Toxoplasma gondii in House Sparrows (Passer domesticus) in Lanzhou, China

Prevalence of Demodex infection in pet dogs in Southern China

Contact Info

Product

Resources

About