Serum Calcium Status of Neonates with Seizure in a Tertiary Care Hospital

Baten, Olia Sharmeen; Mollah, Abid Hossain; Ali, Mohammad Nawsher; Rashid, Mohammod Hasanur

doi:10.3329/bjch.v36i3.14274

Cited by 2 publications

(9 citation statements)

References 8 publications

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“…This is in contrast to present and previous studies. 6,8,13 In present study, 11% of controls were suffering from hypocalcemia that is comparable to the Baten et al 13 that noted in 20% of control. In present study, the duration of <5 minutes seizures in controls were noted in 7 and in cases in 73.…”

Section: Discussionsupporting

confidence: 88%

“…This frequency is very small and is inconsistent with present and previous studies. 8,13 Approximately, 94 controls showed convulsion frequency of <1 while 84 cases showed ≥4 convulsions (p=0.0001). Nature of convulsions was; focal in 37%, subtle in 31% and mixed in 32% of cases.…”

Section: Discussionmentioning

confidence: 99%

“…7,8 Various cut off values are defined such as serum Ca++ <8 mg/dl 8 , <7.5 mg/dl and < 7 mg/dl. 6,7 Baten et al 13 conducted a study on serum calcium levels in neonatal seizures with 50 cases and reported hypocalcemia in 60% of cases. The finding is in agreement with present however, less percentage of above study 13 may be due to small sample size.…”

Section: Discussionmentioning

confidence: 99%

“…The findings are in agreement with previous studies. 7,13 Duration of neonatal seizure of > 30 minutes indicates poor prognosis. 7,13 In present study majority of cases were having duration of seizure of <5 minutes that is consistent with a previous study.…”

Section: Discussionmentioning

confidence: 99%

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Serum calcium level in neonatal seizures presenting at a Tertiary Care Hospital.

Maheshwari¹,

Noor²,

Bashir³

et al. 2021

TPMJ

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Objectives: The present study was conducted to detect serum calcium level in neonatal seizures presenting at a Tertiary Care Hospital. Study Design: Case control study. Setting: Department of Paediatrics, Shaheed Muhtrama Benazir Bhutto Medical. College Layari General Hospital, Karachi, Sindh. Period: June 2017 to January 2018. Material & Methods: The sample comprised of 100 cases and 100 controls that were selected through non- probability purposive sampling through inclusion and exclusion criteria. Sera were separated through centrifugation of blood for measuring the serum calcium levels. Data was analyzed on SPSS software (SPSS ver 22.0, IBM, Incorporation, USA) at 95% confidence interval (P≤0.05). Results: Of 100 cases and 100 controls, the male and female were noted as 61 vs. 57 and 39 vs. 43 respectively (P > 0.05). In cases, the mean± SD Ca++ was noted as 4.17±1.58 mg/dl while in control it was noted as 8.15± 1.05 mg/dl. Ca++ levels as low as 3.07 mg/dl were noted in the neonatal seizure cases. Normocalcaemia was noted in 81 controls vs. 11 cases and hypocalcaemia in 18 controls vs. 89 cases. Conclusion: The present study reports hypocalcemia is common in neonatal seizures. Pediatricians must evaluate for timely correction of serum calcium to prevent long term neurological sequelies.

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Section: Discussionsupporting

confidence: 88%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Serum calcium level in neonatal seizures presenting at a Tertiary Care Hospital.

Maheshwari¹,

Noor²,

Bashir³

et al. 2021

TPMJ

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“…Local data on the relationship between calcium or vitamin D and other outcomes in young children are limited. Baten et al 85 conducted a case–control study of 50 healthy neonates and 50 with recent idiopathic convulsions in Dhaka, measured serum calcium, and determined 60% of cases and 20% of controls were hypocalcemic (mean serum concentration was 6.48 vs 8.28 mg/dL, respectively). In a case–control study of 87 hypocalcaemic and 246 normocalcaemic severely malnourished children admitted to a Dhaka ICU, Chisti et al 86 found a 26% prevalence of hypocalcaemia; acute watery diarrhea, convulsions, and lethargy were independent predictors of hypocalcaemia in this population.…”

Section: Consequencesmentioning

confidence: 99%

Calcium Deficiency in Bangladesh

2016

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Background Bangladesh incurs among the highest prevalence of stunting and micronutrient deficiencies in the world, despite efforts against diarrheal disease, respiratory infections, and protein energy malnutrition which have led to substantial and continuous reductions in child mortality over the past 35 years. Although programs have generally paid more attention to other micronutrients, the local importance of calcium to health has been less recognized. Objective To synthesize available information on calcium deficiency in Bangladesh in order to inform the design of an effective national calcium program. Methods We searched 3 online databases and a multitude of survey reports to conduct a narrative review of calcium epidemiology in Bangladesh, including population intake, determinants and consequences of deficiency, and tested interventions, with particular reference to young children and women of childbearing age. This was supplemented with secondary analysis of a national household survey in order to map the relative extent of calcium adequacy among different demographics. Results Intake of calcium is low in the general population of Bangladesh, with potentially serious and persistent effects on public health. These effects are especially pertinent to young children and reproductive-age women, by virtue of increased physiologic needs, disproportionately poor access to dietary calcium sources, and a confluence of other local determinants of calcium status in these groups. Conclusion A tablet supplementation program for pregnant women is an appealing approach for the reduction in preeclampsia and preterm birth. Further research is warranted to address the comparative benefit of different promising approaches in children for the prevention of rickets.

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Serum Calcium Status of Neonates with Seizure in a Tertiary Care Hospital

Abstract: Background: Seizure is a common neurological disorder in neonatal age group. Primary metabolic derangement is one of the common reason behind this convulsion during this period. Among metabolic abnormalities, hypocalcaemia is most common followed by hypoglycemia and hypomagnesaemia.

Cited by 2 publications

References 8 publications

Serum calcium level in neonatal seizures presenting at a Tertiary Care Hospital.

Serum calcium level in neonatal seizures presenting at a Tertiary Care Hospital.

Calcium Deficiency in Bangladesh

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