Serum Fructosamine and Retinopathy of Prematurity

Bozdağ, Şenol; Oğuz, Şerife Suna; Gökmen, Tülin; Tunay, Zühal Özen; Tök, Levent; Uraş, Nurdan; Erdeve, Ömer; Dilmen, Uğur

doi:10.1007/s12098-011-0515-9

Cited by 11 publications

(9 citation statements)

References 31 publications

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“…Some studies have documented alterations in ocular growth and changes in refractive errors in infants with ROP (9) . It is widely recognized that ROP is a multi-factorial condition, with gestational age, low birth weight, blood transfusion, oxygen exposure, intraventricular haemorrhage, and necrotizing enterocolitis all implicated in the disorder (10,11) . The aim of the present study was to determine the horizontal corneal diameter, central corneal thickness, and axial length in premature infants.…”

Section: Introductionmentioning

confidence: 99%

Analysis of the horizontal corneal diameter, central corneal thickness, and axial length in premature infants

Özdemir¹,

Tunay²,

Petriçli³

et al. 2014

Arquivos Brasileiros De Oftalmologia

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Purpose: To determine the horizontal corneal diameter, central corneal thickness, and axial length in premature infants. Methods: Infants with a birth weight of less than 2,500 g or with a gestation period of less than 36 weeks were included in the study. Infants with retinopathy of prematurity (ROP) were allocated to Group 1 (n=138), while those without ROP were allocated to Group 2 (n=236). All infants underwent a complete ophthalmologic examination, including corneal diameter measurements, pachymetry, biometry, and fundoscopy. Between-group comparisons of horizontal corneal diameter, central corneal thickness, and axial lengths were performed. Independent sample t-tests were used for statistical analysis. Results: Data was obtained from 374 eyes of 187 infants (102 female, 85 male). The mean gestational age at birth was 30.7 ± 2.7 weeks (range 25-36 weeks), the mean birth weight was 1,514 ± 533.3 g (range 750-1,970 g), and the mean postmenstrual age at examination was 40.0 ± 4.8 weeks. The mean gestational age and the mean birth weight of Group 1 were statistically lower than Group 2 (p<0.05). There were no significant differences in horizontal corneal diameter, central corneal thickness, and axial length between the two groups (p>0.05). Conclusions:The presence of ROP in premature infants does not alter the horizontal corneal diameter, central corneal thickness, or axial length.

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Section: Introductionmentioning

confidence: 99%

Analysis of the horizontal corneal diameter, central corneal thickness, and axial length in premature infants

Özdemir¹,

Tunay²,

Petriçli³

et al. 2014

Arquivos Brasileiros De Oftalmologia

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“…Seven out of the 9 studies provided primary data on the number of subjects with hyperglycemia and without hyperglycemia in both the ROP and non-ROP groups21222324252627. Pooling up data from these 7 studies showed that hyperglycemia is associated with ROP with an unadjusted OR of 4.16 (95% CI: 2.09–8.29, I 2 = 65%, P <0.0001) (Figure 2).…”

Section: Resultsmentioning

confidence: 99%

Association between hyperglycemia and retinopathy of prematurity: a systemic review and meta-analysis

Tang

Rong

et al. 2015

Sci Rep

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As the role of hyperglycemia in the development of retinopathy of prematurity (ROP) has not been well established, a meta-analysis of the association between hyperglycemia and ROP was conducted. Studies were identified through literature search in MEDLINE and EMBASE up to June 20, 2014 with keywords related to “hyperglycaemia” and “ROP”. Nine eligible studies involving 1939 neonates with 509 cases of ROP were included. Unadjusted analyses showed that hyperglycemia was significantly associated with ROP (Odds ratio [OR] = 4.16, P<0.0001). Comparing with the control, subjects in the ROP group had a significantly longer duration of hyperglycemia (Standardized mean difference [SMD] = 1.21, P< 0.0001), and higher mean glucose level. (SMD = 0.88, P = 0.0004) However, when combining the adjusted OR (after adjustment for birth weight, gestational age and other factors) provided from individual studies, only borderline significant association were observed on duration of hyperglycemia with ROP (adjusted OR 1.08, P = 0.03); and no significant association on mean glucose level with ROP (adjusted OR = 1.08, P = 0.15). Hence, hyperglycemia cannot be definitely considered as a risk factor for ROP, and further studies should adjust for potential confounding factors to clarify this association.

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“…It is concluded that "serum corrected fructosamine does not have a good predictive value in developing retinopathy of prematurity in verylow-birth-weight (VLBW) infants [1]." A concern is on the measurement of serum fructosamine in this work.…”

mentioning

confidence: 97%

“…Sir, The recent publication on serum fructosamine and retinopathy is very interesting [1]. It is concluded that "serum corrected fructosamine does not have a good predictive value in developing retinopathy of prematurity in verylow-birth-weight (VLBW) infants [1]."…”

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confidence: 99%

“…The first values of fructosamine in the cord blood of newborns were investigated to evaluate the trend of fructosamine levels (rate of expected increase in hyperglycemic infants) in comparison to subsequent levels rather than any pathologic correlation between the fetus and feto-maternal circulation as the author suggested [1,2]. Initially, it was hypothesized that if the neonates were exposed to hyperglycemia in the first two wk of life, this situation would be supported by an increased levels of serum fructosamine in subsequent 2-3 wk.…”

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confidence: 99%

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Serum Fructosamine in Neonate

Wiwanitkit¹,

Wiwanitkit²

2011

Indian J Pediatr

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Serum Fructosamine and Retinopathy of Prematurity

Abstract: Although the duration of hyperglycemia may contribute to the development of retinopathy of prematurity, serum corrected fructosamine does not have a good predictive value in developing retinopathy of prematurity in very-low-birth-weight (VLBW) infants.

Cited by 11 publications

References 31 publications

Analysis of the horizontal corneal diameter, central corneal thickness, and axial length in premature infants

Analysis of the horizontal corneal diameter, central corneal thickness, and axial length in premature infants

Association between hyperglycemia and retinopathy of prematurity: a systemic review and meta-analysis

Serum Fructosamine in Neonate

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