Seroprevalence of Toxoplasmosis in Pregnant Women in a City in Rio Grande Do Norte State, Brazil

Freitas, Laura Christina; Marques, Michael Radan de Vasconcelos; Leite, Ranny Beatriz de Carvalho Holanda; Holanda, Cecília Maria de Carvalho Xavier; Barbosa, Vanessa Santos de Arruda

doi:10.5216/rpt.v46i2.47453

Cited by 4 publications

(1 citation statement)

References 22 publications

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“…In this study, a high prevalence of 66.2% was found for anti-T. gondii IgG antibodies in residents of the municipality of Santa Cruz, RN. Surveys carried out in other northeastern areas also showed a high seroprevalence of 66.4% in São Luis, MA (Costa et al, 2010), 87.4% in Joao Pessoa, PB (Junior & Monteiro., 2010), and 59% in Jaçana, RN (Freitas et al, 2017). Interestingly, seroprevalence did not vary considerably according to family income, as noted in other studies (Dias et al, 2011;Lopes-Mori et al, 2013;Benitéz et al 2017).…”

Section: Discussionsupporting

confidence: 64%

Seroprevalence and Risk Factors for Human Toxoplasmosis in Northeastern Brazil

Aloise¹,

Coura‐Vital²,

Carneiro³

et al. 2018

Rev Patol Trop

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Toxoplasmosis is one of the most prevalent parasitic infections in humans, causing severe clinical complications in immunocompromised patients or in foetuses. Estimates on the toxoplasmosis seroprevalence in human populations vary widely, even within the same region. This study aimed to estimate the prevalence of Toxoplasma gondii infection in the municipality of Santa Cruz, State of Rio Grande do Norte, Brazil, and identify the risk factors for toxoplasmosis. T. gondii IgG antibodies were measured in 66.2% of the studied population. The factors associated with infection were as follows: age above 45 years (OR = 7.4; 95% CI = 3.7-14.8); illiteracy (OR = 2.8; 95% CI = 1.6-5.0); the presence of more than three cats in the home (OR 2.0; 95% CI = 1.2-3.5); no water tank (OR = 2.0; 95% CI = 1.4-3.1); and consumption of raw or unpasteurized milk (OR = 2.0; 95% CI = 1.3-3.0). The risk factors identified were predominantly related to the ingestion of oocysts. This study may contribute to public health knowledge of toxoplasmosis and the definition of control programs, particularly for pregnant women from regions similar to the area studied.

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Section: Discussionsupporting

confidence: 64%

Seroprevalence and Risk Factors for Human Toxoplasmosis in Northeastern Brazil

Aloise¹,

Coura‐Vital²,

Carneiro³

et al. 2018

Rev Patol Trop

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Genetic polymorphism in IL17RA induces susceptibility to Toxoplasma gondii infection in Brazilian pregnant women

Andrade¹,

Oliveira

Meurer

et al. 2020

Acta Tropica

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Serological study on toxoplasmosis in the Haliti-Paresí community of the Utiariti indigenous territory, Campo Novo do Parecis, Mato Grosso, Brazil

Santos

Terças-Trettel

Ribeiro

et al. 2019

Parasite Epidemiology and Control

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Toxoplasma gondii is the etiological agent of toxoplasmosis, a widespread zoonosis that affects several homeothermic animals, including humans. This disease causes serious health problems, such that 10% of infected individuals develop clinical manifestations. Some studies on indigenous human populations have indicated variations in seroprevalence from 10.6% to 80.4% in such populations in different regions of Brazil and in other countries like Venezuela and Malaysia. To date, there have been no studies regarding the prevalence of anti- T. gondii antibodies in Haliti-Paresí Indians living in Campo Novo do Parecis, Mato Grosso, Brazil. Our objective here was to determine the frequency of occurrence of antibodies against this protozoon in nine Haliti-Paresí villages by correlating seroprevalence with locations and variables. Serodiagnoses were made using the indirect immunofluorescence antibody test (IFAT) and enzyme-linked immunosorbent assay (ELISA) in the Laboratory for Toxoplasmosis and Other Protozoan Diseases of IOC/Fiocruz. It was considered that samples tested positive for T. gondii infection if IgG/IgM antibodies against this protozoon were detected through serodiagnosis using either IFAT or ELISA. Among the 293 samples analyzed, 66.9% presented anti- T. gondii IgG and 3.4% presented anti- T. gondii IgM. It was observed that there were no statistically significant differences in frequency of antibody occurrence among infected individuals, based on sex, schooling or occupation/activities. However, there were statistical differences based on age and villages. The prevalence observed in this study is in agreement with values found in other studies on indigenous populations in Latin America. Like among other such populations, the Haliti-Paresí villages are located close to forests and the individuals have domestic cats as pets, are involved in hunting and farming and consume water directly from water accumulation sources. These factors might cause exposure to T. gondii tissue cysts and oocysts.

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Seroprevalence of Toxoplasmosis in Pregnant Women in a City in Rio Grande Do Norte State, Brazil

Cited by 4 publications

References 22 publications

Seroprevalence and Risk Factors for Human Toxoplasmosis in Northeastern Brazil

Seroprevalence and Risk Factors for Human Toxoplasmosis in Northeastern Brazil

Genetic polymorphism in IL17RA induces susceptibility to Toxoplasma gondii infection in Brazilian pregnant women

Serological study on toxoplasmosis in the Haliti-Paresí community of the Utiariti indigenous territory, Campo Novo do Parecis, Mato Grosso, Brazil

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