Serratia Keratitis Transmitted by Contaminated Eyedroppers

Pseudomonas aeruginosaGrowth in Refresh Plus®

“…Pseudomonas and Serratia keratitis transmitted by contaminated eye drops have been described. [17][18][19] In a recent survey, the rate of microbial contamination in multiple-use preservative-free artificial tears packed in reclosable containers was found to be 2%; advanced age and fingertip touch were statistically significant risk factors for bacterial contamination. 20 Reuse of unit-dose vials is relatively common in patients with dry eye, Meibomian gland dysfunction, and contact lens wearers.…”

Clinical Administration of Ocular Drugs

“…Solutions or sus pensions are usually preferred over ointments, since the former are more easily instilled, interfere less with vision, and have fewer potential complications. 29 Dis advantages of topically applied solutions, however, include short ocular contact time, 29 imprecise and in consistent delivery of drug, frequent contamination, 30 and the possibility of ocular injury with the dropper tip. 3132 Furthermore, aqueous suspensions have the problem of precipitation.…”

Contaminação de frascos de colírios de soro autólogo

“…Autologous serum eyedropper contamination after topical use (1) Prof. Adjunto e Chefe do laboratório de Microbiologia do Departamento de Oftalmologia da UNIFESP/EPM. (2) Farmacêutico -Pós-graduando nível doutorado do Departamento de Oftalmologia da UNIFESP/EPM (3) Farmacêutico -Chefe do Laboratório Oftalmolab.…”

“…São Paulo (SP) CEP 04524-020. E-mail: coftalmo@uol.com.br Ana Luisa Höfling-Lima (1) Acácio Souza Lima (2) José Antonio Batistoso (3) Débora Kawamura (4) Maria Regina Catai Chalita (5) Leandro Siqueira Alves (5) Michel Eid Farah (6) RESUMO INTRODUÇÃO Na literatura oftalmológica encontramos casos descritos de infecções oculares bacterianas transmitidas por colírios contaminados 1,2 . A manutenção da esterilização dos medicamentos usados topicamente é importante visto que em muitas situações pode haver uma modificação da defesa natural do próprio paciente 3,4 .…”