Serum adiponectin, interleukin-10 levels and inflammatory markers in the metabolic syndrome

Choi, Kyung Mook; Ryu, Ohk Hyun; Lee, K.W.; Kim, H.Y.; Seo, Ji A; Kim, S.G.; Kim, N.H.; Choi, Dong Seop; Baik, Sei Hyun

doi:10.1016/j.diabres.2006.06.019

Cited by 108 publications

(98 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In these cells, adiponectin reduces lipopolysaccharides stimulated TNF alpha production. Recent clinical trials show a positive correlation of plasma levels of adiponectin and IL 10 [5]. In accordance with these findings, adiponectin has an antiatherogenic properties in mice Adiponectin: A Perspective Adipose Tissue Marker with Antiinflammatory and Antiaterogenic Potencial 679 models.…”

Section: Adiponectin and Atherosclerosissupporting

confidence: 62%

Adiponectin: A Perspective Adipose Tissue Marker with Antiinflammatory and Antiaterogenic Potencial

Novotny¹,

Vaverková²,

Karásek³

2012

Lipoproteins - Role in Health and Diseases

View full text Add to dashboard Cite

Section: Adiponectin and Atherosclerosissupporting

confidence: 62%

Adiponectin: A Perspective Adipose Tissue Marker with Antiinflammatory and Antiaterogenic Potencial

Novotny¹,

Vaverková²,

Karásek³

2012

Lipoproteins - Role in Health and Diseases

View full text Add to dashboard Cite

“…Показано также, что у больных с метаболиче-ским синдромом уровень ИЛ-10 снижен, что ассоци-ировано с повышением АД [10]. По-видимому, ассо-циация уровня ИЛ-10 и регуляции сосудистого тонуса может быть связана с тем, что ИЛ-10 способствует экспрессии NO-синтетазы.…”

Section: Discussionunclassified

Left Ventricular Hypertrophy Development, Associated With Genetic Polymorphism of Inflammatory Mediators

Минушкина¹,

Чумакова²,

Selezneva³

et al. 2015

Ross. kardiol. ž.

View full text Add to dashboard Cite

“…Recently, a positive correlation between serum IL-10 and hs-CRP levels was reported in 312 Korean individuals including 269 women. 23 Serum levels of IL-10 are likely to correlate positively with serum levels of inflammatory factors despite its anti-inflammatory properties. As shown in the present study, an elevation of serum IL-10 might be a compensatory reaction for pro-inflammatory activation in healthy subjects.…”

Section: Discussionmentioning

confidence: 99%

Interleukin-10 Associates With Adiponectin Predominantly in Subjects With Metabolic Syndrome

Nishida

Moriyama

Sugita

et al. 2007

Circ J

View full text Add to dashboard Cite

Background Inflammation and the metabolic syndrome (MetS) are important risk factors in cardiovascular disease. There is accumulating evidence that decreased adiponectin levels are associated with MetS. Recently, it was shown that adiponectin induces the expression of a potent anti-inflammatory cytokine, interleukin (IL)-10, in vitro. The aim of this study is to investigate the association of IL-10 levels with other pro-inflammatory and anti-inflammatory factors including adiponectin levels in vivo. Methods and Results MetS components were assessed in 117 drug-naïve middle-aged men. Serum levels of high-sensitive C-reactive protein (hs-CRP), IL-6, adiponectin, IL-10 and tumor necrosis factor-(TNF-) were measured in these subjects. A significant decrease in adiponectin (5.15±1.79 g/ml vs 6.87±3.55 g/ml, p<0.02) and an increase in IL-6 (1.50±1.50 pg/ml vs 1.06±0.78 pg/ml, p<0.05) levels were associated with MetS. The serum IL-10 level exhibited a significant positive correlation with IL-6, hs-CRP, and TNF-levels, but not with adiponectin in healthy individuals. However, IL-10 exhibited a significant correlation with adiponectin, especially in the subjects with MetS. Conclusions Serum IL-10 levels correlated with inflammatory proteins, but not with adiponectin. However, IL-10 positively associated with adiponectin especially in the subjects with MetS. IL-10 might be involved in the inflammatory network of MetS in relation to adiponectin. (Circ J 2007; 71: 1234 -1238

show abstract

Serum adiponectin, interleukin-10 levels and inflammatory markers in the metabolic syndrome

Cited by 108 publications

References 28 publications

Adiponectin: A Perspective Adipose Tissue Marker with Antiinflammatory and Antiaterogenic Potencial

Adiponectin: A Perspective Adipose Tissue Marker with Antiinflammatory and Antiaterogenic Potencial

Left Ventricular Hypertrophy Development, Associated With Genetic Polymorphism of Inflammatory Mediators

Interleukin-10 Associates With Adiponectin Predominantly in Subjects With Metabolic Syndrome

Contact Info

Product

Resources

About