Serum Creatinine Determined by Jaffe, Enzymatic Method, and Isotope Dilution‐Liquid Chromatography‐Mass Spectrometry in Patients Under Hemodialysis

Liu, Wen Sheng; Chung, Yu Ting; Yang, Chih Yu; Lin, Chih Ching; Tsai, Kun Hung; Wu, Yang Chang; Chen, Tzen Wen; Lai, Yen-Ting; Li, Szu Yuan; Liu, Tsung Yun

doi:10.1002/jcla.21495

Cited by 50 publications

(33 citation statements)

References 19 publications

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“…34 Liu et al have compared the estimated performance of Jaffe and enzymatic methods and suggested that the latter was better. 35 It is a consensus to monitoring trough vancomycin concentration in clinical settings when multiple serum concentrations to determine AUC are difficult to obtain. The results of this study did not show a significant difference in prediction between peak and trough concentrations except for Roberts' model.…”

Section: (A) (B)mentioning

confidence: 99%

Predictive performance of reported population pharmacokinetic models of vancomycin in Chinese adult patients

Deng

Liu

et al. 2013

J Clin Pharm Ther

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SUMMARYWhat is known and objective: There are numerous studies on population pharmacokinetics of vancomycin in adult patients. However, there is no such research for Chinese adult patients. This study was conducted to evaluate the predictive performance of reported population pharmacokinetic models of vancomycin in Chinese adult patients and to identify some models appropriate for our population. Methods: A literature search was conducted in PubMed to obtain the population pharmacokinetic models of vancomycin published between December 2010 and September 2012. The models were assessed using concentration data collected from Chinese patients for external validation. Models with relatively poor predictability were excluded from further analysis. The performance of the remaining models was evaluated in patients with different levels of creatinine clearance, age, body weight and sex by Bayesian method. This method was also used to compare the predictive performance based on peak concentration and trough concentration and the predictability based on different number of observed concentrations. Results: One hundred and sixty-five blood concentrations from 72 Chinese adult patients were collected retrospectively to serve as the test data set. The evaluated models included all those reported in the seven publications reviewed by Marsot et al. and three other studies published after December 2010. Three models with poor performance on external validation were excluded from the next Bayesian analysis. The distribution of covariates in the model building data set had an important effect on prediction. The predictability based on peak/trough concentration was similar among the evaluated models, and no significant difference was found using our data set except for Roberts' model. As expected, an increased number of samples improved the performance of the Bayesian prediction. What is new and conclusion: With our data set, the performance of the evaluated models varied. The characteristics of the patient population and distribution of covariates should be given more consideration when choosing a model to predict blood concentrations. The model developed by Purwonugroho et al. using a data set from patients similar to ours is appropriate for Bayesian dose predictions for vancomycin concentrations in our population of Chinese adult patients. WHAT IS KNOWN AND OBJECTIVEVancomycin is a glycopeptide antibiotic, with time-dependent bacterial killing effect, which is used for therapy of infections caused by penicillinase-producing Staphylococcus aureus, especially methicillin-resistant Staphylococcus aureus (MRSA), Staphylococcus epidermis and Enterococcus faecalis.

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Section: (A) (B)mentioning

confidence: 99%

Predictive performance of reported population pharmacokinetic models of vancomycin in Chinese adult patients

Deng

Liu

et al. 2013

J Clin Pharm Ther

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“…Both liver safety parameters, SGOT and SGPT, were analysed by UV spectrophotometry (Huang et al, 2006) based on the oxidation of NADH to NAD. Serum creatinine was determined by an enzymatic method (Liu et al, 2012).…”

Section: Secondary Outcomesmentioning

confidence: 99%

A double‐blind, randomized, placebo‐controlled study to assess the efficacy of Andrographis paniculata standardized extract (ParActin®) on pain reduction in subjects with knee osteoarthritis

Hancke¹,

Srivastav

Cáceres

et al. 2019

Phytotherapy Research

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Andrographis paniculata Wall (Acanthaceae) is becoming more recognized for its anti‐inflammatory and antioxidant properties. A randomized, double‐blind, placebo‐controlled study was conducted to assess the efficacy of an andrographolide‐containing supplement, ParActin® (300 and 600 mg daily), on Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain reduction in patients with knee osteoarthritis. Joint stiffness, physical function, changes in the SF‐36 quality of life questionnaire, a fatigue scale, and safety were also evaluated. A total of 103 male and female patients with I‐II osteoarthritis of the knee joint were assessed. Patients treated with 300 or 600 mg/day of ParActin® showed a significant reduction in pain at days 28, 56, and 84 compared with a placebo group. WOMAC stiffness scores, physical function score, and the fatigue score showed a significant improvement in both ParActin®‐treated groups compared with the placebo group. At the end of the study, the quality of life (SF‐36 questionnaire) and Functional Assessment of Chronic Illness Therapy (FACIT) scores showed significant improvements in both ParActin®‐treated groups compared with the placebo group. Overall, it can be concluded that ParActin® in 300 and 600 mg/day dosages were found to be effective and safe in reducing pain in individuals suffering from mild to moderate knee osteoarthritis.

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“…SAC was measured by a modified BCP method (9). Urine creatinine was determined by an enzymatic method (10). Urine protein was measured by a dye -binding colorimetric method utilizing pyrogallol red-molybdate complex (11).…”

Section: Study Design and Subjectsmentioning

confidence: 99%

Influential factors on serum albumin concentration in hospitalized chronic kidney disease patients

et al. 2017

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: Background : Serum albumin concentration (SAC) is a prognostic factor that is affected by many factors such as postural change, liver function and food intake. Chronic kidney disease (CKD) patients excrete proteinuria, have low-protein diet, and receive glucocorticoid therapy. No one has evaluated the most influential factors on SAC in CKD patients. Methods : A retrospective study. Hospitalized CKD patients with less than 1 g/ gCreatinine proteinuria receiving glucocorticoid therapy (n=28), with 1 or more g/gCreatinine proteinuria not receiving glucocorticoid therapy (n=36), and with 1 or more g/gCreatinine proteinuria receiving glucocorticoid therapy (n =39) were enrolled. SAC, hemoglobin, proteinuria and blood pressure at the last outpatient check-up before hospitalization, on the second day of hospitalization, at the last laboratory examination before discharge, as well as at the first outpatient follow-up after discharge were analyzed. Results : SAC decreased on the second day of hospitalization and increased at the first outpatient follow-up significantly in all groups. Unexpectedly, the change of SAC was irrelevant to the amount of proteinuria. Conclusions : SAC was affected by not only proteinuria, but also postural change, physical activity, and food in CKD patients. SAC should be analyzed by standardizing a patient's condition during phlebotomy.

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Serum Creatinine Determined by Jaffe, Enzymatic Method, and Isotope Dilution‐Liquid Chromatography‐Mass Spectrometry in Patients Under Hemodialysis

Abstract: For uremic patients, in whom creatinine level is high and many of them suffered from diabetes mellitus, serum creatinine can be either under- or overestimated by Jaffe method. Enzymatic method is less affected and may be a better method.

Cited by 50 publications

References 19 publications

Predictive performance of reported population pharmacokinetic models of vancomycin in Chinese adult patients

Predictive performance of reported population pharmacokinetic models of vancomycin in Chinese adult patients

A double‐blind, randomized, placebo‐controlled study to assess the efficacy of Andrographis paniculata standardized extract (ParActin®) on pain reduction in subjects with knee osteoarthritis

Influential factors on serum albumin concentration in hospitalized chronic kidney disease patients

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