Serum Gamma Glutamyl Transferase – A Predictor of Nephropathy in Newly Diagnosed Type 2 Diabetes Mellitus Patients

Abstract

Background: Diabetes mellitus is one of the most common metabolic conditions characterized by hyperglycemia, there is a higher frequency of chronic complications at the time of clinical diagnosis, hence need a better screening tool for its prevention. To nd the Aims and Objective: association of Serum GGT level with microalbuminuria in newly diagnosed Type 2 diabetes mellitus patients. sample Materials and Methods: was collected from 80 newly detected type 2 diabetes patients and they were screened for microalbuminuria, HBA1C and serum GGT levels, and realation of microalbuminuria with serum GGT and HBA1C was analysed. Among t Results: hese 80 patients 42 patients(52.5%) had microalbunimuria, on testing serum gamma glutamyl transferase levels in these patients 41 patients(52.5%) had high serum GGT levels, on studying microalbuminuria with serum GGT levels presence of micro albuminuria was high in patients with high levels of serum GGT as compared to patients with normal serum GGT, which showed a statistical signicance with r= 0.56, p<0.001 we found that serum GGT level Conclusion: increases with increase in microalbuminuria levels in newly detected type2 diabetes patients and hence conclude that serum GGT could be used as an easy predictor of microvascular complication of diabetes.