Serratia marcescens Septicemia

Extended Epidemic of Nosocomial Urinary Tract Infections Caused by Serratia marcescens

“…As shown in Fig. 1, the annual number of S. marcescens isolates increased steadily, from 749 in 1991 to 991 in 1995, followed by a rapid increase to 1,450 The number of urinary isolates of S. marcescens also increased, from 159 in 1991 to 299 in 1995, followed by a sudden upsurge to 688 in 1996, and then gradually decreased to 134 in 2002 ( Fig. 1).…”

“…Its pathogenicity for humans was first noted in 1913 (31); however, the prevalence of S. marcescens in human diseases had been underestimated for years before the first known outbreak of nosocomial S. marcescens infections in 1951 (30). Since 1960, infections with this organism have been reported with increasing frequency (1,7,24).…”

An outbreak of multidrug-resistant Serratia marcescens: the importance of continuous monitoring of nosocomial infections

“…The first description of nosocomial infection caused by Serratia marcescens was Wheat's report of 11 cases over a 6-month period in 1951 at Stanford University Hospital (3). Infections caused by this organism have been reported with increasing frequency since 1960 (4). Since the emergence of Serratia marcescens as a cause of infections was noticed, many aspects of the pathogenicity and virulence of the organism have been studied, including adherence and hydrophobicity, lipopolisaccharide (LPS) and extracellular products (chitinase, several proteases, nuclease and lipase) (2).…”

“…Outbreaks have been traced to multiple sources, including contaminated solutions and disinfectants, intravenous fluids, mechanical respirators, intravenous catheters, ultrasonic nebulizers, fiberoptic bronchoscopes, and hand-to-hand transmission by hospital personnel (4)(5)(6)(7).…”

<i>Serratia marcescens</i> as Opportunistic Pathogen and the Importance of Continuous Monitoring of Nosocomial Infection in Makah City, Saudi Arabia

“…The first description of nosocomial infection caused by Serratia marcescens was Wheat's report of 11 cases over a 6-month period in 1951 at Stanford University Hospital [4]. Infections caused by this organism have been reported with increasing frequency since 1960 [5]. Serratia marcescens has expressed the ability to survive and grow under extreme conditions, including in disinfectants, antiseptics and double-distilled water [6].…”