Serum gamma glutamyl transferase levels in association with lipids and lipoproteins in type2 diabetes mellitus

Relationship between liver enzymes and lipid profile in Pre-diabetes and type 2 diabetes mellitus patients

“…In T2DM, ALT showed significant positive correlation with TC and LDL-C similar to the studies of Al-Jameil et al [18] and saligram et al [19]. ALT causes diabetes by inducing insulin resistance [20] with hepatic steatosis which in turn aggravates insulin resistance and creates vicious cycle [21].GGT showed significant positive correlation with TC, TGL, LDL and VLDL in accordance with previous study of Rajarajeshwari D et al [22]. Increase in GGT may be due to excess deposition of fat in liver [23].…”

In utero exposure to parabens and early childhood BMI z-scores – Associations between placental ethyl paraben, longitudinal BMI trajectories and cord blood metabolic biomarkers

“…Our finding that placental EtP is significantly and positively associated with cord blood GGT may partly explain the previously described obesogenic effects of parabens. In adults, serum GGT activity was found associated with fasting insulin ( Matsha et al, 2014 , Rantala et al, 2000 ), HDL and LDL ( Lippi et al, 2007 , Rajarajeswari et al, 2014 ) levels, and hypertension ( Bonnet et al, 2017 , Rantala et al, 2000 ). It may be considered a possible sensitive and early biomarker for developing type 2 diabetes and metabolic syndrome ( Kim et al, 2005 , Lee et al, 2003 , Lee et al, 2007a , Sabanayagam et al, 2009 , Zhao et al, 2020 ).…”