Background: Malaria is one of the common causes of acute febrile illness in tropical countries. Malaria presents with varied manifestations. This retrospective study carried to know the clinical profile and laboratory abnormalities seen in malaria patients.Methods: The data was collected retrospectively from 1st January to 31st December 2017. Inclusion criteria: all fever cases above 15 years of age of both the sexes diagnosed as malaria by peripheral smear examination and malaria card test. Exclusion criteria: combined malaria with other fevers such as dengue, chikangunya. Fever cases negative for malaria tests. Malaria cases with history of chronic kidney disease, chronic liver disease such as cirrhosis of liver, chronic viral hepatitis, liver abscess, and chronic illness such as rheumatoid arthritis, diabetes, and hypertension. The data regarding the clinical presentation of patients and laboratory values such as hemoglobin, total leukocytecount, platelet count, total bilirubin, SGOT, SGPT, albumin values collected and analyzed with tables and percentage.Results: A total of 57 malaria cases were analyzed, 71.9 % males, 28.1% were females. The commonest age group was between 15- 30 years (61.4%). 29 patients (50.9%) had P. vivax, 20 patients (35.1%) P. falciparum and 8 patients (14%) mixed infection. The most common clinical presentation was fever with chills (100%) followed by vomiting (68.4%), splenomegaly (56.1%), headache (45.6%), pain abdomen (43.9%).19 cases (33.3%)  had hemoglobin less than 10gm/dl; 42 cases (73.6%) had thrombocytopenia; 46 cases (80.7%) had urea ≥30mg/dl; 14 cases (24.6%) had creatinine ≥1.4; 26 cases (45.6%) had total bilirubin >1.2mg/dl ; 17 cases (29.8%) had SGOT >45 IU; 33 cases (57.9%) had SGPT > 45 IU and 32 cases (56.1%) had albumin level ≤3.5gm/dl.Conclusions: In the study malaria due to P. vivax was more common than P. falciparum, malaria affected young adults, males more than females. Reduced hemoglobin and platelet count, deranged liver and renal function and reduced serum albumin seen commonly in malaria.

Background: Diabetes mellitus is one of the most common metabolic conditions characterized by hyperglycemia, there is a higher frequency of chronic complications at the time of clinical diagnosis, hence need a better screening tool for its prevention. To nd the Aims and Objective: association of Serum GGT level with microalbuminuria in newly diagnosed Type 2 diabetes mellitus patients. sample Materials and Methods: was collected from 80 newly detected type 2 diabetes patients and they were screened for microalbuminuria, HBA1C and serum GGT levels, and realation of microalbuminuria with serum GGT and HBA1C was analysed. Among t Results: hese 80 patients 42 patients(52.5%) had microalbunimuria, on testing serum gamma glutamyl transferase levels in these patients 41 patients(52.5%) had high serum GGT levels, on studying microalbuminuria with serum GGT levels presence of micro albuminuria was high in patients with high levels of serum GGT as compared to patients with normal serum GGT, which showed a statistical signicance with r= 0.56, p<0.001 we found that serum GGT level Conclusion: increases with increase in microalbuminuria levels in newly detected type2 diabetes patients and hence conclude that serum GGT could be used as an easy predictor of microvascular complication of diabetes.

of diagnosed pulmonary embolism is 71 to 117 per 100,000 person-years. [5][6][7] Pulmonary embolism silently kills around half of patients who die of pulmonary embolism and were diagnosed with this problem prior to death. 8 Risk factors includes advanced age, prolonged immobility, surgery, trauma, malignancy, pregnancy, estrogen therapy, congestive heart failure, and inherited or acquired defects in blood coagulation factors.The quantitative plasma d-dimer rises in the presence of PE or deep venous thrombosis because of the breakdown ABSTRACT Background: Pulmonary embolism (PE), is one of the major cardiovascular causes of death. Pulmonary embolus (PE) can be fatal but is often treatable if recognized early. Unfortunately, the clinical presentation of PE is often variable and misleading mimicking other illnesses and hence known as "the Great Masquerader," making diagnosis difficult. The D-dimer assay has recently come into favour as a method to exclude PE; however, this test has an acceptable safety margin only in low-risk populations. Methods: Present study included 35 patients with clinical suspicion of pulmonary embolism admitted at the tertiary care hospital of North Karnataka during the period from October 2016 to September 2017. Patients were classified according to final diagnosis by CT Pulmonary Angiography into 28 cases positive for PE (80%) and 7 cases negative for PE (20%). Results: Present study included 35 cases suspected to have PE (26 males and 9 females). Their age ranged from 33 to 72 years, with a mean age 48.9 ±14.2 years. 28 cases positive for PE (80%) and 7 cases negative for PE (20%). The mean age of positive and negative PE cases was 48.1±11.2 and 46.4±8.8 respectively. Results of D-dimer test were positive in 10 cases (35.7%) and were negative in 18 cases (61.3 %) of PE. Conclusions: This report highlights the risk of misdiagnosing PE if relying solely on ELISA D-dimer for exclusion. This report documents the presentation of PE despite having unremarkable ELISA D-dimer measurements and highlights the importance of clinical suspicion.