Serum amylase and lipase activities in normal pregnancy: a prospective case-control study

Karsenti, David; Bacq, Yannick; Bréchot, Jean-François; Mariotte, N.; Vol, Sylviane; Tichet, Jean

doi:10.1111/j.1572-0241.2001.03607.x

Cited by 22 publications

(13 citation statements)

References 9 publications

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“…The level of serum lipase was lesser when it was compared to control. A study conducted by Karsenti et al 15 observed that the serum lipase activity was decreased during first trimester and mechanism behind this is not known. In this study the level of serum amylase in nonpregnant women (69.66 ± 16.45 U/L) when compared to the case of hyperemesis gravidarum (76.40 ± 33.86U/L) was also not statistically significant (p=0.210) as shown in Table 2.…”

Section: Discussionmentioning

confidence: 98%

Study of serum lipase level in pregnant woman presenting with nausea and vomiting

et al. 2019

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Background: Hyperemesis gravidarum is a complex condition characterized by excessive nausea and vomiting during pregnancy. It presents with various symptoms which include disturbed nutrition, electrolyte imbalance, ketosis and extreme weight loss. The objective of this study is to compare serum lipase, amylase and glucose in Hyperemesis gravidarum with non-pregnant women. Materials and methods: A total of 100 subjects among which 50 were nonpregnant women as controls and 50 were women with hyperemesis gravidarum as cases were enrolled in the study. Serum lipase, amylase and glucose levels were estimated in all the subjects. Results: The levels of mean serum lipase were lesser in cases (23.55 ± 4.91U/L) compared to that in controls (25.45 ± 5.97U/L) with p=0.086. However, the levels of mean serum amylase were higher in cases (76.40 ± 33.86 U/L) compared to that in controls (69.66 ± 16.45U/L) with p= 0.210. Serum amylase activity was raised in 8% of the patients whereas the activity of pancreatic lipase was within normal range. Serum glucose levels were lower in cases (84.72 ± 11.28 mg/dl) than that in controls (87.04 ± 10.65 mg/dl) with p=0.293. Conclusions: From this study we conclude that lipase activity was statistically insignificant in hyperemesis gravidarum. Therefore, pancreatic activities were less affected by hyperemesis gravidarum. So, this condition needs further exploration regarding biochemical basis to minimize the risk associated with it.

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Section: Discussionmentioning

confidence: 98%

Study of serum lipase level in pregnant woman presenting with nausea and vomiting

et al. 2019

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“…Serum amylase activity does not change significantly during pregnancy. 65,72,77 Serum lipase activity is significantly lower in first trimester but not in second and third trimesters compared with nonpregnant women. 77 Important causes of acutely elevated transaminases in pregnancy include PET/HELLP, drug reactions, AFLP, viral and autoimmune hepatitis, sepsis, hyperemesis gravidarum and intrahepatic cholestasis of pregnancy (ICP).…”

Section: Liver Testsmentioning

confidence: 98%

“…Serum amylase activity does not change significantly during pregnancy . Serum lipase activity is significantly lower in first trimester but not in second and third trimesters compared with non‐pregnant women …”

Section: Laboratory Investigationsmentioning

confidence: 99%

Review article: Investigations and the pregnant woman in the emergency department – part 1: Laboratory investigations

Morton

Teasdale

2018

Emerg Medicine Australasia

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Accurate assessment of the pregnant patient in the ED depends on knowledge of physiological changes in pregnancy, and how these changes may impact on pathology tests, appearance on point‐of‐care ultrasound and electrocardiography. In addition the emergency physician needs to be cognisant of disorders that are unique to or more common in pregnancy. Part 1 of this review addresses potential deviations in laboratory investigation reference intervals resulting from physiological alterations in pregnancy, and the important causes of abnormal laboratory results in pregnancy. Part 2 will address the role of point‐of‐care ultrasound in pregnancy, physiological changes that may affect interpretation of point‐of‐care ultrasound, physiological changes in electrocardiography, and the safety of radiological procedures in the pregnant patient.

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“…La lipasa tiene la ventaja de ser más específica y de permanecer elevada por más tiempo que la amilasa (Working Group IAP/APA, 2013; Sarr, 2013). Se ha reportado que en embarazos normales los niveles de estas enzimas permanecen normales o muy levemente elevados (Karsenti et al, 2001;Larsson et al, 2008). (Garel et al, 1998;Uribe et al, 2009).…”

Section: Consideraciones Diagnósticas En El Embarazounclassified

Manejo de la pancreatitis aguda litiásica en la embarazada

Fernandez¹,

Carvajal²,

E³

et al. 2017

ARS med

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La pancreatitis aguda (PA) es una patología poco frecuente durante el embarazo, siendo la colelitiasis una de sus principales etiologías y Chile uno de los países con más altas prevalencias de colelitiasis en el mundo. Esta patología clásicamente ha reportado altas tasas de mortalidad materno-fetal, así como también riesgo de morbilidad fetal. Sin embargo, gracias a los avances en terapia de soporte y mejoras en unidades de neonatología, en la actualidad el pronóstico con un adecuado tratamiento es alentador. Nos parece imperativo tener protocolos adecuados de toma de decisión en la embarazada con pancreatitis aguda, puesto que, a pesar de ser una patología de baja prevalencia, un correcto enfrentamiento puede mejorar el resultado materno-fetal. El presente trabajo propone una guía de manejo clínico interdisciplinario de la embarazada con pancreatitis y aporta una revisión actual sobre este tema. Palabras clave: pancreatitis aguda; el embarazo; pancreatitis en el embarazo.

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Serum amylase and lipase activities in normal pregnancy: a prospective case-control study

Abstract: An increase in serum amylase and lipase activities during pregnancy should be taken into account, as in nonpregnant women.

Cited by 22 publications

References 9 publications

Study of serum lipase level in pregnant woman presenting with nausea and vomiting

Study of serum lipase level in pregnant woman presenting with nausea and vomiting

Review article: Investigations and the pregnant woman in the emergency department – part 1: Laboratory investigations

Manejo de la pancreatitis aguda litiásica en la embarazada

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