Seroprevalence of Varicella in the French Population

Khoshnood, Babak; Debruyne, Monique; Lançon, Florian; Émery, C.; Fagnani, Francis; Durand, Isabelle; Floret, D.

doi:10.1097/01.inf.0000195636.43584.bb

Cited by 48 publications

(29 citation statements)

References 14 publications

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“…Furthermore, our estimates of cumulative incidence of varicella at age 11 years are similar to that of a recent independent French seroprevalence study (90 % at age 11 years [24]) as well as earlier figures in France [25]. However, the cumulative incidence in Corsica appeared to be shifted towards higher ages, by <1 year, compared to those reported in continental France [24]. This may be due to our correct handling of age in our models, expressed in completed years using methods for interval-censored data ; but it could also be the consequence of a lower population density in Corsica in relation to other French regions.…”

Section: Discussionsupporting

confidence: 86%

Micro and macro population effects in disease transmission: the case of varicella

et al. 2009

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SUMMARYProfiles of varicella-zoster virus (VZV) seroprevalence have shown large variability in European countries in which vaccination has not been implemented. Differences in micro and macro population structures (e.g. household and municipality, respectively) may explain such variability, which is the focus of a population-based study of varicella in 12 000 children from 7800 French households in Corsica. The cumulative incidence was 89 % at age 11 years, as the median age at infection was 5 years in first-born children, but decreased to 3 . 9 years in younger siblings. Hazard of infection in households increased as the first-born child initially enrolled in primary school. Age at infection was higher in less populated areas. Household attack rates increased with age (55 % in <6 months, >90 % in >3 years) and household secondary attack rate was y70 %. Several levels of population structure independently affect age at varicella infection.

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Section: Discussionsupporting

confidence: 86%

Micro and macro population effects in disease transmission: the case of varicella

et al. 2009

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“…This is in line with data regarding the seroprevalence of anti-VZV antibodies in the French population (11). In another study conducted in France at the end of 2005, 1.2% of 486 pregnant women included were seronegative for VZV (20).…”

Section: Discussionsupporting

confidence: 67%

“…In France, an age-specific prevalence study reported seroprevalence rates of about 50% by the age of 4 years and 90% by 8 years (11). The disease is usually benign but may lead to severe complications and occasionally death (6,17).…”

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confidence: 99%

Prevalence of Anti-Varicella-Zoster Virus Antibodies in French Infants under 15 Months of Age

Pinquier¹,

Gagneur

Balu

et al. 2009

Clin Vaccine Immunol

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“…Cependant, la séroprévalence de la varicelle chez les professionnels de santé est d'au moins 98 % et la mise en oeuvre d'une obligation se heurterait au fait que la majorité des personnels en poste se souviennent avoir fait la varicelle, sans pouvoir en apporter la preuve, sauf à pratiquer une sérologie 36 . Pour ces raisons, le maintien d'une recommandation forte pour les professionnels non immunisés, telle qu'elle existe actuellement, parait plus adapté.…”

Section: La Vaccination Des Professionnels De Santéunclassified